46 items (Xiphophorus couchianus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ENSXCOP00000018754	Pericentrin. (3188 aa)
	ENSXCOP00000019086	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa)
	LOC114140352	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	ENSXCOP00000019266	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (416 aa)
	ENSXCOP00000019312	Tubulin domain-containing protein. (134 aa)
	TUBB2B	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa)
	ENSXCOP00000020638	Uncharacterized protein. (154 aa)
	ENSXCOP00000021041	Tubulin domain-containing protein. (82 aa)
	ENSXCOP00000021821	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
	ENSXCOP00000022630	Histone deacetylase 6. (535 aa)
	ENSXCOP00000022695	ADP-ribosylation factor-like 13b. (369 aa)
	ENSXCOP00000022899	Vimentin like; Belongs to the intermediate filament family. (455 aa)
	LOC114149001	Ubiquitin-like domain-containing protein. (77 aa)
	ENSXCOP00000023119	Tubulin domain-containing protein. (134 aa)
	ENSXCOP00000024534	Intraflagellar transport 88 homolog. (803 aa)
	ENSXCOP00000025624	Dynein, cytoplasmic 1, intermediate chain 2a. (543 aa)
	AKAP9	A-kinase anchoring protein 9. (2538 aa)
	ENSXCOP00000027006	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (426 aa)
	ENSXCOP00000027383	KxDL motif containing 1. (193 aa)
	ENSXCOP00000027432	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (483 aa)
	Ube2n	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
	ENSXCOP00000000595	Uncharacterized protein. (108 aa)
	DYNC1I1	WD_REPEATS_REGION domain-containing protein. (289 aa)
	LOC114154720	Dynein light chain. (89 aa)
	Dync1li2	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (474 aa)
	LOC114138068	Ribosomal protein S27a. (156 aa)
	ENSXCOP00000006606	Parkin RBR E3 ubiquitin protein ligase. (259 aa)
	ENSXCOP00000006612	Ubiquitin-like domain-containing protein. (131 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ENSXCOP00000007455	Tubulin_C domain-containing protein. (119 aa)
	ENSXCOP00000008153	Tubulin, epsilon 1. (263 aa)
	ENSXCOP00000010046	Tubulin domain-containing protein. (104 aa)
	ENSXCOP00000010501	Tubulin domain-containing protein. (82 aa)
	Tubb4b	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (443 aa)
	Cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (995 aa)
	LOC114161559	Dynein light chain. (89 aa)
	ENSXCOP00000014098	Tubulin_C domain-containing protein. (160 aa)
	ENSXCOP00000014249	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
	LOC114160209	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	ENSXCOP00000014756	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (431 aa)
	ENSXCOP00000016118	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (487 aa)
	TUBA4A	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (479 aa)
	ENSXCOP00000017917	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (282 aa)
	park7	Parkinson protein 7. (189 aa)
	ENSXCOP00000018456	Tubulin domain-containing protein. (135 aa)
	LOC114161189	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (155 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP9	Dync1li2	ENSXCOP00000026586	ENSXCOP00000004089	A-kinase anchoring protein 9.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.556
AKAP9	ENSXCOP00000006606	ENSXCOP00000026586	ENSXCOP00000006606	A-kinase anchoring protein 9.	Parkin RBR E3 ubiquitin protein ligase.	0.481
AKAP9	ENSXCOP00000006612	ENSXCOP00000026586	ENSXCOP00000006612	A-kinase anchoring protein 9.	Ubiquitin-like domain-containing protein.	0.481
AKAP9	ENSXCOP00000020638	ENSXCOP00000026586	ENSXCOP00000020638	A-kinase anchoring protein 9.	Uncharacterized protein.	0.625
AKAP9	ENSXCOP00000022695	ENSXCOP00000026586	ENSXCOP00000022695	A-kinase anchoring protein 9.	ADP-ribosylation factor-like 13b.	0.598
AKAP9	ENSXCOP00000024534	ENSXCOP00000026586	ENSXCOP00000024534	A-kinase anchoring protein 9.	Intraflagellar transport 88 homolog.	0.645
AKAP9	ENSXCOP00000027006	ENSXCOP00000026586	ENSXCOP00000027006	A-kinase anchoring protein 9.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.556
AKAP9	LOC114138068	ENSXCOP00000026586	ENSXCOP00000004814	A-kinase anchoring protein 9.	Ribosomal protein S27a.	0.490
AKAP9	LOC114154720	ENSXCOP00000026586	ENSXCOP00000002656	A-kinase anchoring protein 9.	Dynein light chain.	0.557
AKAP9	LOC114161189	ENSXCOP00000026586	ENSXCOP00000018478	A-kinase anchoring protein 9.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.479
AKAP9	LOC114161559	ENSXCOP00000026586	ENSXCOP00000013214	A-kinase anchoring protein 9.	Dynein light chain.	0.557
AKAP9	Ube2n	ENSXCOP00000026586	ENSXCOP00000027445	A-kinase anchoring protein 9.	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.479
AKAP9	park7	ENSXCOP00000026586	ENSXCOP00000017939	A-kinase anchoring protein 9.	Parkinson protein 7.	0.452
Cftr	Dync1li2	ENSXCOP00000011890	ENSXCOP00000004089	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.497
Cftr	ENSXCOP00000006606	ENSXCOP00000011890	ENSXCOP00000006606	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Parkin RBR E3 ubiquitin protein ligase.	0.533
Cftr	ENSXCOP00000006612	ENSXCOP00000011890	ENSXCOP00000006612	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Ubiquitin-like domain-containing protein.	0.533
Cftr	ENSXCOP00000020638	ENSXCOP00000011890	ENSXCOP00000020638	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Uncharacterized protein.	0.459
Cftr	ENSXCOP00000022695	ENSXCOP00000011890	ENSXCOP00000022695	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	ADP-ribosylation factor-like 13b.	0.532
Cftr	ENSXCOP00000024534	ENSXCOP00000011890	ENSXCOP00000024534	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Intraflagellar transport 88 homolog.	0.516
Cftr	ENSXCOP00000027006	ENSXCOP00000011890	ENSXCOP00000027006	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.497