(95 nodes) DNA replication network (Fusarium oxysporum f. sp. radiciscucumerinum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AU210_000729	AAA domain-containing protein. (382 aa)
	AU210_016775	Uncharacterized protein. (231 aa)
	AU210_016182	Uncharacterized protein. (265 aa)
	AU210_016776	Uncharacterized protein. (146 aa)
	AU210_016487	RNase H domain-containing protein. (288 aa)
	AU210_016496	RNase H domain-containing protein. (223 aa)
	AU210_015544	Uncharacterized protein. (369 aa)
	AU210_015548	RNase H domain-containing protein. (224 aa)
	AU210_015574	Uncharacterized protein. (180 aa)
	AU210_015798	Gag_pre-integrs domain-containing protein. (942 aa)
	AU210_015901	Uncharacterized protein. (401 aa)
	AU210_015981	Gag_pre-integrs domain-containing protein. (1223 aa)
	AU210_015896	Uncharacterized protein. (462 aa)
	AU210_016086	Integrase catalytic domain-containing protein. (1013 aa)
	AU210_016105	Gag_pre-integrs domain-containing protein. (939 aa)
	AU210_015840	Gag_pre-integrs domain-containing protein. (942 aa)
	AU210_010106	Uncharacterized protein. (336 aa)
	AU210_014070	Uncharacterized protein. (1293 aa)
	AU210_016139	RNase H domain-containing protein. (221 aa)
	AU210_014630	Integrase catalytic domain-containing protein. (303 aa)
	AU210_012371	Uncharacterized protein. (401 aa)
	AU210_016765	RNase H domain-containing protein. (142 aa)
	AU210_014222	RNase H domain-containing protein. (144 aa)
	AU210_012460	MCM_lid domain-containing protein. (240 aa)
	AU210_012454	Gag_pre-integrs domain-containing protein. (997 aa)
	AU210_012330	Gag_pre-integrs domain-containing protein. (800 aa)
	AU210_012502	Uncharacterized protein. (144 aa)
	AU210_015952	Uncharacterized protein. (265 aa)
	AU210_015542	Uncharacterized protein. (94 aa)
	AU210_013168	Uncharacterized protein. (159 aa)
	AU210_016268	Integrase catalytic domain-containing protein. (969 aa)
	AU210_011295	Uncharacterized protein. (597 aa)
	AU210_011362	Amino_oxidase domain-containing protein. (507 aa)
	AU210_011636	Uncharacterized protein. (447 aa)
	AU210_011495	Uncharacterized protein. (553 aa)
	AU210_011641	Uncharacterized protein. (156 aa)
	AU210_010216	Uncharacterized protein. (381 aa)
	AU210_010628	Uncharacterized protein. (310 aa)
	AU210_010594	DNA ligase. (869 aa)
	AU210_011069	Uncharacterized protein. (413 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (353 aa)
	AU210_009667	DNA polymerase. (1694 aa)
	AU210_010626	Uncharacterized protein. (1402 aa)
	AU210_011498	Uncharacterized protein. (794 aa)
	AU210_011724	Macro domain-containing protein. (222 aa)
	AU210_011581	Uncharacterized protein. (342 aa)
	AU210_007508	Uncharacterized protein. (190 aa)
	AU210_010051	Uncharacterized protein. (147 aa)
	AU210_008413	DNA helicase; Belongs to the MCM family. (858 aa)
	AU210_005527	Uncharacterized protein. (169 aa)
	AU210_006603	Uncharacterized protein. (138 aa)
	AU210_006048	AAA domain-containing protein. (354 aa)
	AU210_006088	Uncharacterized protein. (503 aa)
	AU210_009461	Zn(2)-C6 fungal-type domain-containing protein. (749 aa)
	AU210_006506	DNA helicase; Belongs to the MCM family. (721 aa)
	AU210_008044	DNA_pol_E_B domain-containing protein. (775 aa)
	AU210_008266	DNA helicase; Belongs to the MCM family. (957 aa)
	AU210_007777	Uncharacterized protein. (521 aa)
	AU210_006244	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (655 aa)
	AU210_007813	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	AU210_008146	AAA domain-containing protein. (1157 aa)
	AU210_004050	Uncharacterized protein. (203 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
	AU210_004045	AAA domain-containing protein. (392 aa)
	AU210_004084	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2211 aa)
	AU210_004533	Uncharacterized protein. (215 aa)
	AU210_004374	DNA ligase. (856 aa)
	AU210_005961	Uncharacterized protein. (265 aa)
	AU210_006077	DNA polymerase. (1104 aa)
	AU210_005097	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
	AU210_002708	Uncharacterized protein. (1582 aa)
	AU210_002718	Uncharacterized protein. (417 aa)
	AU210_006662	Uncharacterized protein. (148 aa)
	AU210_002874	CBFD_NFYB_HMF domain-containing protein. (177 aa)
	AU210_004479	Uncharacterized protein. (270 aa)
	AU210_003012	Exo84_C domain-containing protein. (674 aa)
	AU210_004006	Uncharacterized protein. (212 aa)
	AU210_004015	Amino_oxidase domain-containing protein. (519 aa)
	AU210_003108	Uncharacterized protein. (277 aa)
	AU210_004397	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (499 aa)
	AU210_003275	Uncharacterized protein. (1201 aa)
	AU210_000755	CBFD_NFYB_HMF domain-containing protein. (230 aa)
	AU210_002525	Zds_C domain-containing protein. (856 aa)
	AU210_004657	RNase H domain-containing protein. (145 aa)
	AU210_001279	AAA domain-containing protein. (352 aa)
	AU210_002256	Gag_pre-integrs domain-containing protein. (1462 aa)
	AU210_005011	DNA helicase; Belongs to the MCM family. (879 aa)
	AU210_001562	Uncharacterized protein. (512 aa)
	AU210_000474	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (343 aa)
	AU210_001330	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (339 aa)
	AU210_000887	Vezatin domain-containing protein. (617 aa)
	AU210_001281	Replication factor C subunit 1. (1047 aa)
	AU210_001439	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (167 aa)
	AU210_000886	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	AU210_001094	DNA helicase; Belongs to the MCM family. (1015 aa)

Your Current Organism:

Fusarium oxysporum f. sp. radiciscucumerinum

NCBI taxonomy Id: 327505
Other names: F. oxysporum f. sp. radicis-cucumerinum, Fusarium oxysporum f. sp. radicis-cucumerinum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AU210_000474	AU210_000886	A0A2H3HXT1	A0A2H3I951	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.571
AU210_000474	AU210_000887	A0A2H3HXT1	A0A2H3I4X5	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Vezatin domain-containing protein.	0.571
AU210_000474	AU210_001279	A0A2H3HXT1	A0A2H3HUM6	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	AAA domain-containing protein.	0.468
AU210_000474	AU210_001330	A0A2H3HXT1	A0A2H3I3A9	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.729
AU210_000474	AU210_004084	A0A2H3HXT1	A0A2H3HG94	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.432
AU210_000474	AU210_006603	A0A2H3HXT1	A0A2H3H5T9	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Uncharacterized protein.	0.635
AU210_000474	AU210_011498	A0A2H3HXT1	A0A2H3GTB3	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Uncharacterized protein.	0.435
AU210_000474	AU210_016487	A0A2H3HXT1	A0A2H3FPM5	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	RNase H domain-containing protein.	0.752
AU210_000474	FEN1	A0A2H3HXT1	A0A2H3GN34	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.525
AU210_000729	AU210_000755	A0A2H3I693	A0A2H3HSQ2	AAA domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.796
AU210_000729	AU210_000886	A0A2H3I693	A0A2H3I951	AAA domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
AU210_000729	AU210_000887	A0A2H3I693	A0A2H3I4X5	AAA domain-containing protein.	Vezatin domain-containing protein.	0.995
AU210_000729	AU210_001094	A0A2H3I693	A0A2H3I9X6	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.905
AU210_000729	AU210_001279	A0A2H3I693	A0A2H3HUM6	AAA domain-containing protein.	AAA domain-containing protein.	0.999
AU210_000729	AU210_001281	A0A2H3I693	A0A2H3I6C3	AAA domain-containing protein.	Replication factor C subunit 1.	0.999
AU210_000729	AU210_001330	A0A2H3I693	A0A2H3I3A9	AAA domain-containing protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.733
AU210_000729	AU210_002708	A0A2H3I693	A0A2H3HLU6	AAA domain-containing protein.	Uncharacterized protein.	0.813
AU210_000729	AU210_002718	A0A2H3I693	A0A2H3HLV7	AAA domain-containing protein.	Uncharacterized protein.	0.524
AU210_000729	AU210_003108	A0A2H3I693	A0A2H3HPT9	AAA domain-containing protein.	Uncharacterized protein.	0.916
AU210_000729	AU210_004045	A0A2H3I693	A0A2H3HG49	AAA domain-containing protein.	AAA domain-containing protein.	0.999