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Ppha_0094 Ppha_0094 Ppha_0099 Ppha_0099 Ppha_0116 Ppha_0116 vapC vapC Ppha_0155 Ppha_0155 pheS pheS thrS thrS Ppha_0182 Ppha_0182 vapC-2 vapC-2 rnc rnc tsaD tsaD Ppha_0234 Ppha_0234 rpoA rpoA rsmG rsmG cysS cysS Ppha_0337 Ppha_0337 miaB miaB Ppha_0385 Ppha_0385 hisS hisS nusA nusA rbfA rbfA truB truB Ppha_0403 Ppha_0403 Ppha_0405 Ppha_0405 Ppha_0420 Ppha_0420 rho rho Ppha_1048 Ppha_1048 proS proS Ppha_1155 Ppha_1155 Ppha_1157 Ppha_1157 rsmA rsmA Ppha_1191 Ppha_1191 metG metG miaA miaA Ppha_1207 Ppha_1207 Ppha_1213 Ppha_1213 trmB trmB Ppha_1272 Ppha_1272 Ppha_1394 Ppha_1394 Ppha_1396 Ppha_1396 Ppha_1406 Ppha_1406 Ppha_1408 Ppha_1408 Ppha_1443 Ppha_1443 trmD trmD rimM rimM rlmN rlmN priA priA truA truA Ppha_1554 Ppha_1554 Ppha_1588 Ppha_1588 aspS aspS cas2 cas2 Ppha_1720 Ppha_1720 Ppha_1723 Ppha_1723 trmH trmH ybeY ybeY lysS lysS tgt tgt rimO rimO fmt fmt Ppha_1792 Ppha_1792 Ppha_1798 Ppha_1798 rnr rnr Ppha_1917 Ppha_1917 rny rny pheT pheT Ppha_2100 Ppha_2100 Ppha_2119 Ppha_2119 Ppha_2124 Ppha_2124 Ppha_2152 Ppha_2152 Ppha_2182 Ppha_2182 Ppha_2183 Ppha_2183 Ppha_2242 Ppha_2242 Ppha_2251 Ppha_2251 Ppha_2257 Ppha_2257 ileS ileS Ppha_2315 Ppha_2315 Ppha_2316 Ppha_2316 Ppha_2317 Ppha_2317 Ppha_2322 Ppha_2322 Ppha_2324 Ppha_2324 Ppha_2380 Ppha_2380 valS valS Ppha_2419 Ppha_2419 cas2-2 cas2-2 mnmA mnmA Ppha_2464 Ppha_2464 Ppha_2486 Ppha_2486 Ppha_2492 Ppha_2492 Ppha_0991 Ppha_0991 Ppha_0985 Ppha_0985 Ppha_0979 Ppha_0979 serS serS Ppha_0928 Ppha_0928 deaD deaD Ppha_0896 Ppha_0896 tyrS tyrS Ppha_0790 Ppha_0790 Ppha_2504 Ppha_2504 Ppha_2560 Ppha_2560 Ppha_2586 Ppha_2586 Ppha_2606 Ppha_2606 Ppha_2636 Ppha_2636 Ppha_2650 Ppha_2650 alaS alaS rpoC rpoC rpoB rpoB nusG nusG vapC-3 vapC-3 mnmE mnmE Ppha_2791 Ppha_2791 Ppha_2805 Ppha_2805 tadA tadA Ppha_0757 Ppha_0757 dnaG dnaG Ppha_0706 Ppha_0706 tilS tilS Ppha_0696 Ppha_0696 rsmI rsmI pnp pnp leuS leuS Ppha_0608 Ppha_0608 nusB nusB Ppha_0499 Ppha_0499 Ppha_0497 Ppha_0497 Ppha_0489 Ppha_0489 gltX gltX Ppha_0459 Ppha_0459 Ppha_0441 Ppha_0441 Ppha_2822 Ppha_2822 Ppha_2866 Ppha_2866 Ppha_2877 Ppha_2877 argS argS rsmH rsmH Ppha_2909 Ppha_2909 rnpA rnpA mnmG mnmG rnhB rnhB Ppha_0025 Ppha_0025 glyQS glyQS Ppha_0090 Ppha_0090 Ppha_0091 Ppha_0091
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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Ppha_0094KEGG: syn:sll1715 hypothetical protein. (135 aa)
Ppha_0099PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cph:Cpha266_0756 PHP C-terminal domain protein. (233 aa)
Ppha_0116KEGG: cph:Cpha266_0798 RNA polymerase, sigma-24 subunit, ECF subfamily. (144 aa)
vapCPilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (137 aa)
Ppha_0155PFAM: protein of unknown function DUF891; KEGG: plt:Plut_0606 hypothetical protein. (116 aa)
pheSTIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; KEGG: cph:Cpha266_2505 phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (342 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (657 aa)
Ppha_0182TIGRFAM: prevent-host-death family protein; KEGG: gur:Gura_3866 prevent-host-death family protein. (116 aa)
vapC-2PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (125 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (273 aa)
tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (350 aa)
Ppha_0234KEGG: cph:Cpha266_0798 RNA polymerase, sigma-24 subunit, ECF subfamily. (153 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (327 aa)
rsmGMethyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (228 aa)
cysSKEGG: pvi:Cvib_0277 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (484 aa)
Ppha_0337Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (247 aa)
miaBRNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (440 aa)
Ppha_0385KEGG: pvi:Cvib_0686 hypothetical protein. (109 aa)
hisSKEGG: cte:CT0236 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (429 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (514 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (119 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (241 aa)
Ppha_0403PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cch:Cag_1457 hypothetical protein. (295 aa)
Ppha_0405KEGG: plt:Plut_1772 hypothetical protein. (117 aa)
Ppha_0420PFAM: PilT protein domain protein; KEGG: mar:MAE_40120 PilT-like protein. (137 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (429 aa)
Ppha_1048PFAM: PilT protein domain protein; KEGG: cch:Cag_1777 PIN (PilT N terminus) domain. (109 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (481 aa)
Ppha_1155RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: plt:Plut_1207 sigma-24 (FecI-like). (150 aa)
Ppha_1157PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: cph:Cpha266_1411 tRNA/rRNA methyltransferase (SpoU). (180 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (262 aa)
Ppha_1191PFAM: Protein of unknown function methylase putative; KEGG: cph:Cpha266_1016 conserved hypothetical protein 95. (178 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (700 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (318 aa)
Ppha_1207TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: cch:Cag_0781 sigma-54 factor. (482 aa)
Ppha_1213PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: cch:Cag_0722 HDIG; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (479 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (204 aa)
Ppha_1272TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: cph:Cpha266_1376 addiction module toxin, RelE/StbE family. (86 aa)
Ppha_1394PFAM: RNP-1 like RNA-binding protein; KEGG: cph:Cpha266_1273 RNP-1 like RNA-binding protein. (95 aa)
Ppha_1396PFAM: protein of unknown function DUF86; KEGG: ppd:Ppro_2947 protein of unknown function DUF86. (144 aa)
Ppha_1406KEGG: cph:Cpha266_1292 hypothetical protein. (383 aa)
Ppha_1408PFAM: PilT protein domain protein; KEGG: ava:Ava_0767 PilT protein-like. (127 aa)
Ppha_1443TIGRFAM: addiction module toxin, Txe/YoeB family; addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; Addiction module toxin Txe/YoeB; KEGG: fjo:Fjoh_0231 addiction module toxin, Txe/YoeB family. (92 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (248 aa)
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (173 aa)
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (359 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (812 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (243 aa)
Ppha_1554PFAM: PilT protein domain protein; KEGG: neu:NE2174 hypothetical protein. (125 aa)
Ppha_1588PFAM: protein of unknown function DUF86; KEGG: cph:Cpha266_0768 protein of unknown function DUF86. (138 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (601 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (96 aa)
Ppha_1720PFAM: PilT protein domain protein; KEGG: cch:Cag_0660 hypothetical protein. (129 aa)
Ppha_1723PFAM: protein of unknown function DUF891; KEGG: plt:Plut_0835 conserved hypothetical protein, phage-related. (108 aa)
trmHtRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (212 aa)
ybeYProtein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (139 aa)
lysSTIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: cch:Cag_1176 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (511 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (377 aa)
rimOMiaB-like tRNA modifying enzyme YliG; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (431 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (319 aa)
Ppha_1792TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; KEGG: gur:Gura_1444 addiction module toxin, Txe/YoeB family. (86 aa)
Ppha_1798Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (349 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (770 aa)
Ppha_1917KEGG: cch:Cag_0913 hypothetical protein. (141 aa)
rnyRNA binding metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (524 aa)
pheTKEGG: cph:Cpha266_0925 phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (803 aa)
Ppha_2100PFAM: RNP-1 like RNA-binding protein; KEGG: cch:Cag_1551 RNA-binding region RNP-1 (RNA recognition motif). (90 aa)
Ppha_2119KEGG: cch:Cag_1343 hypothetical protein. (157 aa)
Ppha_2124PFAM: protein of unknown function DUF891; KEGG: cph:Cpha266_0649 protein of unknown function DUF891. (117 aa)
Ppha_2152RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cph:Cpha266_0868 RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (209 aa)
Ppha_2182KEGG: tbd:Tbd_2422 hypothetical protein. (42 aa)
Ppha_2183KEGG: tbd:Tbd_2422 hypothetical protein. (71 aa)
Ppha_2242PFAM: protein of unknown function DUF891; KEGG: eba:ebD106 hypothetical protein, phage-related. (107 aa)
Ppha_2251PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cch:Cag_0481 phosphoesterase PHP-like. (286 aa)
Ppha_2257PFAM: domain of unknown function DUF1730; KEGG: cch:Cag_0255 iron-sulfur cluster-binding protein. (324 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1085 aa)
Ppha_2315TIGRFAM: sulfur relay protein TusB/DsrH; PFAM: DsrH family protein; KEGG: cph:Cpha266_0134 DsrH family protein. (97 aa)
Ppha_2316TIGRFAM: sulfur relay protein TusC/DsrF; PFAM: DsrE family protein; KEGG: cph:Cpha266_0133 DsrE family protein. (129 aa)
Ppha_2317TIGRFAM: sulfur relay protein TusD/DsrE; PFAM: DsrE family protein; KEGG: cph:Cpha266_0132 DsrE family protein. (119 aa)
Ppha_2322TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; KEGG: cch:Cag_1957 sulfite reductase, dissimilatory-type, gamma subunit. (111 aa)
Ppha_2324PFAM: SirA family protein; KEGG: cph:Cpha266_0125 SirA family protein; Belongs to the sulfur carrier protein TusA family. (77 aa)
Ppha_2380RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (299 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (903 aa)
Ppha_2419KEGG: cch:Cag_0316 hypothetical protein. (247 aa)
cas2-2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)
mnmAtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (361 aa)
Ppha_2464KEGG: cph:Cpha266_1809 metal dependent phosphohydrolase. (180 aa)
Ppha_2486PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: pvi:Cvib_0364 YbaK/prolyl-tRNA synthetase associated region. (156 aa)
Ppha_2492PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: cph:Cpha266_2163 tRNA/rRNA methyltransferase (SpoU). (269 aa)
Ppha_0991PFAM: Radical SAM domain protein; KEGG: cch:Cag_0688 MoaA/NifB/PqqE family protein. (311 aa)
Ppha_0985TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: pca:Pcar_1787 hypothetical protein. (85 aa)
Ppha_0979KEGG: cch:Cag_0400 chlorophyllide reductase iron protein subunit X; TIGRFAM: chlorophyllide reductase iron protein subunit X; PFAM: NifH/frxC-family protein; Sigma-70 region 4 type 2; Belongs to the NifH/BchL/ChlL family. (370 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (431 aa)
Ppha_0928Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (445 aa)
deaDDEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (599 aa)
Ppha_0896KEGG: btr:Btr_1076 hypothetical protein. (92 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (405 aa)
Ppha_0790PFAM: protein of unknown function DUF891; KEGG: cph:Cpha266_0649 protein of unknown function DUF891. (117 aa)
Ppha_2504TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: nmu:Nmul_A2035 hypothetical protein. (93 aa)
Ppha_2560TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (352 aa)
Ppha_2586TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: plasmid stabilization system; Addiction module toxin Txe/YoeB; KEGG: plt:Plut_1930 addiction module toxin, Txe/YoeB. (93 aa)
Ppha_2606Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (507 aa)
Ppha_2636KEGG: pna:Pnap_1139 hypothetical protein. (168 aa)
Ppha_2650KEGG: syn:sll1715 hypothetical protein. (140 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (888 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1497 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1303 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (191 aa)
vapC-3PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (134 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (473 aa)
Ppha_2791KEGG: bpd:BURPS668_3905 hypothetical protein. (160 aa)
Ppha_2805Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (145 aa)
tadACMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (155 aa)
Ppha_0757KEGG: ajs:Ajs_3020 hypothetical protein. (146 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (631 aa)
Ppha_0706Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (146 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (328 aa)
Ppha_0696TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: cch:Cag_1731 RNA methyltransferase TrmH, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (248 aa)
rsmIUroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (244 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (728 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: cch:Cag_1688 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (807 aa)
Ppha_0608PFAM: PilT protein domain protein; KEGG: cch:Cag_1292 hypothetical protein. (131 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (171 aa)
Ppha_0499Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (317 aa)
Ppha_0497Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: cch:Cag_0542 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. (247 aa)
Ppha_0489PFAM: protein of unknown function DUF88; KEGG: cph:Cpha266_0482 protein of unknown function DUF88. (287 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (502 aa)
Ppha_0459MiaB-like tRNA modifying enzyme; KEGG: cph:Cpha266_0422 RNA modification enzyme, MiaB family; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB. (453 aa)
Ppha_0441RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cph:Cpha266_0408 RNA polymerase, sigma-24 subunit, ECF subfamily. (180 aa)
Ppha_2822KEGG: cph:Cpha266_2587 hypothetical protein. (420 aa)
Ppha_2866KEGG: ajs:Ajs_3020 hypothetical protein. (147 aa)
Ppha_2877KEGG: cph:Cpha266_2700 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib. (348 aa)
argSKEGG: pvi:Cvib_1732 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (552 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (332 aa)
Ppha_2909TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; KEGG: plt:Plut_2126 23S rRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (488 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (136 aa)
mnmGGlucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (621 aa)
rnhBRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (206 aa)
Ppha_0025TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: cph:Cpha266_0040 ribonuclease, Rne/Rng family. (562 aa)
glyQSglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (491 aa)
Ppha_0090PFAM: protein of unknown function UPF0079; KEGG: cph:Cpha266_2666 protein of unknown function UPF0079. (145 aa)
Ppha_0091PFAM: peptidase M22 glycoprotease; KEGG: cch:Cag_1986 protease, putative. (223 aa)
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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