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| atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa) | ||||
| Cagg_0100 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (515 aa) | ||||
| Cagg_0152 | PFAM: phospholipid/glycerol acyltransferase; KEGG: cau:Caur_0213 phospholipid/glycerol acyltransferase. (268 aa) | ||||
| Cagg_0158 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa) | ||||
| pyrC | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (330 aa) | ||||
| purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (973 aa) | ||||
| Cagg_0246 | TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: cau:Caur_3394 acetoacetyl-CoA synthetase. (661 aa) | ||||
| Cagg_0248 | PFAM: phospholipid/glycerol acyltransferase; KEGG: cau:Caur_3502 phospholipid/glycerol acyltransferase. (229 aa) | ||||
| Cagg_0282 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa) | ||||
| Cagg_0332 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (211 aa) | ||||
| Cagg_0426 | TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: cau:Caur_3075 thiamine pyrophosphokinase. (213 aa) | ||||
| pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) | ||||
| Cagg_0530 | PFAM: phosphatidate cytidylyltransferase; KEGG: cau:Caur_3570 phosphatidate cytidylyltransferase; Belongs to the CDS family. (279 aa) | ||||
| Cagg_0581 | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (341 aa) | ||||
| Cagg_0594 | PFAM: phospholipid/glycerol acyltransferase; KEGG: cau:Caur_0036 phospholipid/glycerol acyltransferase. (225 aa) | ||||
| Cagg_0635 | PFAM: phosphoribulokinase/uridine kinase; KEGG: cau:Caur_2804 phosphoribulokinase/uridine kinase. (291 aa) | ||||
| Cagg_0650 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cau:Caur_2813 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (200 aa) | ||||
| Cagg_0766 | KEGG: cau:Caur_2922 hypothetical protein. (209 aa) | ||||
| Cagg_0778 | KEGG: cau:Caur_3604 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (332 aa) | ||||
| tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) | ||||
| Cagg_0950 | PFAM: thiamineS protein; KEGG: cau:Caur_3491 thiamineS protein. (94 aa) | ||||
| atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) | ||||
| atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (471 aa) | ||||
| atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (522 aa) | ||||
| atpH | H+transporting two-sector ATPase delta (OSCP) subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (157 aa) | ||||
| atpF | ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) | ||||
| atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (76 aa) | ||||
| atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (308 aa) | ||||
| Cagg_1023 | PFAM: ribonucleotide reductase; KEGG: cau:Caur_3331 ribonucleotide-diphosphate reductase subunit beta. (297 aa) | ||||
| Cagg_1133 | Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: cau:Caur_2832 carbamoyl-phosphate synthase L chain ATP-binding. (657 aa) | ||||
| Cagg_1142 | TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; KEGG: cau:Caur_0235 hypothetical protein. (349 aa) | ||||
| Cagg_1163 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (409 aa) | ||||
| Cagg_1165 | TIGRFAM: MoaD family protein; PFAM: thiamineS protein; KEGG: rca:Rcas_1862 MoaD family protein. (92 aa) | ||||
| Cagg_1297 | PFAM: phospholipid/glycerol acyltransferase; KEGG: cau:Caur_0357 phospholipid/glycerol acyltransferase. (277 aa) | ||||
| fdhD | Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (289 aa) | ||||
| mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (208 aa) | ||||
| udk | TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: cau:Caur_1702 uridine kinase. (209 aa) | ||||
| Cagg_1398 | PFAM: molybdopterin binding domain; KEGG: cau:Caur_1790 molybdopterin binding domain-containing protein. (332 aa) | ||||
| Cagg_1409 | KEGG: cau:Caur_0782 hypothetical protein. (165 aa) | ||||
| Cagg_1414 | PFAM: phospholipase D/Transphosphatidylase; KEGG: cau:Caur_0790 phospholipase D/transphosphatidylase. (386 aa) | ||||
| coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (218 aa) | ||||
| Cagg_1448 | PFAM: diacylglycerol kinase catalytic region; KEGG: cau:Caur_2485 diacylglycerol kinase catalytic region. (325 aa) | ||||
| prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) | ||||
| Cagg_1560 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (414 aa) | ||||
| Cagg_1582 | PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: cau:Caur_1876 metal-dependent phosphohydrolase. (192 aa) | ||||
| Cagg_1585 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: cau:Caur_1872 molybdopterin biosynthesis MoaE protein. (137 aa) | ||||
| Cagg_1586 | TIGRFAM: molybdopterin converting factor, subunit 1; MoaD family protein; PFAM: thiamineS protein; KEGG: cau:Caur_1871 molybdopterin converting factor, subunit 1. (82 aa) | ||||
| nadK | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa) | ||||
| guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (513 aa) | ||||
| cmk | KEGG: cau:Caur_0972 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (230 aa) | ||||
| Cagg_1673 | KEGG: cau:Caur_1166 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (465 aa) | ||||
| pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (547 aa) | ||||
| purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (488 aa) | ||||
| Cagg_1772 | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (323 aa) | ||||
| Cagg_1773 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (556 aa) | ||||
| Cagg_1774 | KEGG: cau:Caur_0893 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (287 aa) | ||||
| Cagg_1794 | PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein; KEGG: cau:Caur_1572 myo-inositol-1-phosphate synthase. (361 aa) | ||||
| purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) | ||||
| gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (209 aa) | ||||
| Cagg_1898 | AAA ATPase; KEGG: cau:Caur_1150 AAA ATPase. (354 aa) | ||||
| fabZ | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (144 aa) | ||||
| kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (422 aa) | ||||
| Cagg_2135 | TIGRFAM: xanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: cau:Caur_1419 xanthine phosphoribosyltransferase. (204 aa) | ||||
| Cagg_2141 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cau:Caur_1425 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (212 aa) | ||||
| upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) | ||||
| purC | PFAM: SAICAR synthetase; KEGG: cau:Caur_1261 phosphoribosylaminoimidazolesuccinocarboxamide synthase. (250 aa) | ||||
| purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: cau:Caur_1262 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (341 aa) | ||||
| Cagg_2229 | PFAM: phosphatidylserine decarboxylase-related; KEGG: cau:Caur_0923 phosphatidylserine decarboxylase-related. (243 aa) | ||||
| Cagg_2251 | PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: cau:Caur_2007 phosphoribosylglycinamide synthetase. (418 aa) | ||||
| dacA | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (276 aa) | ||||
| Cagg_2358 | PFAM: phospholipid/glycerol acyltransferase; KEGG: cau:Caur_1222 phospholipid/glycerol acyltransferase. (430 aa) | ||||
| accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (282 aa) | ||||
| accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (305 aa) | ||||
| Cagg_2392 | KEGG: cau:Caur_1020 hypothetical protein. (413 aa) | ||||
| dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (186 aa) | ||||
| carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cau:Caur_1772 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1096 aa) | ||||
| moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (353 aa) | ||||
| Cagg_2506 | PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cau:Caur_1190 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (188 aa) | ||||
| Cagg_2509 | TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: cau:Caur_1193 competence/damage-inducible protein CinA; Belongs to the CinA family. (395 aa) | ||||
| coaA | TIGRFAM: pantothenate kinase; KEGG: cau:Caur_2043 pantothenate kinase. (318 aa) | ||||
| Cagg_2537 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (590 aa) | ||||
| Cagg_2609 | PFAM: metallophosphoesterase; KEGG: cau:Caur_2032 metallophosphoesterase. (310 aa) | ||||
| Cagg_2635 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (355 aa) | ||||
| carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: cau:Caur_0865 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (374 aa) | ||||
| Cagg_2663 | KEGG: cau:Caur_2039 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) | ||||
| purH | KEGG: cau:Caur_2058 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. (505 aa) | ||||
| ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (151 aa) | ||||
| moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (165 aa) | ||||
| purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (254 aa) | ||||
| pdxS | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa) | ||||
| pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (190 aa) | ||||
| tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (225 aa) | ||||
| Cagg_2958 | PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: cau:Caur_3520 adenylyl cyclase class-3/4/guanylyl cyclase. (421 aa) | ||||
| coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa) | ||||
| adk | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (222 aa) | ||||
| Cagg_3055 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (272 aa) | ||||
| Cagg_3057 | KEGG: cau:Caur_2334 hypothetical protein. (259 aa) | ||||
| purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (377 aa) | ||||
| purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa) | ||||
| tdk | PFAM: thymidine kinase; KEGG: cau:Caur_2309 thymidine kinase. (193 aa) | ||||
| nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (207 aa) | ||||
| Cagg_3148 | Molybdenum cofactor synthesis domain protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (169 aa) | ||||
| thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (278 aa) | ||||
| thiE | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (221 aa) | ||||
| pyrC-2 | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (488 aa) | ||||
| pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: cau:Caur_1891 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa) | ||||
| Cagg_3376 | PFAM: diacylglycerol kinase; KEGG: cau:Caur_0632 diacylglycerol kinase. (134 aa) | ||||
| purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (205 aa) | ||||
| purD | KEGG: cau:Caur_0629 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (414 aa) | ||||
| Cagg_3390 | KEGG: cau:Caur_0617 GHMP kinase domain-containing protein. (389 aa) | ||||
| guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa) | ||||
| Cagg_3574 | Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (539 aa) | ||||
| gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (193 aa) | ||||
| apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (173 aa) | ||||
| Cagg_3700 | PFAM: diacylglycerol kinase catalytic region; KEGG: cau:Caur_2704 diacylglycerol kinase catalytic region. (304 aa) | ||||
| Cagg_3703 | KEGG: cau:Caur_2707 metallophosphoesterase. (490 aa) | ||||
| Cagg_3769 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: cau:Caur_2955 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (311 aa) | ||||
| adk-2 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (222 aa) | ||||
| Cagg_3789 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (644 aa) | ||||
| Cagg_3790 | AMP-dependent synthetase and ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (633 aa) | ||||
| Cagg_3835 | PFAM: DRTGG domain protein; KEGG: cau:Caur_3921 DRTGG domain-containing protein. (356 aa) | ||||
| pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (356 aa) | ||||
| pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (246 aa) | ||||
| pyrE | Phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (216 aa) | ||||
| Cagg_0014 | KEGG: cau:Caur_2644 N-acetylglucosamine-1-phosphate uridyltransferase-like protein. (498 aa) | ||||
| folE | PFAM: GTP cyclohydrolase I; KEGG: cau:Caur_2641 GTP cyclohydrolase I. (224 aa) | ||||
| Cagg_0038 | PFAM: transferase hexapeptide repeat containing protein; KEGG: cau:Caur_3908 hexapaptide repeat-containing transferase. (196 aa) | ||||
| folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa) | ||||
| Cagg_0061 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: cau:Caur_3282 phosphoribosylamine--glycine ligase. (433 aa) | ||||