65 items (Xiphophorus couchianus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
	LOC114140865	Tyrosine-protein kinase. (527 aa)
	Grb2	Growth factor receptor-bound protein 2b. (210 aa)
	ENSXCOP00000000821	Matrix metallopeptidase 14a (membrane-inserted). (563 aa)
	Map3k2	Protein kinase domain-containing protein. (137 aa)
	ENSXCOP00000001533	Mitogen-activated protein kinase. (420 aa)
	LOC114154374	Uncharacterized protein. (359 aa)
	Adcy3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
	ENSXCOP00000002875	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (289 aa)
	Mapk10	Mitogen-activated protein kinase. (384 aa)
	Prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (333 aa)
	Cacna1d	Ion_trans domain-containing protein. (212 aa)
	GNAS	GNAS complex locus. (379 aa)
	LOC114139131	Mitogen-activated protein kinase. (420 aa)
	ENSXCOP00000004781	Adenylate cyclase 1a; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (348 aa)
	ENSXCOP00000004885	Protein kinase domain-containing protein. (209 aa)
	Sos2	Son of sevenless homolog 2 (Drosophila). (1142 aa)
	Cga	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (133 aa)
	Itpr1	Inositol 1,4,5-trisphosphate receptor, type 1b. (993 aa)
	ENSXCOP00000006465	Uncharacterized protein. (75 aa)
	ENSXCOP00000007266	Protein kinase C, beta a. (287 aa)
	ENSXCOP00000011147	Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family. (200 aa)
	Jun	BZIP domain-containing protein; Belongs to the bZIP family. (329 aa)
	Pla2g4a	Phospholipase A2. (750 aa)
	LOC114139518	Heparin-binding EGF-like growth factor a. (236 aa)
	ENSXCOP00000012398	ETS domain-containing protein. (233 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	ENSXCOP00000012939	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (91 aa)
	ENSXCOP00000013460	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (328 aa)
	Gnrh2	Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (96 aa)
	ENSXCOP00000013776	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
	Adcy5	AC_N domain-containing protein. (440 aa)
	ENSXCOP00000014275	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (303 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (615 aa)
	Mapk1	Mitogen-activated protein kinase. (357 aa)
	ENSXCOP00000015339	Mitogen-activated protein kinase. (353 aa)
	ENSXCOP00000015874	Mitogen-activated protein kinase. (384 aa)
	Adcy7	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (476 aa)
	ENSXCOP00000018453	GNAS complex locus. (378 aa)
	LOC114142578	Cys_knot domain-containing protein. (113 aa)
	CDC42	Cell division cycle 42. (191 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (663 aa)
	ENSXCOP00000019943	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
	LOC114146401	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	ENSXCOP00000020402	Uncharacterized protein. (98 aa)
	ENSXCOP00000021206	Activating transcription factor 4a. (426 aa)
	Egfr	Receptor protein-tyrosine kinase. (1206 aa)
	SRC	Tyrosine-protein kinase. (559 aa)
	ENSXCOP00000022099	Uncharacterized protein. (272 aa)
	Map3k3	Mitogen-activated protein kinase kinase kinase 3. (620 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
	ENSXCOP00000024246	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (407 aa)
	ENSXCOP00000024310	G_PROTEIN_RECEP_F1_2 domain-containing protein. (189 aa)
	LOC114160036	Zgc:55558. (187 aa)
	Calml4	Calmodulin-like 4a. (117 aa)
	ENSXCOP00000024535	CaMKII_AD domain-containing protein. (146 aa)
	ENSXCOP00000024620	Mitogen-activated protein kinase 14b. (103 aa)
	ENSXCOP00000025011	Inositol 1,4,5-trisphosphate receptor, type 1a. (2683 aa)
	ENSXCOP00000025535	Uncharacterized protein. (196 aa)
	LOC114142284	Uncharacterized protein. (191 aa)
	Prkcd	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
	ENSXCOP00000027173	Focal_AT domain-containing protein. (127 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	Hras	HRas proto-oncogene, GTPase a. (201 aa)
	ENSXCOP00000027767	G_PROTEIN_RECEP_F1_2 domain-containing protein. (91 aa)

Your Current Organism:

Xiphophorus couchianus

NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adcy3	Calml4	ENSXCOP00000002841	ENSXCOP00000024394	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like 4a.	0.912
Adcy3	ENSXCOP00000004781	ENSXCOP00000002841	ENSXCOP00000004781	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 1a; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.406
Adcy3	ENSXCOP00000011147	ENSXCOP00000002841	ENSXCOP00000011147	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family.	0.920
Adcy3	ENSXCOP00000014275	ENSXCOP00000002841	ENSXCOP00000014275	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.437
Adcy3	ENSXCOP00000018453	ENSXCOP00000002841	ENSXCOP00000018453	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.960
Adcy3	GNAS	ENSXCOP00000002841	ENSXCOP00000004157	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.960
Adcy3	LOC114146401	ENSXCOP00000002841	ENSXCOP00000019991	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.921
Adcy3	Map3k2	ENSXCOP00000002841	ENSXCOP00000001097	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase domain-containing protein.	0.516
Adcy3	Prkacb	ENSXCOP00000002841	ENSXCOP00000003931	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.921
Adcy5	Adcy7	ENSXCOP00000013835	ENSXCOP00000016848	AC_N domain-containing protein.	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.513
Adcy5	ENSXCOP00000018453	ENSXCOP00000013835	ENSXCOP00000018453	AC_N domain-containing protein.	GNAS complex locus.	0.959
Adcy5	GNAS	ENSXCOP00000013835	ENSXCOP00000004157	AC_N domain-containing protein.	GNAS complex locus.	0.959
Adcy5	LOC114146401	ENSXCOP00000013835	ENSXCOP00000019991	AC_N domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.919
Adcy5	Prkacb	ENSXCOP00000013835	ENSXCOP00000003931	AC_N domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.919
Adcy7	Adcy5	ENSXCOP00000016848	ENSXCOP00000013835	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	AC_N domain-containing protein.	0.513
Adcy7	ENSXCOP00000018453	ENSXCOP00000016848	ENSXCOP00000018453	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	GNAS complex locus.	0.952
Adcy7	GNAS	ENSXCOP00000016848	ENSXCOP00000004157	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	GNAS complex locus.	0.952
Adcy7	LOC114146401	ENSXCOP00000016848	ENSXCOP00000019991	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.916
Adcy7	Prkacb	ENSXCOP00000016848	ENSXCOP00000003931	Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.916
CDC42	ENSXCOP00000001533	ENSXCOP00000018921	ENSXCOP00000001533	Cell division cycle 42.	Mitogen-activated protein kinase.	0.501