(34 nodes) MET promotes cell motility network (Xiphophorus couchianus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

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Your Input:
	Hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (708 aa)
	TNS1	Tensin 1. (974 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (299 aa)
	Fndc3a	Fibronectin type III domain containing 3A. (1215 aa)
	ENSXCOP00000008251	Laminin, alpha 4. (1725 aa)
	DOCK7	Dedicator of cytokinesis 7; Belongs to the DOCK family. (1959 aa)
	ENSXCOP00000008373	Uncharacterized protein. (133 aa)
	Col24a1	Fibrillar collagen NC1 domain-containing protein. (116 aa)
	ENSXCOP00000009526	PH domain-containing protein. (389 aa)
	ENSXCOP00000000064	Laminin, beta 2 (laminin S). (1373 aa)
	LOC114140865	Tyrosine-protein kinase. (527 aa)
	Grb2	Growth factor receptor-bound protein 2b. (210 aa)
	ENSXCOP00000000690	Uncharacterized protein. (126 aa)
	ENSXCOP00000001047	Laminin N-terminal domain-containing protein. (243 aa)
	ENSXCOP00000001062	Uncharacterized protein. (121 aa)
	ENSXCOP00000001764	Rap guanine nucleotide exchange factor (GEF) 1b. (1048 aa)
	Col27a1	Fibrillar collagen NC1 domain-containing protein. (112 aa)
	CRK	CRK proto-oncogene, adaptor protein. (315 aa)
	ENSXCOP00000006293	Sema domain-containing protein. (702 aa)
	Met	Protein kinase domain-containing protein. (237 aa)
	ENSXCOP00000012044	Uncharacterized protein. (130 aa)
	ENSXCOP00000013098	Collagen, type XXVII, alpha 1b. (1035 aa)
	ENSXCOP00000013325	Uncharacterized protein. (980 aa)
	ENSXCOP00000014719	GRB2-associated binding protein 1. (697 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (136 aa)
	ENSXCOP00000018445	Uncharacterized protein. (72 aa)
	Fndc3b	Fibronectin type III domain containing 3Ba. (1174 aa)
	ENSXCOP00000019655	Uncharacterized protein. (549 aa)
	ENSXCOP00000019677	Uncharacterized protein. (1734 aa)
	TNS3	Tensin 3. (1200 aa)
	ENSXCOP00000021625	Uncharacterized protein. (396 aa)
	SRC	Tyrosine-protein kinase. (559 aa)
	ENSXCOP00000022542	Uncharacterized protein. (511 aa)
	ENSXCOP00000026756	Laminin, gamma 1. (1148 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRK	ENSXCOP00000001764	ENSXCOP00000005850	ENSXCOP00000001764	CRK proto-oncogene, adaptor protein.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.954
CRK	ENSXCOP00000006293	ENSXCOP00000005850	ENSXCOP00000006293	CRK proto-oncogene, adaptor protein.	Sema domain-containing protein.	0.710
CRK	ENSXCOP00000009526	ENSXCOP00000005850	ENSXCOP00000009526	CRK proto-oncogene, adaptor protein.	PH domain-containing protein.	0.695
CRK	ENSXCOP00000014719	ENSXCOP00000005850	ENSXCOP00000014719	CRK proto-oncogene, adaptor protein.	GRB2-associated binding protein 1.	0.695
CRK	ENSXCOP00000018445	ENSXCOP00000005850	ENSXCOP00000018445	CRK proto-oncogene, adaptor protein.	Uncharacterized protein.	0.520
CRK	Grb2	ENSXCOP00000005850	ENSXCOP00000000623	CRK proto-oncogene, adaptor protein.	Growth factor receptor-bound protein 2b.	0.835
CRK	Hgf	ENSXCOP00000005850	ENSXCOP00000027251	CRK proto-oncogene, adaptor protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.417
CRK	LOC114140865	ENSXCOP00000005850	ENSXCOP00000000604	CRK proto-oncogene, adaptor protein.	Tyrosine-protein kinase.	0.525
CRK	Met	ENSXCOP00000005850	ENSXCOP00000006308	CRK proto-oncogene, adaptor protein.	Protein kinase domain-containing protein.	0.710
CRK	RAP1B	ENSXCOP00000005850	ENSXCOP00000017152	CRK proto-oncogene, adaptor protein.	RAP1B, member of RAS oncogene family.	0.520
CRK	SRC	ENSXCOP00000005850	ENSXCOP00000021988	CRK proto-oncogene, adaptor protein.	Tyrosine-protein kinase.	0.525
CRK	crkl	ENSXCOP00000005850	ENSXCOP00000006931	CRK proto-oncogene, adaptor protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.912
DOCK7	ENSXCOP00000006293	ENSXCOP00000008370	ENSXCOP00000006293	Dedicator of cytokinesis 7; Belongs to the DOCK family.	Sema domain-containing protein.	0.418
DOCK7	ENSXCOP00000008373	ENSXCOP00000008370	ENSXCOP00000008373	Dedicator of cytokinesis 7; Belongs to the DOCK family.	Uncharacterized protein.	0.897
DOCK7	Met	ENSXCOP00000008370	ENSXCOP00000006308	Dedicator of cytokinesis 7; Belongs to the DOCK family.	Protein kinase domain-containing protein.	0.418
ENSXCOP00000000064	ENSXCOP00000000690	ENSXCOP00000000064	ENSXCOP00000000690	Laminin, beta 2 (laminin S).	Uncharacterized protein.	0.641
ENSXCOP00000000064	ENSXCOP00000001047	ENSXCOP00000000064	ENSXCOP00000001047	Laminin, beta 2 (laminin S).	Laminin N-terminal domain-containing protein.	0.641
ENSXCOP00000000064	ENSXCOP00000001062	ENSXCOP00000000064	ENSXCOP00000001062	Laminin, beta 2 (laminin S).	Uncharacterized protein.	0.641
ENSXCOP00000000064	ENSXCOP00000008251	ENSXCOP00000000064	ENSXCOP00000008251	Laminin, beta 2 (laminin S).	Laminin, alpha 4.	0.544
ENSXCOP00000000064	ENSXCOP00000012044	ENSXCOP00000000064	ENSXCOP00000012044	Laminin, beta 2 (laminin S).	Uncharacterized protein.	0.641