STRINGSTRING
cdc26 cdc26 ENSXCOP00000011395 ENSXCOP00000011395 ENSXCOP00000011385 ENSXCOP00000011385 ENSXCOP00000011179 ENSXCOP00000011179 ENSXCOP00000000156 ENSXCOP00000000156 Psmc5 Psmc5 Psma1 Psma1 ENSXCOP00000000492 ENSXCOP00000000492 ENSXCOP00000000525 ENSXCOP00000000525 PSMA4 PSMA4 rpa2 rpa2 mcm7 mcm7 psmd9 psmd9 Psmd5 Psmd5 Kpnb1 Kpnb1 ENSXCOP00000001970 ENSXCOP00000001970 Psmd14 Psmd14 pola2 pola2 ENSXCOP00000003123 ENSXCOP00000003123 LOC114151785 LOC114151785 ENSXCOP00000003408 ENSXCOP00000003408 ENSXCOP00000003604 ENSXCOP00000003604 ENSXCOP00000003814 ENSXCOP00000003814 Rpa3 Rpa3 LOC114156671 LOC114156671 LOC114156669 LOC114156669 Kpna6 Kpna6 ENSXCOP00000004149 ENSXCOP00000004149 Psmd1 Psmd1 Mcm10 Mcm10 H2AZ1 H2AZ1 LOC114138068 LOC114138068 ENSXCOP00000004968 ENSXCOP00000004968 Psme3 Psme3 ENSXCOP00000005272 ENSXCOP00000005272 ENSXCOP00000005673 ENSXCOP00000005673 Orc3 Orc3 PSMD2 PSMD2 HIST1H2BA HIST1H2BA ENSXCOP00000006663 ENSXCOP00000006663 Psme1 Psme1 ENSXCOP00000007098 ENSXCOP00000007098 ENSXCOP00000007241 ENSXCOP00000007241 uba52 uba52 anapc16 anapc16 ENSXCOP00000008263 ENSXCOP00000008263 psmc6 psmc6 ENSXCOP00000008629 ENSXCOP00000008629 ENSXCOP00000008859 ENSXCOP00000008859 ENSXCOP00000008872 ENSXCOP00000008872 ENSXCOP00000008982 ENSXCOP00000008982 ENSXCOP00000009078 ENSXCOP00000009078 ENSXCOP00000009535 ENSXCOP00000009535 ENSXCOP00000009556 ENSXCOP00000009556 ENSXCOP00000009597 ENSXCOP00000009597 ENSXCOP00000009598 ENSXCOP00000009598 ENSXCOP00000009602 ENSXCOP00000009602 Anapc10 Anapc10 ENSXCOP00000009823 ENSXCOP00000009823 ENSXCOP00000009982 ENSXCOP00000009982 LOC114147096 LOC114147096 ENSXCOP00000010411 ENSXCOP00000010411 ENSXCOP00000010446 ENSXCOP00000010446 ENSXCOP00000010728 ENSXCOP00000010728 Mcm2 Mcm2 FZR1 FZR1 Psmc1 Psmc1 Psmc4 Psmc4 ENSXCOP00000027383 ENSXCOP00000027383 psmd7 psmd7 gmnn gmnn ENSXCOP00000026249 ENSXCOP00000026249 ENSXCOP00000026215 ENSXCOP00000026215 psmb4 psmb4 Fam89a Fam89a psmb2 psmb2 Cdc16 Cdc16 CDK2 CDK2 psma5 psma5 Cdc27 Cdc27 ENSXCOP00000024366 ENSXCOP00000024366 ENSXCOP00000024324 ENSXCOP00000024324 ENSXCOP00000024046 ENSXCOP00000024046 LOC114149001 LOC114149001 LOC114149126 LOC114149126 Pole Pole Psma2 Psma2 Orc4 Orc4 psmb7 psmb7 ENSXCOP00000020986 ENSXCOP00000020986 Psme2 Psme2 Tm7sf3 Tm7sf3 Anapc5 Anapc5 ENSXCOP00000020233 ENSXCOP00000020233 ENSXCOP00000020133 ENSXCOP00000020133 LOC114146450 LOC114146450 Psmd12 Psmd12 ENSXCOP00000019701 ENSXCOP00000019701 ENSXCOP00000018820 ENSXCOP00000018820 ENSXCOP00000018801 ENSXCOP00000018801 ENSXCOP00000018797 ENSXCOP00000018797 ENSXCOP00000018793 ENSXCOP00000018793 Psma6 Psma6 ENSXCOP00000017691 ENSXCOP00000017691 ENSXCOP00000017667 ENSXCOP00000017667 ENSXCOP00000017612 ENSXCOP00000017612 Psmb6 Psmb6 ENSXCOP00000017338 ENSXCOP00000017338 ENSXCOP00000017337 ENSXCOP00000017337 ENSXCOP00000017291 ENSXCOP00000017291 Anapc15 Anapc15 Psmb1 Psmb1 Psmc3 Psmc3 ENSXCOP00000015777 ENSXCOP00000015777 Prim2 Prim2 ENSXCOP00000015627 ENSXCOP00000015627 ENSXCOP00000015576 ENSXCOP00000015576 ENSXCOP00000015546 ENSXCOP00000015546 HIST1H4J HIST1H4J ENSXCOP00000015465 ENSXCOP00000015465 Prim1 Prim1 anapc11 anapc11 Psmb3 Psmb3 ENSXCOP00000015019 ENSXCOP00000015019 Psmd10 Psmd10 ENSXCOP00000014609 ENSXCOP00000014609 Pole4 Pole4 ENSXCOP00000014165 ENSXCOP00000014165 ENSXCOP00000013978 ENSXCOP00000013978 psmd6 psmd6 ENSXCOP00000013308 ENSXCOP00000013308 Kpna1 Kpna1 ENSXCOP00000013093 ENSXCOP00000013093 ENSXCOP00000012693 ENSXCOP00000012693 ENSXCOP00000012493 ENSXCOP00000012493 anapc7 anapc7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdc26Cell division cycle 26 homolog. (94 aa)
ENSXCOP00000011395Anaphase promoting complex subunit 4. (761 aa)
ENSXCOP00000011385BRD4 interacting chromatin remodeling complex associated protein. (1279 aa)
ENSXCOP00000011179Proteasome subunit alpha type. (233 aa)
ENSXCOP00000000156Anaphase promoting complex subunit 2; Belongs to the cullin family. (704 aa)
Psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (398 aa)
Psma1Proteasome subunit alpha type. (262 aa)
ENSXCOP00000000492Histone H2B; Belongs to the histone H2B family. (147 aa)
ENSXCOP00000000525Histone H2A; Belongs to the histone H2A family. (131 aa)
PSMA4Proteasome subunit beta; Belongs to the peptidase T1B family. (237 aa)
rpa2Replication protein A2. (278 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (724 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
Psmd5Proteasome 26S subunit, non-ATPase 5. (505 aa)
Kpnb1Karyopherin (importin) beta 1. (291 aa)
ENSXCOP00000001970Importin N-terminal domain-containing protein. (182 aa)
Psmd14Proteasome 26S subunit, non-ATPase 14. (302 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (604 aa)
ENSXCOP00000003123Proteasome inhibitor subunit 1. (267 aa)
LOC114151785Histone H3; Belongs to the histone H3 family. (136 aa)
ENSXCOP00000003408CDC45 cell division cycle 45 homolog (S. cerevisiae). (527 aa)
ENSXCOP00000003604Histone H3; Belongs to the histone H3 family. (137 aa)
ENSXCOP00000003814Methionine sulfoxide reductase B1b. (403 aa)
Rpa3Replication protein A3. (120 aa)
LOC114156671Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (195 aa)
LOC114156669UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
Kpna6Importin subunit alpha; Belongs to the importin alpha family. (524 aa)
ENSXCOP00000004149PI31_Prot_N domain-containing protein. (154 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (951 aa)
Mcm10Zf-primase domain-containing protein. (210 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (107 aa)
LOC114138068Ribosomal protein S27a. (156 aa)
ENSXCOP00000004968DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (523 aa)
Psme3Proteasome activator subunit 3. (255 aa)
ENSXCOP00000005272BRD4 interacting chromatin remodeling complex associated protein like. (722 aa)
ENSXCOP00000005673Histone H3; Belongs to the histone H3 family. (138 aa)
Orc3Origin recognition complex, subunit 3. (684 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (828 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (115 aa)
ENSXCOP00000006663Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
Psme1Proteasome activator subunit 1. (259 aa)
ENSXCOP00000007098Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (301 aa)
ENSXCOP00000007241Histone H2A; Belongs to the histone H2A family. (132 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
ENSXCOP00000008263Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (760 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
ENSXCOP00000008629Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (568 aa)
ENSXCOP00000008859Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa)
ENSXCOP00000008872DNA polymerase. (1344 aa)
ENSXCOP00000008982Family with sequence similarity 89 member B. (140 aa)
ENSXCOP00000009078Histone H2A; Belongs to the histone H2A family. (137 aa)
ENSXCOP00000009535Histone H2A; Belongs to the histone H2A family. (138 aa)
ENSXCOP00000009556Histone H2B; Belongs to the histone H2B family. (112 aa)
ENSXCOP00000009597UBIQUITIN_CONJUGAT_2 domain-containing protein. (123 aa)
ENSXCOP00000009598Uncharacterized protein. (113 aa)
ENSXCOP00000009602Cell division cycle 7 homolog (S. cerevisiae); Belongs to the protein kinase superfamily. (435 aa)
Anapc10Anaphase promoting complex subunit 10. (118 aa)
ENSXCOP00000009823Anaphase promoting complex subunit 10. (79 aa)
ENSXCOP00000009982Fizzy/cell division cycle 20 related 1b. (483 aa)
LOC114147096Proteasome subunit beta. (271 aa)
ENSXCOP00000010411Origin recognition complex, subunit 2. (391 aa)
ENSXCOP00000010446DNA helicase; Belongs to the MCM family. (662 aa)
ENSXCOP00000010728CDC23 (cell division cycle 23, yeast, homolog). (524 aa)
Mcm2DNA helicase; Belongs to the MCM family. (902 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (493 aa)
Psmc1Proteasome 26S subunit, ATPase 1b. (257 aa)
Psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (401 aa)
ENSXCOP00000027383KxDL motif containing 1. (193 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (330 aa)
gmnnGeminin DNA replication inhibitor. (216 aa)
ENSXCOP00000026249DBF4 zinc finger. (527 aa)
ENSXCOP00000026215Proteasome 26S subunit, non-ATPase 4b. (350 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
Fam89aFamily with sequence similarity 89 member A. (148 aa)
psmb2Proteasome subunit beta. (199 aa)
Cdc16Cell division cycle 16 homolog (S. cerevisiae). (498 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (264 aa)
psma5Proteasome subunit alpha type. (241 aa)
Cdc27Cell division cycle 27. (329 aa)
ENSXCOP00000024366Cell division cycle 27. (412 aa)
ENSXCOP00000024324Proteasome 26S subunit, non-ATPase 3. (462 aa)
ENSXCOP00000024046Histone domain-containing protein. (267 aa)
LOC114149001Ubiquitin-like domain-containing protein. (77 aa)
LOC114149126Proteasome subunit beta. (301 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2225 aa)
Psma2Proteasome endopeptidase complex. (164 aa)
Orc4AAA_16 domain-containing protein. (142 aa)
psmb7Proteasome subunit beta. (298 aa)
ENSXCOP00000020986Minichromosome maintenance complex component 5; Belongs to the MCM family. (688 aa)
Psme2Proteasome activator subunit 2. (273 aa)
Tm7sf3Transmembrane 7 superfamily member 3. (554 aa)
Anapc5Anaphase promoting complex subunit 5. (740 aa)
ENSXCOP00000020233Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (393 aa)
ENSXCOP00000020133DNA helicase; Belongs to the MCM family. (810 aa)
LOC114146450Histone H2B; Belongs to the histone H2B family. (116 aa)
Psmd12Proteasome 26S subunit, non-ATPase 12. (436 aa)
ENSXCOP00000019701Origin recognition complex, subunit 5. (400 aa)
ENSXCOP00000018820Chromatin licensing and DNA replication factor 1. (634 aa)
ENSXCOP00000018801Proteasome subunit beta 9a. (170 aa)
ENSXCOP00000018797Proteasome subunit beta 12. (192 aa)
ENSXCOP00000018793Proteasome subunit beta 13a. (218 aa)
Psma6Proteasome subunit alpha type. (252 aa)
ENSXCOP00000017691Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa)
ENSXCOP00000017667annotation not available (93 aa)
ENSXCOP00000017612Histone H2B; Belongs to the histone H2B family. (111 aa)
Psmb6Proteasome subunit beta 6. (251 aa)
ENSXCOP00000017338Histone H2B; Belongs to the histone H2B family. (134 aa)
ENSXCOP00000017337Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSXCOP00000017291Histone H2A; Belongs to the histone H2A family. (126 aa)
Anapc15Anaphase promoting complex subunit 15. (119 aa)
Psmb1Proteasome subunit beta. (240 aa)
Psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (421 aa)
ENSXCOP00000015777Histone H3; Belongs to the histone H3 family. (115 aa)
Prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (499 aa)
ENSXCOP00000015627Histone H2B; Belongs to the histone H2B family. (151 aa)
ENSXCOP00000015576Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSXCOP00000015546Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (683 aa)
HIST1H4JHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
ENSXCOP00000015465Histone H2B; Belongs to the histone H2B family. (124 aa)
Prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
Psmb3Proteasome subunit beta. (204 aa)
ENSXCOP00000015019Uncharacterized protein. (423 aa)
Psmd10ANK_REP_REGION domain-containing protein. (73 aa)
ENSXCOP00000014609Proteasome subunit beta 8A. (160 aa)
Pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (145 aa)
ENSXCOP00000014165SCY domain-containing protein. (122 aa)
ENSXCOP00000013978Proteasome 26S subunit, non-ATPase 11a. (420 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
ENSXCOP00000013308Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (589 aa)
Kpna1Importin subunit alpha; Belongs to the importin alpha family. (510 aa)
ENSXCOP00000013093Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (554 aa)
ENSXCOP00000012693Proteasome 26S subunit, non-ATPase 13. (357 aa)
ENSXCOP00000012493DNA helicase; Belongs to the MCM family. (757 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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