46 items (Xiphophorus couchianus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (147 aa)
	ENSXCOP00000027485	COesterase domain-containing protein. (87 aa)
	ENSXCOP00000027484	COesterase domain-containing protein. (266 aa)
	ENSXCOP00000027479	COesterase domain-containing protein. (250 aa)
	ENSXCOP00000027383	KxDL motif containing 1. (193 aa)
	mylip	Myosin regulatory light chain interacting protein a. (481 aa)
	Cdcp2	CUB domain containing protein 2. (390 aa)
	ENSXCOP00000025344	CUB domain-containing protein. (151 aa)
	ENSXCOP00000025274	Immunoglobulin-like domain containing receptor 2. (557 aa)
	Lipa	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (369 aa)
	ENSXCOP00000023803	Alpha_adaptinC2 domain-containing protein. (850 aa)
	ENSXCOP00000023203	Scavenger receptor class B, member 1; Belongs to the CD36 family. (484 aa)
	LOC114149001	Ubiquitin-like domain-containing protein. (77 aa)
	Npc1	Niemann-Pick disease, type C1. (1223 aa)
	ENSXCOP00000020729	Uncharacterized protein. (423 aa)
	ENSXCOP00000019917	COesterase domain-containing protein. (88 aa)
	ENSXCOP00000019705	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (235 aa)
	ENSXCOP00000018688	Uncharacterized protein. (283 aa)
	Nr1h3	Nuclear receptor subfamily 1, group H, member 3. (421 aa)
	ENSXCOP00000017948	Low density lipoprotein receptor b. (840 aa)
	ENSXCOP00000017748	Apolipoprotein Ba. (4198 aa)
	Ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (150 aa)
	LOC114151353	Vitellogenin 3, phosvitinless. (1243 aa)
	ENSXCOP00000004323	Low density lipoprotein receptor adaptor protein 1a. (143 aa)
	ENSXCOP00000004811	Apolipoprotein Bb, tandem duplicate 2. (2207 aa)
	LOC114138068	Ribosomal protein S27a. (156 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ENSXCOP00000000784	Ig-like domain-containing protein. (201 aa)
	Hdlbp	High density lipoprotein binding protein a. (1257 aa)
	ENSXCOP00000001574	Cubilin (intrinsic factor-cobalamin receptor). (3019 aa)
	ENSXCOP00000002249	High density lipoprotein binding protein b. (1172 aa)
	ENSXCOP00000003875	Uncharacterized protein. (1620 aa)
	ENSXCOP00000003894	Uncharacterized protein. (1601 aa)
	ENSXCOP00000008614	Very low density lipoprotein receptor. (818 aa)
	LOC114141610	Apolipoprotein Eb. (265 aa)
	Apoc1	Uncharacterized protein. (83 aa)
	ENSXCOP00000010072	Adaptin_N domain-containing protein. (247 aa)
	ENSXCOP00000010079	Adaptor related protein complex 2 subunit alpha 1. (307 aa)
	ENSXCOP00000010318	Lipolysis stimulated lipoprotein receptor. (566 aa)
	LOC114153742	AP complex subunit beta. (939 aa)
	Ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
	ENSXCOP00000011552	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (666 aa)
	Npc2	Niemann-Pick disease, type C2. (158 aa)
	ENSXCOP00000013024	Adaptin_N domain-containing protein. (120 aa)
	Amn	Amnion associated transmembrane protein. (465 aa)
	Soat1	O-acyltransferase. (493 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Amn	Cdcp2	ENSXCOP00000014146	ENSXCOP00000025347	Amnion associated transmembrane protein.	CUB domain containing protein 2.	0.901
Amn	ENSXCOP00000001574	ENSXCOP00000014146	ENSXCOP00000001574	Amnion associated transmembrane protein.	Cubilin (intrinsic factor-cobalamin receptor).	0.869
Amn	ENSXCOP00000025344	ENSXCOP00000014146	ENSXCOP00000025344	Amnion associated transmembrane protein.	CUB domain-containing protein.	0.901
Ap2m1	Ap2s1	ENSXCOP00000010657	ENSXCOP00000016796	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
Ap2m1	ENSXCOP00000004323	ENSXCOP00000010657	ENSXCOP00000004323	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Low density lipoprotein receptor adaptor protein 1a.	0.589
Ap2m1	ENSXCOP00000004811	ENSXCOP00000010657	ENSXCOP00000004811	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Apolipoprotein Bb, tandem duplicate 2.	0.459
Ap2m1	ENSXCOP00000008614	ENSXCOP00000010657	ENSXCOP00000008614	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Very low density lipoprotein receptor.	0.462
Ap2m1	ENSXCOP00000010072	ENSXCOP00000010657	ENSXCOP00000010072	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Adaptin_N domain-containing protein.	0.998
Ap2m1	ENSXCOP00000010079	ENSXCOP00000010657	ENSXCOP00000010079	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Adaptor related protein complex 2 subunit alpha 1.	0.987
Ap2m1	ENSXCOP00000013024	ENSXCOP00000010657	ENSXCOP00000013024	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Adaptin_N domain-containing protein.	0.996
Ap2m1	ENSXCOP00000017748	ENSXCOP00000010657	ENSXCOP00000017748	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Apolipoprotein Ba.	0.459
Ap2m1	ENSXCOP00000017948	ENSXCOP00000010657	ENSXCOP00000017948	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Low density lipoprotein receptor b.	0.452
Ap2m1	ENSXCOP00000019705	ENSXCOP00000010657	ENSXCOP00000019705	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.901
Ap2m1	ENSXCOP00000023803	ENSXCOP00000010657	ENSXCOP00000023803	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Alpha_adaptinC2 domain-containing protein.	0.974
Ap2m1	LOC114138068	ENSXCOP00000010657	ENSXCOP00000004814	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Ribosomal protein S27a.	0.695
Ap2m1	LOC114149001	ENSXCOP00000010657	ENSXCOP00000023106	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Ubiquitin-like domain-containing protein.	0.615
Ap2m1	LOC114153742	ENSXCOP00000010657	ENSXCOP00000010375	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit beta.	0.997
Ap2m1	Ldlrap1	ENSXCOP00000010657	ENSXCOP00000014916	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Low density lipoprotein receptor adaptor protein 1b.	0.769
Ap2m1	uba52	ENSXCOP00000010657	ENSXCOP00000007438	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.615
Ap2s1	Ap2m1	ENSXCOP00000016796	ENSXCOP00000010657	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.999