STRINGSTRING
dinG dinG mutS2 mutS2 OJG11197.1 OJG11197.1 OJG10943.1 OJG10943.1 OJG10949.1 OJG10949.1 OJG10590.1 OJG10590.1 xseA xseA OJG10307.1 OJG10307.1 polC polC addA addA OJG12309.1 OJG12309.1 lexA lexA mutL mutL mutS mutS prsA prsA OJG09468.1 OJG09468.1 OJG09257.1 OJG09257.1 OJG09204.1 OJG09204.1 ligA ligA OJG09070.1 OJG09070.1 OJG11385.1 OJG11385.1 dnaX dnaX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dinGHypothetical protein; 3'-5' exonuclease. (942 aa)
mutS2MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (791 aa)
OJG11197.1DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (637 aa)
OJG10943.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (376 aa)
OJG10949.1Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (168 aa)
OJG10590.1Hypothetical protein. (342 aa)
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (446 aa)
OJG10307.1DNA polymerase III, delta subunit. (310 aa)
polCDNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1458 aa)
addAHelicase-exonuclease AddAB, AddA subunit; ATP-dependent DNA helicase. (1208 aa)
OJG12309.1single-stranded-DNA-specific exonuclease RecJ. (768 aa)
lexALexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (205 aa)
mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (650 aa)
mutSDNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (847 aa)
prsAHypothetical protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (342 aa)
OJG09468.1DNA polymerase III, delta subunit. (344 aa)
OJG09257.1DNA polymerase III alpha subunit. (1108 aa)
OJG09204.1DNA helicase IV. (760 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (672 aa)
OJG09070.1ATP-dependent DNA helicase PcrA. (742 aa)
OJG11385.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (202 aa)
dnaXDNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (585 aa)
Your Current Organism:
Enterococcus aquimarinus
NCBI taxonomy Id: 328396
Other names: API 8407116, CCM 7283, CCUG 51308, DSM 17690, E. aquimarinus, Enterococcus aquamarinus, Enterococcus aquimarinus Svec et al. 2005, LMG 16607, LMG:16607
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