(103 nodes) Positive regulation of cellular amide metabolic process network (Neolamprologus brichardi)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102789818	Required for meiotic nuclear division 1 homolog. (412 aa)
	LOC102786472	YTH N(6)-methyladenosine RNA binding protein 1. (604 aa)
	LOC102780300	CBP80/20-dependent translation initiation factor. (669 aa)
	LOC102776555	Neugrin, neurite outgrowth associated. (277 aa)
	LOC102783563	Eukaryotic translation initiation factor 2, subunit 3 gamma. (439 aa)
	LOC102777494	Terminal nucleotidyltransferase 4B. (651 aa)
	LOC102799489	La ribonucleoprotein domain family, member 1. (964 aa)
	TENT4A	Terminal nucleotidyltransferase 4A. (498 aa)
	LOC102776587	Lin-28 homolog A. (202 aa)
	LOC102777042	Eukaryotic translation initiation factor 5A. (156 aa)
	LOC102783870	DnaJ (Hsp40) homolog, subfamily C, member 3a. (503 aa)
	LOC102798345	Urotensin 1. (148 aa)
	LOC102779289	Eukaryotic translation initiation factor 5A. (153 aa)
	ENSNBRP00000013046	Uncharacterized protein. (104 aa)
	ENSNBRP00000013058	Ectonucleotide pyrophosphatase/phosphodiesterase 7. (282 aa)
	LOC102777507	Eukaryotic translation initiation factor 4 gamma, 3a. (1466 aa)
	LOC102790932	Nuclear factor, erythroid 2-like 2a. (594 aa)
	LOC102786139	Jumonji domain containing 4. (431 aa)
	LOC102780301	Uncharacterized protein. (193 aa)
	LOC102792734	La ribonucleoprotein domain family, member 4Aa. (809 aa)
	LOC102797929	DEAH (Asp-Glu-Ala-His) box polypeptide 29. (1125 aa)
	ENSNBRP00000014970	UPF3B regulator of nonsense mediated mRNA decay. (206 aa)
	LOC102782862	Fragile X mental retardation, autosomal homolog 2. (672 aa)
	ENSNBRP00000016361	Uncharacterized protein. (140 aa)
	LOC102779255	Methyltransferase like 5. (220 aa)
	LOC102782504	RCC1 like. (409 aa)
	LOC102793467	FAST kinase domains 3. (659 aa)
	ENSNBRP00000018932	IHABP4_N domain-containing protein. (94 aa)
	ENSNBRP00000019350	Zgc:153896. (272 aa)
	ENSNBRP00000019527	Mitochondrial ribosomal protein S27. (269 aa)
	LOC102784398	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (260 aa)
	LOC102776948	Uncharacterized protein. (1590 aa)
	YTHDF1	YTH N6-methyladenosine RNA binding protein 1. (599 aa)
	ENSNBRP00000020427	La ribonucleoprotein domain family, member 4Ab. (347 aa)
	LOC102789593	Proline rich 16. (217 aa)
	LOC102777509	TruB pseudouridine (psi) synthase family member 2. (330 aa)
	LOC102791117	Ephrin-A1a; Belongs to the ephrin family. (224 aa)
	ENSNBRP00000021621	Protein kinase domain-containing protein. (200 aa)
	LOC102788012	Forkhead box A3. (466 aa)
	LOC102789887	U2AF homology motif (UHM) kinase 1. (403 aa)
	LOC102788058	NCK associated protein 5. (1755 aa)
	LOC102792901	Eukaryotic translation initiation factor 2B, subunit 5 epsilon. (708 aa)
	LOC102791240	Cytoplasmic protein. (392 aa)
	ENSNBRP00000023385	tRNA methyltransferase 10C, mitochondrial RNase P subunit. (262 aa)
	LOC102799402	Non-specific serine/threonine protein kinase. (803 aa)
	ENSNBRP00000023592	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (530 aa)
	LOC102790614	Cellular communication network factor 1. (379 aa)
	LOC102786639	Cold inducible RNA binding protein b. (183 aa)
	ENSNBRP00000026030	RRM domain-containing protein. (219 aa)
	LOC102789747	ATP-binding cassette, sub-family F (GCN20), member 1. (514 aa)
	LOC102798531	Impact RWD domain protein. (320 aa)
	LARP4B	La ribonucleoprotein domain family member 4B. (652 aa)
	ENSNBRP00000026510	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2423 aa)
	LOC102781767	Fragile X mental retardation, autosomal homolog 1. (603 aa)
	EIF5AL1	Eukaryotic translation initiation factor 5A. (155 aa)
	LOC102790939	Poly(A) binding protein interacting protein 1. (448 aa)
	LOC102791151	ELAV-like protein; Belongs to the RRM elav family. (343 aa)
	LOC102797887	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (561 aa)
	LOC102779658	CCHC-type zinc finger, nucleic acid binding protein a. (166 aa)
	LOC102779310	Fragile X mental retardation 1. (523 aa)
	LOC102782001	Ubiquinol-cytochrome c reductase complex assembly factor 2. (129 aa)
	LOC102795021	Ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2. (465 aa)
	LOC102789511	YTH N(6)-methyladenosine RNA binding protein 3. (581 aa)
	LOC102798704	La ribonucleoprotein domain family, member 1B. (886 aa)
	LOC102781493	Methyltransferase like 3; Belongs to the MT-A70-like family. (591 aa)
	ENSNBRP00000032023	Cytochrome C oxidase assembly factor 3b. (125 aa)
	ENSNBRP00000032070	Uncharacterized protein. (397 aa)
	LOC102797204	FAST kinase domains 2. (667 aa)
	ENSNBRP00000009257	Uncharacterized protein. (95 aa)
	LOC102776454	Complement component 1, q subcomponent binding protein. (240 aa)
	LOC102795590	La ribonucleoprotein domain family, member 6a. (512 aa)
	LOC102788122	CDK5 regulatory subunit associated protein 1. (562 aa)
	LOC102783656	Terminal nucleotidyltransferase 4A. (418 aa)
	ENSNBRP00000001832	USP domain-containing protein; Belongs to the peptidase C19 family. (102 aa)
	ENSNBRP00000001868	Ubiquitinyl hydrolase 1. (319 aa)
	ENSNBRP00000001997	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (525 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1522 aa)
	LOC102799039	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (896 aa)
	LOC102796373	Polymerase (DNA-directed), delta interacting protein 3. (477 aa)
	LOC102795494	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (497 aa)
	LOC102779006	DnaJ (Hsp40) homolog, subfamily C, member 3b. (471 aa)
	LOC102790447	Zinc finger, CCHC domain containing 4. (443 aa)
	LOC102786442	UPF3A regulator of nonsense mediated mRNA decay. (463 aa)
	LOC102780261	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
	LOC102787645	Si:dkey-103i16.6. (441 aa)
	LOC102788472	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	LOC102784961	Polymerase (RNA) II (DNA directed) polypeptide G-like. (162 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1620 aa)
	ENSNBRP00000004964	Sp1 transcription factor. (470 aa)
	LOC102789704	PTEN induced kinase 1. (574 aa)
	LOC102794784	Cytoplasmic protein. (398 aa)
	LOC102783305	MIF4G domain containing a. (221 aa)
	LOC102776729	Ephrin-A1b; Belongs to the ephrin family. (234 aa)
	ENSNBRP00000006550	Uncharacterized protein; Belongs to the complex I LYR family. (70 aa)
	LOC102792250	Deleted in azoospermia-like. (200 aa)
	LOC102792025	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	LOC102786967	Cytochrome C oxidase assembly factor 3a. (100 aa)
	LOC102799316	ELAV-like protein; Belongs to the RRM elav family. (335 aa)
	LOC102784095	PDX1 C-terminal inhibiting factor 1. (714 aa)
	LOC102784381	PDX1 C-terminal inhibiting factor 1. (725 aa)
	LOC102777374	PYM homolog 1, exon junction complex associated factor. (211 aa)
	LOC102785236	CCHC-type zinc finger, nucleic acid binding protein b. (170 aa)
	ENSNBRP00000009106	Uncharacterized protein. (63 aa)

Your Current Organism:

Neolamprologus brichardi

NCBI taxonomy Id: 32507
Other names: Lamprologus brichardi, N. brichardi, lyretail cichlid

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF2AK4	EIF5AL1	ENSNBRP00000002497	ENSNBRP00000027756	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 5A.	0.419
EIF2AK4	ENSNBRP00000026510	ENSNBRP00000002497	ENSNBRP00000026510	Eukaryotic translation initiation factor 2 alpha kinase 4.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.946
EIF2AK4	LOC102777042	ENSNBRP00000002497	ENSNBRP00000012410	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 5A.	0.419
EIF2AK4	LOC102777509	ENSNBRP00000002497	ENSNBRP00000021265	Eukaryotic translation initiation factor 2 alpha kinase 4.	TruB pseudouridine (psi) synthase family member 2.	0.477
EIF2AK4	LOC102779289	ENSNBRP00000002497	ENSNBRP00000012684	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 5A.	0.419
EIF2AK4	LOC102783563	ENSNBRP00000002497	ENSNBRP00000011504	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.917
EIF2AK4	LOC102788472	ENSNBRP00000002497	ENSNBRP00000004337	Eukaryotic translation initiation factor 2 alpha kinase 4.	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.	0.470
EIF2AK4	LOC102789747	ENSNBRP00000002497	ENSNBRP00000026131	Eukaryotic translation initiation factor 2 alpha kinase 4.	ATP-binding cassette, sub-family F (GCN20), member 1.	0.584
EIF2AK4	LOC102790932	ENSNBRP00000002497	ENSNBRP00000014248	Eukaryotic translation initiation factor 2 alpha kinase 4.	Nuclear factor, erythroid 2-like 2a.	0.853
EIF2AK4	LOC102792901	ENSNBRP00000002497	ENSNBRP00000022604	Eukaryotic translation initiation factor 2 alpha kinase 4.	Eukaryotic translation initiation factor 2B, subunit 5 epsilon.	0.732
EIF2AK4	LOC102798531	ENSNBRP00000002497	ENSNBRP00000002216	Eukaryotic translation initiation factor 2 alpha kinase 4.	Impact RWD domain protein.	0.586
EIF4G1	ENSNBRP00000014970	ENSNBRP00000004961	ENSNBRP00000014970	Eukaryotic translation initiation factor 4 gamma 1.	UPF3B regulator of nonsense mediated mRNA decay.	0.492
EIF4G1	ENSNBRP00000021621	ENSNBRP00000004961	ENSNBRP00000021621	Eukaryotic translation initiation factor 4 gamma 1.	Protein kinase domain-containing protein.	0.719
EIF4G1	ENSNBRP00000026030	ENSNBRP00000004961	ENSNBRP00000026030	Eukaryotic translation initiation factor 4 gamma 1.	RRM domain-containing protein.	0.538
EIF4G1	LOC102776948	ENSNBRP00000004961	ENSNBRP00000019842	Eukaryotic translation initiation factor 4 gamma 1.	Uncharacterized protein.	0.817
EIF4G1	LOC102777507	ENSNBRP00000004961	ENSNBRP00000013440	Eukaryotic translation initiation factor 4 gamma 1.	Eukaryotic translation initiation factor 4 gamma, 3a.	0.574
EIF4G1	LOC102780261	ENSNBRP00000004961	ENSNBRP00000002901	Eukaryotic translation initiation factor 4 gamma 1.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.520
EIF4G1	LOC102783563	ENSNBRP00000004961	ENSNBRP00000011504	Eukaryotic translation initiation factor 4 gamma 1.	Eukaryotic translation initiation factor 2, subunit 3 gamma.	0.790
EIF4G1	LOC102786442	ENSNBRP00000004961	ENSNBRP00000000983	Eukaryotic translation initiation factor 4 gamma 1.	UPF3A regulator of nonsense mediated mRNA decay.	0.492
EIF4G1	LOC102786639	ENSNBRP00000004961	ENSNBRP00000025719	Eukaryotic translation initiation factor 4 gamma 1.	Cold inducible RNA binding protein b.	0.554