(14 nodes) DHS-like NAD/FAD-binding domain superfamily network (Neolamprologus brichardi)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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co-expression

protein homology

Your Input:
	LOC102787559	ETF domain-containing protein. (277 aa)
	LOC102796760	Sirtuin 7. (405 aa)
	LOC102796672	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (301 aa)
	LOC102776783	Nicotinamide nucleotide transhydrogenase 2. (1017 aa)
	LOC102781225	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (330 aa)
	LOC102797521	Sirtuin 6. (351 aa)
	LOC102785347	IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (625 aa)
	LOC102796801	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (568 aa)
	LOC102794067	Deacetylase sirtuin-type domain-containing protein. (695 aa)
	LOC102784398	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (260 aa)
	LOC102784512	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (325 aa)
	LOC102794989	Deoxyhypusine synthase. (360 aa)
	LOC102787645	Si:dkey-103i16.6. (441 aa)
	LOC102787054	Nicotinamide nucleotide transhydrogenase. (953 aa)

Your Current Organism:

Neolamprologus brichardi

NCBI taxonomy Id: 32507
Other names: Lamprologus brichardi, N. brichardi, lyretail cichlid

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102776783	LOC102781225	ENSNBRP00000029458	ENSNBRP00000029150	Nicotinamide nucleotide transhydrogenase 2.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.841
LOC102776783	LOC102784398	ENSNBRP00000029458	ENSNBRP00000019817	Nicotinamide nucleotide transhydrogenase 2.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.842
LOC102776783	LOC102784512	ENSNBRP00000029458	ENSNBRP00000017260	Nicotinamide nucleotide transhydrogenase 2.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.841
LOC102776783	LOC102787054	ENSNBRP00000029458	ENSNBRP00000000277	Nicotinamide nucleotide transhydrogenase 2.	Nicotinamide nucleotide transhydrogenase.	0.841
LOC102776783	LOC102787645	ENSNBRP00000029458	ENSNBRP00000004123	Nicotinamide nucleotide transhydrogenase 2.	Si:dkey-103i16.6.	0.842
LOC102776783	LOC102794067	ENSNBRP00000029458	ENSNBRP00000021743	Nicotinamide nucleotide transhydrogenase 2.	Deacetylase sirtuin-type domain-containing protein.	0.842
LOC102776783	LOC102796672	ENSNBRP00000029458	ENSNBRP00000030234	Nicotinamide nucleotide transhydrogenase 2.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.841
LOC102776783	LOC102796760	ENSNBRP00000029458	ENSNBRP00000031149	Nicotinamide nucleotide transhydrogenase 2.	Sirtuin 7.	0.845
LOC102776783	LOC102797521	ENSNBRP00000029458	ENSNBRP00000026535	Nicotinamide nucleotide transhydrogenase 2.	Sirtuin 6.	0.841
LOC102781225	LOC102776783	ENSNBRP00000029150	ENSNBRP00000029458	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Nicotinamide nucleotide transhydrogenase 2.	0.841
LOC102781225	LOC102784398	ENSNBRP00000029150	ENSNBRP00000019817	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.936
LOC102781225	LOC102784512	ENSNBRP00000029150	ENSNBRP00000017260	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.917
LOC102781225	LOC102787054	ENSNBRP00000029150	ENSNBRP00000000277	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Nicotinamide nucleotide transhydrogenase.	0.841
LOC102781225	LOC102787645	ENSNBRP00000029150	ENSNBRP00000004123	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Si:dkey-103i16.6.	0.936
LOC102781225	LOC102794067	ENSNBRP00000029150	ENSNBRP00000021743	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Deacetylase sirtuin-type domain-containing protein.	0.915
LOC102781225	LOC102796672	ENSNBRP00000029150	ENSNBRP00000030234	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.915
LOC102781225	LOC102796760	ENSNBRP00000029150	ENSNBRP00000031149	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Sirtuin 7.	0.922
LOC102781225	LOC102797521	ENSNBRP00000029150	ENSNBRP00000026535	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Sirtuin 6.	0.939
LOC102784398	LOC102776783	ENSNBRP00000019817	ENSNBRP00000029458	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	Nicotinamide nucleotide transhydrogenase 2.	0.842
LOC102784398	LOC102781225	ENSNBRP00000019817	ENSNBRP00000029150	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.936