21 items (Neolamprologus brichardi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102797708	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (391 aa)
	ENSNBRP00000000656	Fumarate hydratase. (475 aa)
	LOC102797263	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (858 aa)
	LOC102776224	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (331 aa)
	LOC102784039	Dihydrolipoamide S-succinyltransferase. (462 aa)
	LOC102788451	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
	ENSNBRP00000007479	Uncharacterized protein. (113 aa)
	LOC102778223	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (477 aa)
	LOC102789113	Branched chain keto acid dehydrogenase E1 subunit beta. (386 aa)
	OGDH	Oxoglutarate dehydrogenase. (928 aa)
	LOC102785460	Protein-serine/threonine kinase. (428 aa)
	LOC102792349	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
	LOC102793160	Mitochondrial ribosomal protein S36. (111 aa)
	LOC102780018	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (316 aa)
	DLST	Dihydrolipoamide S-succinyltransferase. (236 aa)
	ENSNBRP00000024868	Uncharacterized protein. (76 aa)
	LOC102791286	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (361 aa)
	ENSNBRP00000025801	Oxoglutarate dehydrogenase like. (1002 aa)
	LOC102799484	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
	ENSNBRP00000031576	Uncharacterized protein. (66 aa)
	LOC102778186	Dihydrolipoamide dehydrogenase. (468 aa)

Your Current Organism:

Neolamprologus brichardi

NCBI taxonomy Id: 32507
Other names: Lamprologus brichardi, N. brichardi, lyretail cichlid

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLST	ENSNBRP00000000656	ENSNBRP00000024856	ENSNBRP00000000656	Dihydrolipoamide S-succinyltransferase.	Fumarate hydratase.	0.721
DLST	ENSNBRP00000025801	ENSNBRP00000024856	ENSNBRP00000025801	Dihydrolipoamide S-succinyltransferase.	Oxoglutarate dehydrogenase like.	0.996
DLST	ENSNBRP00000031576	ENSNBRP00000024856	ENSNBRP00000031576	Dihydrolipoamide S-succinyltransferase.	Uncharacterized protein.	0.801
DLST	LOC102776224	ENSNBRP00000024856	ENSNBRP00000004344	Dihydrolipoamide S-succinyltransferase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.854
DLST	LOC102778186	ENSNBRP00000024856	ENSNBRP00000000570	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoamide dehydrogenase.	0.998
DLST	LOC102778223	ENSNBRP00000024856	ENSNBRP00000008831	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.750
DLST	LOC102780018	ENSNBRP00000024856	ENSNBRP00000023395	Dihydrolipoamide S-succinyltransferase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.854
DLST	LOC102784039	ENSNBRP00000024856	ENSNBRP00000004810	Dihydrolipoamide S-succinyltransferase.	Dihydrolipoamide S-succinyltransferase.	0.842
DLST	LOC102785460	ENSNBRP00000024856	ENSNBRP00000014264	Dihydrolipoamide S-succinyltransferase.	Protein-serine/threonine kinase.	0.754
DLST	LOC102788451	ENSNBRP00000024856	ENSNBRP00000005455	Dihydrolipoamide S-succinyltransferase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.990
DLST	LOC102789113	ENSNBRP00000024856	ENSNBRP00000010356	Dihydrolipoamide S-succinyltransferase.	Branched chain keto acid dehydrogenase E1 subunit beta.	0.985
DLST	LOC102791286	ENSNBRP00000024856	ENSNBRP00000025244	Dihydrolipoamide S-succinyltransferase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.801
DLST	LOC102792349	ENSNBRP00000024856	ENSNBRP00000018685	Dihydrolipoamide S-succinyltransferase.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.986
DLST	LOC102793160	ENSNBRP00000024856	ENSNBRP00000022570	Dihydrolipoamide S-succinyltransferase.	Mitochondrial ribosomal protein S36.	0.428
DLST	LOC102797263	ENSNBRP00000024856	ENSNBRP00000004095	Dihydrolipoamide S-succinyltransferase.	Oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide).	0.996
DLST	LOC102797708	ENSNBRP00000024856	ENSNBRP00000019703	Dihydrolipoamide S-succinyltransferase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.801
DLST	LOC102799484	ENSNBRP00000024856	ENSNBRP00000027881	Dihydrolipoamide S-succinyltransferase.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.964
DLST	OGDH	ENSNBRP00000024856	ENSNBRP00000010528	Dihydrolipoamide S-succinyltransferase.	Oxoglutarate dehydrogenase.	0.995
ENSNBRP00000000656	DLST	ENSNBRP00000000656	ENSNBRP00000024856	Fumarate hydratase.	Dihydrolipoamide S-succinyltransferase.	0.721
ENSNBRP00000000656	ENSNBRP00000024868	ENSNBRP00000000656	ENSNBRP00000024868	Fumarate hydratase.	Uncharacterized protein.	0.721