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| | Cagg_0239 | KEGG: cau:Caur_3371 magnesium chelatase, H subunit; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1269 aa) |
| | trpB | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (453 aa) |
| | Cagg_2135 | TIGRFAM: xanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: cau:Caur_1419 xanthine phosphoribosyltransferase. (204 aa) |
| | Cagg_2146 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (176 aa) |
| | dinG | DNA polymerase III, epsilon subunit; 3'-5' exonuclease. (934 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | cobS | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (251 aa) |
| | Cagg_2177 | PFAM: Phosphoglycerate mutase; KEGG: cau:Caur_1199 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (203 aa) |
| | purC | PFAM: SAICAR synthetase; KEGG: cau:Caur_1261 phosphoribosylaminoimidazolesuccinocarboxamide synthase. (250 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: cau:Caur_1262 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (341 aa) |
| | Cagg_2186 | KEGG: cau:Caur_1264 hypothetical protein. (228 aa) |
| | Cagg_2227 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_0925 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (203 aa) |
| | Cagg_2228 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: cau:Caur_0924 deaminase-reductase domain-containing protein. (289 aa) |
| | Cagg_2251 | PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: cau:Caur_2007 phosphoribosylglycinamide synthetase. (418 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (370 aa) |
| | Cagg_2296 | PFAM: beta-lactamase domain protein; KEGG: cau:Caur_1394 beta-lactamase-like protein. (302 aa) |
| | Cagg_2297 | KEGG: cau:Caur_1393 metal-dependent hydrolase. (280 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: cau:Caur_1390 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (273 aa) |
| | Cagg_2305 | PFAM: glycosyl transferase family 2; KEGG: rca:Rcas_0459 glycosyl transferase family protein. (722 aa) |
| | Cagg_2309 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | Cagg_2310 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | Cagg_2311 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | Cagg_2312 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | Cagg_2313 | RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor. (142 aa) |
| | Cagg_2314 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | Cagg_2315 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | Cagg_2316 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | Cagg_2317 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | Cagg_2319 | Magnesium chelatase; SMART: AAA ATPase; KEGG: cau:Caur_1255 magnesium chelatase. (350 aa) |
| | dacA | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (276 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (282 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (305 aa) |
| | Cagg_2392 | KEGG: cau:Caur_1020 hypothetical protein. (413 aa) |
| | Cagg_2414 | PFAM: cytochrome oxidase assembly; KEGG: cau:Caur_1010 cytochrome oxidase assembly. (321 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (186 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cau:Caur_1772 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1096 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (353 aa) |
| | Cagg_2499 | KEGG: cau:Caur_1016 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1260 aa) |
| | Cagg_2509 | TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: cau:Caur_1193 competence/damage-inducible protein CinA; Belongs to the CinA family. (395 aa) |
| | Cagg_2516 | PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: cau:Caur_1799 nucleotidyl transferase. (388 aa) |
| | coaA | TIGRFAM: pantothenate kinase; KEGG: cau:Caur_2043 pantothenate kinase. (318 aa) |
| | Cagg_2537 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (590 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa) |
| | Cagg_2589 | TIGRFAM: DNA polymerase III, delta prime subunit; SMART: AAA ATPase; KEGG: cau:Caur_1930 DNA polymerase III, delta prime subunit. (344 aa) |
| | Cagg_2614 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (345 aa) |
| | Cagg_2632 | TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; PFAM: UbiA prenyltransferase; KEGG: cau:Caur_2088 bacteriochlorophyll/chlorophyll a synthase. (310 aa) |
| | Cagg_2635 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (355 aa) |
| | Cagg_2639 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (409 aa) |
| | Cagg_2640 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: rrs:RoseRS_0969 riboflavin synthase subunit alpha. (203 aa) |
| | ribB | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (214 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (168 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: cau:Caur_0865 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (374 aa) |
| | Cagg_2663 | KEGG: cau:Caur_2039 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | purH | KEGG: cau:Caur_2058 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. (505 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1500 aa) |
| | rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1227 aa) |
| | Cagg_2716 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (314 aa) |
| | Cagg_2733 | PFAM: NMT1/THI5 like domain protein; KEGG: cau:Caur_0817 NMT1/THI5-like domain-containing protein. (349 aa) |
| | Cagg_2767 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (820 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (340 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (151 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (165 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (254 aa) |
| | Cagg_2915 | PFAM: aminotransferase class-III; KEGG: cau:Caur_2206 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa) |
| | pdxS | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (190 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (225 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa) |
| | Cagg_2958 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: cau:Caur_3520 adenylyl cyclase class-3/4/guanylyl cyclase. (421 aa) |
| | Cagg_2973 | TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: cau:Caur_2419 DNA polymerase III, delta subunit. (324 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) |
| | rpoA-2 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (318 aa) |
| | adk | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (222 aa) |
| | Cagg_3037 | PFAM: PfkB domain protein; KEGG: cau:Caur_2356 ribokinase-like domain-containing protein. (348 aa) |
| | Cagg_3055 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (272 aa) |
| | Cagg_3057 | KEGG: cau:Caur_2334 hypothetical protein. (259 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (377 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa) |
| | tdk | PFAM: thymidine kinase; KEGG: cau:Caur_2309 thymidine kinase. (193 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (207 aa) |
| | Cagg_3099 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cau:Caur_0436 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (438 aa) |
| | Cagg_3117 | PFAM: NMT1/THI5 like domain protein; KEGG: cau:Caur_0425 NMT1/THI5-like domain-containing protein. (331 aa) |
| | Cagg_3123 | Magnesium chelatase ATPase subunit I; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (370 aa) |
| | Cagg_3127 | KEGG: cau:Caur_0417 chlorophyllide reductase iron protein subunit X; TIGRFAM: chlorophyllide reductase iron protein subunit X; PFAM: NifH/frxC-family protein; Belongs to the NifH/BchL/ChlL family. (411 aa) |
| | Cagg_3129 | PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: cau:Caur_0415 2-vinyl bacteriochlorophyllide hydratase. (162 aa) |
| | Cagg_3135 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (282 aa) |
| | Cagg_3145 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_0399 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (224 aa) |
| | Cagg_3148 | Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (169 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (278 aa) |
| | thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (221 aa) |
| | Cagg_3167 | TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cau:Caur_0373 phosphomethylpyrimidine kinase. (263 aa) |
| | Cagg_3170 | PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cau:Caur_0536 hypothetical protein. (439 aa) |
| | Cagg_3177 | KEGG: cau:Caur_0504 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase. (346 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (613 aa) |
| | Cagg_3349 | PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: cau:Caur_1617 glutamine amidotransferase. (248 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (422 aa) |
| | pyrC-2 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (488 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: cau:Caur_1891 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa) |
| | Cagg_3367 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (475 aa) |
| | Cagg_3368 | KEGG: cau:Caur_0644 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa) |
| | Cagg_3375 | PFAM: Phosphoglycerate mutase; KEGG: cau:Caur_0633 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (213 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (205 aa) |
| | Cagg_0014 | KEGG: cau:Caur_2644 N-acetylglucosamine-1-phosphate uridyltransferase-like protein. (498 aa) |
| | folE | PFAM: GTP cyclohydrolase I; KEGG: cau:Caur_2641 GTP cyclohydrolase I. (224 aa) |
| | Cagg_0018 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cau:Caur_2640 putative 6-pyruvoyl tetrahydropterin synthase. (274 aa) |
| | Cagg_0019 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (378 aa) |
| | Cagg_0050 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_3899 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (206 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) |
| | Cagg_0061 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: cau:Caur_3282 phosphoribosylamine--glycine ligase. (433 aa) |
| | Cagg_0100 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (515 aa) |
| | Cagg_0158 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa) |
| | pyrC | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (330 aa) |
| | Cagg_0192 | KEGG: cau:Caur_2746 secreted hydrolase-like protein. (374 aa) |
| | Cagg_0193 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: cau:Caur_2745 cobalamin synthesis protein P47K. (320 aa) |
| | sigA | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (398 aa) |
| | Cagg_0204 | TIGRFAM: conserved hypothetical protein; SMART: von Willebrand factor type A; KEGG: cau:Caur_3409 hypothetical protein. (632 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (973 aa) |
| | Cagg_0224 | TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: cau:Caur_3462 ATP--cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (179 aa) |
| | Cagg_0246 | TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: cau:Caur_3394 acetoacetyl-CoA synthetase. (661 aa) |
| | Cagg_0282 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa) |
| | nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (150 aa) |
| | Cagg_0299 | KEGG: cau:Caur_3190 von Willebrand factor type A. (614 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (655 aa) |
| | Cagg_0321 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: rca:Rcas_2949 cobalamin synthesis protein P47K. (364 aa) |
| | Cagg_0332 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (211 aa) |
| | mtnP | Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (288 aa) |
| | Cagg_0385 | Glycine C-acetyltransferase; PFAM: aminotransferase class I and II; KEGG: tle:Tlet_2009 glycine C-acetyltransferase. (403 aa) |
| | Cagg_0395 | PFAM: transcriptional coactivator/pterin dehydratase; KEGG: cau:Caur_3165 transcriptional coactivator/pterin dehydratase. (94 aa) |
| | Cagg_0426 | TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: cau:Caur_3075 thiamine pyrophosphokinase. (213 aa) |
| | Cagg_0518 | PFAM: PUCC protein; major facilitator superfamily MFS_1; KEGG: rca:Rcas_1543 PucC protein. (449 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | Cagg_0575 | KEGG: cau:Caur_3151 magnesium chelatase; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1261 aa) |
| | Cagg_0581 | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (341 aa) |
| | Cagg_0608 | PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: cau:Caur_2796 cobalamin synthesis protein P47K. (408 aa) |
| | Cagg_0635 | PFAM: phosphoribulokinase/uridine kinase; KEGG: cau:Caur_2804 phosphoribulokinase/uridine kinase. (291 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (835 aa) |
| | Cagg_0725 | KEGG: cau:Caur_2678 hypothetical protein. (252 aa) |
| | Cagg_0766 | KEGG: cau:Caur_2922 hypothetical protein. (209 aa) |
| | Cagg_0778 | KEGG: cau:Caur_3604 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (332 aa) |
| | Cagg_0829 | PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cau:Caur_3790 hypothetical protein. (448 aa) |
| | Cagg_0847 | PFAM: aminotransferase class-III; KEGG: cau:Caur_3802 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa) |
| | Cagg_0850 | TIGRFAM: chlorophyllide reductase subunit Y; PFAM: oxidoreductase/nitrogenase component 1; KEGG: cau:Caur_3805 chlorophyllide reductase subunit Y. (438 aa) |
| | Cagg_0851 | TIGRFAM: chlorophyllide reductase subunit Z; PFAM: oxidoreductase/nitrogenase component 1; protein of unknown function DUF1197; KEGG: cau:Caur_3806 chlorophyllide reductase subunit Z. (493 aa) |
| | Cagg_0898 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_3743 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (202 aa) |
| | Cagg_0905 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (361 aa) |
| | Cagg_0950 | PFAM: thiamineS protein; KEGG: cau:Caur_3491 thiamineS protein. (94 aa) |
| | sigA-2 | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (381 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (471 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (522 aa) |
| | atpH | H+transporting two-sector ATPase delta (OSCP) subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (157 aa) |
| | atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (76 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (308 aa) |
| | Cagg_1023 | PFAM: ribonucleotide reductase; KEGG: cau:Caur_3331 ribonucleotide-diphosphate reductase subunit beta. (297 aa) |
| | Cagg_1061 | Hypothetical protein. (137 aa) |
| | Cagg_1063 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1499 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa) |
| | Cagg_1110 | KEGG: cau:Caur_2850 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (446 aa) |
| | Cagg_1116 | KEGG: cau:Caur_2844 tRNA-guanine transglycosylase; TIGRFAM: tRNA-guanine transglycosylase, various specificities; PFAM: Queuine/other tRNA-ribosyltransferase. (372 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (306 aa) |
| | Cagg_1133 | Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: cau:Caur_2832 carbamoyl-phosphate synthase L chain ATP-binding. (657 aa) |
| | Cagg_1163 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (409 aa) |
| | Cagg_1165 | TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: rca:Rcas_1862 MoaD family protein. (92 aa) |
| | Cagg_1192 | KEGG: cau:Caur_0117 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; SMART: AAA ATPase. (696 aa) |
| | Cagg_1230 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (127 aa) |
| | Cagg_1231 | PFAM: bifunctional deaminase-reductase domain protein; KEGG: cau:Caur_0157 5-amino-6-(5-phosphoribosylamino)uracil reductase. (222 aa) |
| | Cagg_1233 | KEGG: cau:Caur_0159 putative 6-pyruvoyl tetrahydropterin synthase. (130 aa) |
| | Cagg_1237 | KEGG: cau:Caur_0159 putative 6-pyruvoyl tetrahydropterin synthase. (130 aa) |
| | cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (491 aa) |
| | Cagg_1261 | PFAM: cobalbumin biosynthesis protein; KEGG: cau:Caur_2562 adenosylcobinamide-phosphate guanylyltransferase. (184 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (464 aa) |
| | Cagg_1263 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cau:Caur_2564 uroporphyrin-III C-methyltransferase. (260 aa) |
| | Cagg_1264 | TIGRFAM: precorrin-3B C17-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cau:Caur_2565 precorrin-3B C17-methyltransferase. (778 aa) |
| | purD | KEGG: cau:Caur_0629 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (414 aa) |
| | Cagg_1265 | KEGG: cau:Caur_2566 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. (267 aa) |
| | Cagg_1266 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cau:Caur_2567 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (240 aa) |
| | Cagg_1267 | KEGG: cau:Caur_2568 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Methyltransferase type 12. (401 aa) |
| | cbiD | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (411 aa) |
| | Cagg_1269 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cau:Caur_2570 precorrin-8X methylmutase CbiC/CobH. (219 aa) |
| | Cagg_1271 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: cau:Caur_2572 cobalamin (vitamin B12) biosynthesis CbiX protein. (465 aa) |
| | cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (313 aa) |
| | cbiN | Cobalt transport protein CbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (99 aa) |
| | cbiM | Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (246 aa) |
| | cobT | Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (353 aa) |
| | Cagg_1278 | KEGG: cau:Caur_2579 cobaltochelatase, CobN subunit; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase. (1406 aa) |
| | Cagg_1279 | KEGG: cau:Caur_2580 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (202 aa) |
| | acsF | Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (375 aa) |
| | Cagg_1286 | KEGG: cau:Caur_2591 magnesium chelatase; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1245 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (453 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (324 aa) |
| | Cagg_1290 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (254 aa) |
| | Cagg_1291 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cau:Caur_2596 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (352 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (356 aa) |
| | hemL | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cau:Caur_2598 glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (438 aa) |
| | hemF | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (302 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (206 aa) |
| | Cagg_1317 | PFAM: von Willebrand factor type A; KEGG: rca:Rcas_1710 von Willebrand factor type A. (1017 aa) |
| | fdhD | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (289 aa) |
| | Cagg_1338 | PFAM: aminotransferase class-III; KEGG: cau:Caur_2616 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (479 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (208 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (417 aa) |
| | rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (337 aa) |
| | udk | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: cau:Caur_1702 uridine kinase. (209 aa) |
| | Cagg_1398 | PFAM: molybdopterin binding domain; KEGG: cau:Caur_1790 molybdopterin binding domain-containing protein. (332 aa) |
| | Cagg_1409 | KEGG: cau:Caur_0782 hypothetical protein. (165 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (218 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | Cagg_1445 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: cau:Caur_2482 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (192 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (187 aa) |
| | Cagg_1486 | TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: cau:Caur_2177 cytidyltransferase-like protein. (170 aa) |
| | Cagg_1560 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (414 aa) |
| | Cagg_1582 | PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: cau:Caur_1876 metal-dependent phosphohydrolase. (192 aa) |
| | Cagg_1585 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: cau:Caur_1872 molybdopterin biosynthesis MoaE protein. (137 aa) |
| | Cagg_1586 | TIGRFAM: molybdopterin converting factor, subunit 1; MoaD family protein; PFAM: thiamineS protein; KEGG: cau:Caur_1871 molybdopterin converting factor, subunit 1. (82 aa) |
| | Cagg_1590 | Putative transmembrane anti-sigma factor; KEGG: cau:Caur_1867 hypothetical protein. (684 aa) |
| | nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa) |
| | Cagg_1599 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_1860 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa) |
| | Cagg_1663 | KEGG: cau:Caur_1437 hypothetical protein. (396 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (513 aa) |
| | cmk | KEGG: cau:Caur_0972 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (230 aa) |
| | Cagg_1673 | KEGG: cau:Caur_1166 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (465 aa) |
| | Cagg_1715 | dTDP-4-dehydrorhamnose reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cau:Caur_1114 dTDP-4-dehydrorhamnose reductase. (473 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (547 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (488 aa) |
| | Cagg_1772 | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (323 aa) |
| | Cagg_1773 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (556 aa) |
| | Cagg_1774 | KEGG: cau:Caur_0893 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (287 aa) |
| | Cagg_1840 | PFAM: Nucleotidyl transferase; KEGG: cau:Caur_1942 nucleotidyl transferase. (255 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa) |
| | Cagg_1874 | PFAM: ApaG domain protein; KEGG: cau:Caur_1552 ApaG. (139 aa) |
| | Cagg_1898 | AAA ATPase; KEGG: cau:Caur_1150 AAA ATPase. (354 aa) |
| | Cagg_1932 | KEGG: cau:Caur_1300 radical SAM domain-containing protein. (90 aa) |
| | Cagg_1941 | PFAM: NMT1/THI5 like domain protein; KEGG: hypothetical protein. (315 aa) |
| | Cagg_2003 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa) |
| | Cagg_2010 | PFAM: beta-lactamase domain protein; KEGG: cau:Caur_1386 beta-lactamase domain-containing protein. (257 aa) |
| | kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (422 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (503 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa) |
| | bchL | Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (273 aa) |
| | bchB | Light-independent protochlorophyllide reductase, B subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (544 aa) |
| | bchN | Light-independent protochlorophyllide reductase, N subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (425 aa) |
| | Cagg_3559 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (393 aa) |
| | Cagg_3574 | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (539 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (936 aa) |
| | Cagg_3608 | KEGG: cau:Caur_0310 hypothetical protein. (73 aa) |
| | rho-2 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (420 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (173 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (586 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (442 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cau:Caur_2708 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (232 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (403 aa) |
| | Cagg_3755 | PFAM: von Willebrand factor type A; protein of unknown function DUF1355; KEGG: cau:Caur_3110 von Willebrand factor type A. (958 aa) |
| | Cagg_3759 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_3114 RNA polymerase sigma-70 factor; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa) |
| | Cagg_3769 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: cau:Caur_2955 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (311 aa) |
| | adk-2 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (222 aa) |
| | Cagg_3789 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (644 aa) |
| | Cagg_3790 | AMP-dependent synthetase and ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa) |
| | Cagg_3822 | KEGG: rca:Rcas_4237 hypothetical protein. (370 aa) |
| | Cagg_3835 | PFAM: DRTGG domain protein; KEGG: cau:Caur_3921 DRTGG domain-containing protein. (356 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (356 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (246 aa) |
| | pyrE | Phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (216 aa) |
| | Cagg_3845 | RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: cau:Caur_3931 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) |
