node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AM1_0995 | guaA | AM1_0995 | AM1_4428 | Glutamine amidotransferase, class I, putative. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.929 |
AM1_2492 | guaA | AM1_2492 | AM1_4428 | LD-carboxypeptidase family protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.443 |
carA | guaA | AM1_5193 | AM1_4428 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.593 |
carA | purQ | AM1_5193 | AM1_1434 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.945 |
carA | pyrG | AM1_5193 | AM1_2914 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.418 |
cobB | cobQ | AM1_2881 | AM1_4245 | Cobyrinic Acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.987 |
cobQ | cobB | AM1_4245 | AM1_2881 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cobyrinic Acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.987 |
cobQ | guaA | AM1_4245 | AM1_4428 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.430 |
guaA | AM1_0995 | AM1_4428 | AM1_0995 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamine amidotransferase, class I, putative. | 0.929 |
guaA | AM1_2492 | AM1_4428 | AM1_2492 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | LD-carboxypeptidase family protein. | 0.443 |
guaA | carA | AM1_4428 | AM1_5193 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.593 |
guaA | cobQ | AM1_4428 | AM1_4245 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.430 |
guaA | hisH | AM1_4428 | AM1_2049 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.465 |
guaA | pabA | AM1_4428 | AM1_1430 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Anthranilate synthase component II. | 0.404 |
guaA | purQ | AM1_4428 | AM1_1434 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.666 |
guaA | pyrG | AM1_4428 | AM1_2914 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.989 |
hisH | guaA | AM1_2049 | AM1_4428 | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.465 |
hisH | pabA | AM1_2049 | AM1_1430 | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Anthranilate synthase component II. | 0.429 |
pabA | guaA | AM1_1430 | AM1_4428 | Anthranilate synthase component II. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.404 |
pabA | hisH | AM1_1430 | AM1_2049 | Anthranilate synthase component II. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.429 |