node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sbal_2022 | Sbal_2024 | Sbal_2022 | Sbal_2024 | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | 0.950 |
Sbal_2022 | Sbal_2027 | Sbal_2022 | Sbal_2027 | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: son:SO2440 thiH protein. | 0.988 |
Sbal_2022 | thiE | Sbal_2022 | Sbal_2023 | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
Sbal_2022 | thiG | Sbal_2022 | Sbal_2026 | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.993 |
Sbal_2022 | thiI | Sbal_2022 | Sbal_1362 | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.412 |
Sbal_2024 | Sbal_2022 | Sbal_2024 | Sbal_2022 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | 0.950 |
Sbal_2024 | Sbal_2027 | Sbal_2024 | Sbal_2027 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: son:SO2440 thiH protein. | 0.943 |
Sbal_2024 | iscS | Sbal_2024 | Sbal_2397 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.739 |
Sbal_2024 | thiE | Sbal_2024 | Sbal_2023 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.987 |
Sbal_2024 | thiG | Sbal_2024 | Sbal_2026 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.985 |
Sbal_2024 | thiI | Sbal_2024 | Sbal_1362 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.942 |
Sbal_2027 | Sbal_2022 | Sbal_2027 | Sbal_2022 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: son:SO2440 thiH protein. | KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC. | 0.988 |
Sbal_2027 | Sbal_2024 | Sbal_2027 | Sbal_2024 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: son:SO2440 thiH protein. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein. | 0.943 |
Sbal_2027 | thiE | Sbal_2027 | Sbal_2023 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: son:SO2440 thiH protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.991 |
Sbal_2027 | thiG | Sbal_2027 | Sbal_2026 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: son:SO2440 thiH protein. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
Sbal_2961 | dxs | Sbal_2961 | Sbal_1357 | 1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.916 |
Sbal_2961 | thiE | Sbal_2961 | Sbal_2023 | 1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.426 |
Sbal_2961 | thiG | Sbal_2961 | Sbal_2026 | 1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.918 |
Sbal_2961 | thiI | Sbal_2961 | Sbal_1362 | 1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.442 |
Sbal_3529 | Sbal_3691 | Sbal_3529 | Sbal_3691 | PFAM: Alkaline phosphatase; KEGG: shn:Shewana3_3446 alkaline phosphatase; Belongs to the alkaline phosphatase family. | PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0584 alkaline phosphatase; Belongs to the alkaline phosphatase family. | 0.927 |