STRINGSTRING
Mtor Mtor map2k1 map2k1 ENSXCOP00000000437 ENSXCOP00000000437 Grb2 Grb2 LOC114136974 LOC114136974 ENSXCOP00000001113 ENSXCOP00000001113 Clip1 Clip1 Wnt10b Wnt10b ENSXCOP00000002143 ENSXCOP00000002143 LOC114161603 LOC114161603 LOC114142532 LOC114142532 ENSXCOP00000002519 ENSXCOP00000002519 ENSXCOP00000002727 ENSXCOP00000002727 wdr24 wdr24 Pdpk1 Pdpk1 Mlst8 Mlst8 ENSXCOP00000004755 ENSXCOP00000004755 Fzd8 Fzd8 LOC114152040 LOC114152040 Sos2 Sos2 ENSXCOP00000005521 ENSXCOP00000005521 Cab39 Cab39 ENSXCOP00000006270 ENSXCOP00000006270 Rps6ka1 Rps6ka1 Slc3a2 Slc3a2 Pik3cb Pik3cb SGK1 SGK1 ENSXCOP00000007091 ENSXCOP00000007091 Lrp5 Lrp5 ENSXCOP00000007266 ENSXCOP00000007266 Ddit4 Ddit4 RRAGA RRAGA ENSXCOP00000008237 ENSXCOP00000008237 lamtor5 lamtor5 Wnt1 Wnt1 Depdc5 Depdc5 Lpin1 Lpin1 ATP6V1A ATP6V1A Mios Mios LOC114153166 LOC114153166 LOC114141391 LOC114141391 LOC114152015 LOC114152015 PIK3CA PIK3CA rragc rragc Slc7a5 Slc7a5 ENSXCOP00000010422 ENSXCOP00000010422 ENSXCOP00000010460 ENSXCOP00000010460 ENSXCOP00000010846 ENSXCOP00000010846 Stk11 Stk11 ENSXCOP00000010985 ENSXCOP00000010985 prkaa2 prkaa2 Wnt4 Wnt4 Lamtor3 Lamtor3 atp6v1a atp6v1a map2k2 map2k2 prkaa1 prkaa1 WNT7A WNT7A ENSXCOP00000013271 ENSXCOP00000013271 ENSXCOP00000013488 ENSXCOP00000013488 ENSXCOP00000013732 ENSXCOP00000013732 ENSXCOP00000013734 ENSXCOP00000013734 SOS1 SOS1 Mapk1 Mapk1 Nprl3 Nprl3 Akt1 Akt1 ENSXCOP00000014725 ENSXCOP00000014725 Rps6ka6 Rps6ka6 Lpin2 Lpin2 Lrp6 Lrp6 ENSXCOP00000015859 ENSXCOP00000015859 ENSXCOP00000016323 ENSXCOP00000016323 ENSXCOP00000016600 ENSXCOP00000016600 LOC114139127 LOC114139127 LOC114138594 LOC114138594 ENSXCOP00000016824 ENSXCOP00000016824 Lamtor1 Lamtor1 Fzd9 Fzd9 LOC114137526 LOC114137526 ENSXCOP00000017651 ENSXCOP00000017651 ENSXCOP00000017812 ENSXCOP00000017812 ENSXCOP00000017838 ENSXCOP00000017838 Nprl2 Nprl2 Eif4e Eif4e Sec13 Sec13 ENSXCOP00000018934 ENSXCOP00000018934 Dvl1 Dvl1 FZD7 FZD7 Wnt6 Wnt6 ENSXCOP00000019552 ENSXCOP00000019552 PRKCA PRKCA ENSXCOP00000019930 ENSXCOP00000019930 Wnt3a Wnt3a Lamtor4 Lamtor4 atp6v1f atp6v1f Fzd10 Fzd10 Rps6ka3 Rps6ka3 ENSXCOP00000021088 ENSXCOP00000021088 ATP6V1B2 ATP6V1B2 ENSXCOP00000021922 ENSXCOP00000021922 ENSXCOP00000022335 ENSXCOP00000022335 Fzd6 Fzd6 Seh1l Seh1l ENSXCOP00000022978 ENSXCOP00000022978 LOC114155135 LOC114155135 Strada Strada Pik3r1 Pik3r1 PRKCB PRKCB ENSXCOP00000024246 ENSXCOP00000024246 LOC114160036 LOC114160036 ENSXCOP00000024825 ENSXCOP00000024825 Insr Insr ENSXCOP00000025146 ENSXCOP00000025146 ENSXCOP00000025182 ENSXCOP00000025182 Gsk3b Gsk3b LOC114139694 LOC114139694 Rheb Rheb ENSXCOP00000026929 ENSXCOP00000026929 ENSXCOP00000026982 ENSXCOP00000026982 ENSXCOP00000027158 ENSXCOP00000027158 ENSXCOP00000027160 ENSXCOP00000027160 Prr5 Prr5 KRAS KRAS Hras Hras ENSXCOP00000028003 ENSXCOP00000028003
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MtorMechanistic target of rapamycin kinase. (922 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
ENSXCOP00000000437Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (453 aa)
Grb2Growth factor receptor-bound protein 2b. (210 aa)
LOC114136974V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ENSXCOP00000001113Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (445 aa)
Clip1Uncharacterized protein. (321 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (427 aa)
ENSXCOP00000002143Si:ch73-335l21.1. (1263 aa)
LOC114161603Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC114142532Uncharacterized protein. (193 aa)
ENSXCOP00000002519Growth factor receptor-bound protein 10a. (557 aa)
ENSXCOP00000002727IlGF domain-containing protein. (187 aa)
wdr24WD repeat domain 24. (783 aa)
Pdpk13-phosphoinositide dependent protein kinase 1b. (538 aa)
Mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (349 aa)
ENSXCOP00000004755TBC1 domain family, member 7. (291 aa)
Fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
LOC114152040Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Sos2Son of sevenless homolog 2 (Drosophila). (1142 aa)
ENSXCOP00000005521Uncharacterized protein. (528 aa)
Cab39Calcium binding protein 39. (338 aa)
ENSXCOP00000006270Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (501 aa)
Rps6ka1Non-specific serine/threonine protein kinase. (681 aa)
Slc3a2Zgc:158423. (475 aa)
Pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (420 aa)
ENSXCOP00000007091Solute carrier family 3 member 2b. (543 aa)
Lrp5Low density lipoprotein receptor-related protein 5. (1602 aa)
ENSXCOP00000007266Protein kinase C, beta a. (287 aa)
Ddit4DNA-damage-inducible transcript 4. (247 aa)
RRAGARas related GTP binding A. (97 aa)
ENSXCOP00000008237Uncharacterized protein. (408 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (104 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
Depdc5Uncharacterized protein. (178 aa)
Lpin1Si:ch73-21k16.1. (867 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
MiosMissing oocyte, meiosis regulator, homolog (Drosophila). (867 aa)
LOC114153166Uncharacterized protein. (193 aa)
LOC114141391Uncharacterized protein. (461 aa)
LOC114152015Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
rragcRas-related GTP binding Ca. (382 aa)
Slc7a5Solute carrier family 7 member 5. (157 aa)
ENSXCOP00000010422Uncharacterized protein. (200 aa)
ENSXCOP00000010460Uncharacterized protein. (192 aa)
ENSXCOP00000010846Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (944 aa)
Stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
ENSXCOP00000010985V-akt murine thymoma viral oncogene homolog 3b; Belongs to the protein kinase superfamily. (498 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
atp6v1aATPase H+ transporting V1 subunit A. (617 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (309 aa)
ENSXCOP00000013271Cytosolic arginine sensor for mTORC1 subunit 1. (37 aa)
ENSXCOP00000013488Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (386 aa)
ENSXCOP00000013732Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
ENSXCOP00000013734Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (615 aa)
Mapk1Mitogen-activated protein kinase. (357 aa)
Nprl3NPR3-like, GATOR1 complex subunit. (469 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (442 aa)
ENSXCOP00000014725Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (329 aa)
Rps6ka6Non-specific serine/threonine protein kinase. (694 aa)
Lpin2Lipin_N domain-containing protein. (112 aa)
Lrp6Uncharacterized protein. (436 aa)
ENSXCOP00000015859Component of inhibitor of nuclear factor kappa B kinase complex. (701 aa)
ENSXCOP00000016323Lipin_N domain-containing protein. (132 aa)
ENSXCOP00000016600Uncharacterized protein. (453 aa)
LOC114139127Calcium binding protein 39, like 1. (343 aa)
LOC114138594Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (230 aa)
ENSXCOP00000016824Uncharacterized protein. (448 aa)
Lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (157 aa)
Fzd9Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
LOC114137526Uncharacterized protein. (216 aa)
ENSXCOP00000017651V-akt murine thymoma viral oncogene homolog 3a. (162 aa)
ENSXCOP00000017812Uncharacterized protein. (113 aa)
ENSXCOP00000017838Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
Nprl2NPR2 like, GATOR1 complex subunit. (343 aa)
Eif4eEukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (194 aa)
Sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
ENSXCOP00000018934Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (472 aa)
Dvl1DIX domain-containing protein. (82 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (579 aa)
Wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (148 aa)
ENSXCOP00000019552Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (114 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (663 aa)
ENSXCOP00000019930Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
Wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (290 aa)
Lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (98 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
Fzd10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
Rps6ka3Ribosomal protein S6 kinase, polypeptide 3b. (312 aa)
ENSXCOP00000021088Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (538 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (469 aa)
ENSXCOP00000021922Lipin 2. (794 aa)
ENSXCOP00000022335Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Fzd6FZ domain-containing protein. (126 aa)
Seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (357 aa)
ENSXCOP00000022978FZ domain-containing protein. (220 aa)
LOC114155135Uncharacterized protein. (119 aa)
StradaSTE20 related adaptor alpha. (259 aa)
Pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (521 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
ENSXCOP00000024246Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (407 aa)
LOC114160036Zgc:55558. (187 aa)
ENSXCOP00000024825Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (576 aa)
InsrTyrosine-protein kinase receptor. (1334 aa)
ENSXCOP00000025146Si:ch211-195b13.1; Belongs to the protein kinase superfamily. (285 aa)
ENSXCOP00000025182Uncharacterized protein. (285 aa)
Gsk3bGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (423 aa)
LOC114139694Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
RhebRas homolog, mTORC1 binding. (189 aa)
ENSXCOP00000026929V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (248 aa)
ENSXCOP00000026982Sestrin 2. (425 aa)
ENSXCOP00000027158Tyrosine-protein kinase receptor. (1403 aa)
ENSXCOP00000027160Calcium binding protein 39-like. (297 aa)
Prr5Proline rich 5a (renal). (406 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
HrasHRas proto-oncogene, GTPase a. (201 aa)
ENSXCOP00000028003Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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