STRINGSTRING
LOC114136223 LOC114136223 Tp53 Tp53 Psmd14 Psmd14 Psmd5 Psmd5 ENSXCOP00000001765 ENSXCOP00000001765 psmd9 psmd9 PSMA4 PSMA4 ENSXCOP00000000335 ENSXCOP00000000335 Psma1 Psma1 Psmc5 Psmc5 ENSXCOP00000028006 ENSXCOP00000028006 Psmc4 Psmc4 ENSXCOP00000027383 ENSXCOP00000027383 psmd7 psmd7 ENSXCOP00000026321 ENSXCOP00000026321 ENSXCOP00000026215 ENSXCOP00000026215 psmb4 psmb4 psmb2 psmb2 CDK2 CDK2 ENSXCOP00000024845 ENSXCOP00000024845 ENSXCOP00000024680 ENSXCOP00000024680 psma5 psma5 ENSXCOP00000024324 ENSXCOP00000024324 Ccne1 Ccne1 ENSXCOP00000023454 ENSXCOP00000023454 ENSXCOP00000023176 ENSXCOP00000023176 LOC114149001 LOC114149001 Znf385c Znf385c LOC114149126 LOC114149126 Psma2 Psma2 ENSXCOP00000022211 ENSXCOP00000022211 ENSXCOP00000022210 ENSXCOP00000022210 psmb7 psmb7 Psme2 Psme2 ENSXCOP00000020233 ENSXCOP00000020233 ccna2 ccna2 Psmd12 Psmd12 psma8 psma8 LOC114160673 LOC114160673 ENSXCOP00000018801 ENSXCOP00000018801 ENSXCOP00000018797 ENSXCOP00000018797 ENSXCOP00000018793 ENSXCOP00000018793 ENSXCOP00000018558 ENSXCOP00000018558 Psma6 Psma6 Psmb6 Psmb6 ENSXCOP00000016575 ENSXCOP00000016575 Psmb1 Psmb1 Psmc3 Psmc3 ENSXCOP00000015358 ENSXCOP00000015358 Psmb3 Psmb3 Psmd10 Psmd10 ENSXCOP00000014609 ENSXCOP00000014609 ENSXCOP00000013978 ENSXCOP00000013978 psmd6 psmd6 Ccna1 Ccna1 Psme4 Psme4 ENSXCOP00000012693 ENSXCOP00000012693 ENSXCOP00000011233 ENSXCOP00000011233 ENSXCOP00000011179 ENSXCOP00000011179 Psmc1 Psmc1 ENSXCOP00000011040 ENSXCOP00000011040 ENSXCOP00000010457 ENSXCOP00000010457 ENSXCOP00000010336 ENSXCOP00000010336 LOC114147096 LOC114147096 psmc6 psmc6 ENSXCOP00000008206 ENSXCOP00000008206 uba52 uba52 ENSXCOP00000007366 ENSXCOP00000007366 ENSXCOP00000007098 ENSXCOP00000007098 Psme1 Psme1 Psme3 Psme3 LOC114138068 LOC114138068 Psmd1 Psmd1 ENSXCOP00000004149 ENSXCOP00000004149 ENSXCOP00000003123 ENSXCOP00000003123
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC114136223Cyclin-dependent kinase inhibitor 1A. (156 aa)
Tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (332 aa)
Psmd14Proteasome 26S subunit, non-ATPase 14. (302 aa)
Psmd5Proteasome 26S subunit, non-ATPase 5. (505 aa)
ENSXCOP00000001765Zinc finger protein 385A. (317 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
PSMA4Proteasome subunit beta; Belongs to the peptidase T1B family. (237 aa)
ENSXCOP00000000335ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2879 aa)
Psma1Proteasome subunit alpha type. (262 aa)
Psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (398 aa)
ENSXCOP00000028006Cyclin-dependent kinase inhibitor 1Bb. (176 aa)
Psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (401 aa)
ENSXCOP00000027383KxDL motif containing 1. (193 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (330 aa)
ENSXCOP00000026321Uncharacterized protein. (397 aa)
ENSXCOP00000026215Proteasome 26S subunit, non-ATPase 4b. (350 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
psmb2Proteasome subunit beta. (199 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (264 aa)
ENSXCOP00000024845Uncharacterized protein. (423 aa)
ENSXCOP00000024680MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (456 aa)
psma5Proteasome subunit alpha type. (241 aa)
ENSXCOP00000024324Proteasome 26S subunit, non-ATPase 3. (462 aa)
Ccne1Cyclin E1; Belongs to the cyclin family. (284 aa)
ENSXCOP00000023454Uncharacterized protein. (101 aa)
ENSXCOP00000023176Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa)
LOC114149001Ubiquitin-like domain-containing protein. (77 aa)
Znf385cZinc finger protein 385C. (210 aa)
LOC114149126Proteasome subunit beta. (301 aa)
Psma2Proteasome endopeptidase complex. (164 aa)
ENSXCOP00000022211Uncharacterized protein. (100 aa)
ENSXCOP00000022210Uncharacterized protein. (75 aa)
psmb7Proteasome subunit beta. (298 aa)
Psme2Proteasome activator subunit 2. (273 aa)
ENSXCOP00000020233Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (393 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (432 aa)
Psmd12Proteasome 26S subunit, non-ATPase 12. (436 aa)
psma8Proteasome subunit alpha type. (251 aa)
LOC114160673Cyclin-dependent kinase inhibitor 1D. (178 aa)
ENSXCOP00000018801Proteasome subunit beta 9a. (170 aa)
ENSXCOP00000018797Proteasome subunit beta 12. (192 aa)
ENSXCOP00000018793Proteasome subunit beta 13a. (218 aa)
ENSXCOP00000018558Peptidase_S39 domain-containing protein. (152 aa)
Psma6Proteasome subunit alpha type. (252 aa)
Psmb6Proteasome subunit beta 6. (251 aa)
ENSXCOP00000016575Checkpoint kinase 2. (499 aa)
Psmb1Proteasome subunit beta. (240 aa)
Psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (421 aa)
ENSXCOP00000015358MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (454 aa)
Psmb3Proteasome subunit beta. (204 aa)
Psmd10ANK_REP_REGION domain-containing protein. (73 aa)
ENSXCOP00000014609Proteasome subunit beta 8A. (160 aa)
ENSXCOP00000013978Proteasome 26S subunit, non-ATPase 11a. (420 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
Ccna1Cyclin A1; Belongs to the cyclin family. (397 aa)
Psme4Proteasome activator subunit 4a. (1804 aa)
ENSXCOP00000012693Proteasome 26S subunit, non-ATPase 13. (357 aa)
ENSXCOP00000011233Proteasome subunit beta. (287 aa)
ENSXCOP00000011179Proteasome subunit alpha type. (233 aa)
Psmc1Proteasome 26S subunit, ATPase 1b. (257 aa)
ENSXCOP00000011040Cyclin-dependent kinase inhibitor 1Cb. (219 aa)
ENSXCOP00000010457COP1 E3 ubiquitin ligase. (645 aa)
ENSXCOP00000010336Proteasome subunit beta. (287 aa)
LOC114147096Proteasome subunit beta. (271 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
ENSXCOP00000008206Uncharacterized protein. (454 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ENSXCOP00000007366Proteasome activator subunit 4b. (1682 aa)
ENSXCOP00000007098Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (301 aa)
Psme1Proteasome activator subunit 1. (259 aa)
Psme3Proteasome activator subunit 3. (255 aa)
LOC114138068Ribosomal protein S27a. (156 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (951 aa)
ENSXCOP00000004149PI31_Prot_N domain-containing protein. (154 aa)
ENSXCOP00000003123Proteasome inhibitor subunit 1. (267 aa)
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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