(66 nodes) Glycosyltransferase activity network (Xanthomonas axonopodis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mtgA	Peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (248 aa)
	KGE51596.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
	hisF	Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa)
	KGE51277.1	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
	pncB	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (392 aa)
	KGE51229.1	Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (635 aa)
	KGE51160.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (695 aa)
	KGE51102.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
	KGE51103.1	Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
	hisH	Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (200 aa)
	hisG	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (304 aa)
	glgE	Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. (1038 aa)
	glgB	Glycogen branching protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (727 aa)
	tgt	Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa)
	queA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (356 aa)
	upp	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa)
	KGE51460.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
	KGE51412.1	Laccase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (270 aa)
	glgA	Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (527 aa)
	glgB-2	Glycogen branching protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (743 aa)
	KGE53492.1	4-alpha-glucanotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (649 aa)
	trpD	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa)
	opgH	Glucosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (645 aa)
	ftsI	Cell division protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (622 aa)
	ftsW	Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (458 aa)
	murG	UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (430 aa)
	mrdB	Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (372 aa)
	rlpA	Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (470 aa)
	KGE50798.1	Dolichol-phosphate mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
	KGE50799.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
	KGE50809.1	Glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
	KGE50627.1	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (814 aa)
	KGE53205.1	N-glycosyltransferase; Predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
	lgt	Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (296 aa)
	KGE53089.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
	KGE53090.1	ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
	KGE53069.1	Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
	KGE53034.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
	mltG	Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (357 aa)
	KGE52976.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
	KGE52847.1	Hypoxanthine-guanine phosphoribosyltransferase; Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
	KGE52848.1	5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. (250 aa)
	KGE52590.1	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
	KGE52591.1	Hexosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
	pyrE	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (219 aa)
	KGE50898.1	Dolichyl-phosphate-mannose-protein mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
	KGE51273.1	3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (438 aa)
	KGE51299.1	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (808 aa)
	KGE50628.1	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (700 aa)
	KGE50568.1	NdvB protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (799 aa)
	KGE50324.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
	KGE50406.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
	KGE51421.1	Alpha,alpha-trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (455 aa)
	KGE52220.1	Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
	KGE51091.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
	apt	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (186 aa)
	KGE52022.1	Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
	KGE51947.1	Ceramide glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
	KGE51953.1	Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
	KGE51955.1	GDP-mannose:glycolipid 4-beta-D-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
	KGE52390.1	O-antigen biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1166 aa)
	KGE51956.1	Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
	KGE51872.1	Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (295 aa)
	KGE51918.1	Murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
	purF	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (488 aa)
	KGE51660.1	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)

Your Current Organism:

Xanthomonas axonopodis

NCBI taxonomy Id: 325777
Other names: X. axonopodis pv. vasculorum, Xanthomonas axonopodis pv. vasculorum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KGE50406.1	KGE51103.1	GW15_0221885	GW15_0216505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
KGE50627.1	KGE50628.1	GW15_0219395	GW15_0219400	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
KGE50627.1	KGE51103.1	GW15_0219395	GW15_0216505	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.455
KGE50627.1	KGE51299.1	GW15_0219395	GW15_0215275	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.963
KGE50627.1	ftsI	GW15_0219395	GW15_0203280	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Cell division protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.967
KGE50627.1	ftsW	GW15_0219395	GW15_0203300	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.	0.749
KGE50627.1	mltG	GW15_0219395	GW15_0204770	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.	0.575
KGE50627.1	mrdB	GW15_0219395	GW15_0203545	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.791
KGE50627.1	mtgA	GW15_0219395	GW15_0213765	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.	0.705
KGE50627.1	murG	GW15_0219395	GW15_0203305	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.	0.766
KGE50628.1	KGE50627.1	GW15_0219400	GW15_0219395	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.533
KGE50628.1	KGE50798.1	GW15_0219400	GW15_0218385	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dolichol-phosphate mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.515
KGE50628.1	KGE51103.1	GW15_0219400	GW15_0216505	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.873
KGE50628.1	KGE51160.1	GW15_0219400	GW15_0216385	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.612
KGE50628.1	KGE51229.1	GW15_0219400	GW15_0216100	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.673
KGE50628.1	KGE51421.1	GW15_0219400	GW15_0215000	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Alpha,alpha-trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.	0.526
KGE50628.1	KGE51947.1	GW15_0219400	GW15_0211340	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ceramide glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.673
KGE50628.1	KGE52390.1	GW15_0219400	GW15_0208855	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	O-antigen biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.697
KGE50628.1	KGE53089.1	GW15_0219400	GW15_0204555	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.432
KGE50628.1	KGE53090.1	GW15_0219400	GW15_0204560	Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.499