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| | NIDE2591 | Amine oxidase, flavin-containing; Function of strongly homologous gene; enzyme. (420 aa) |
| | pssA-2 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Function of strongly homologous gene; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (208 aa) |
| | fabF3 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (418 aa) |
| | acpP-2 | Putative Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (113 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (360 aa) |
| | NIDE2688 | Homologs of previously reported genes of unknown function. (371 aa) |
| | NIDE2691 | Putative D-alanine-poly(phosphoribitol) ligase, subunit 2 (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (90 aa) |
| | NIDE2711 | Putative Tyrosine-protein kinase Etk; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (731 aa) |
| | NIDE2776 | Putative NAD-dependent alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (343 aa) |
| | NIDE2866 | Homologs of previously reported genes of unknown function; 1644165, 8090199. (359 aa) |
| | NIDE2896 | Putative Lipopolysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (784 aa) |
| | glmU | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (539 aa) |
| | NIDE2953 | Protein of unknown function, Phospholipase D-like; No homology to any previously reported sequences; 8732763, 8755242. (752 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (247 aa) |
| | kdsC | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (153 aa) |
| | NIDE3023 | Putative Lipopolysaccharide heptosyltransferase III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (347 aa) |
| | NIDE3030 | Putative Lipopolysaccharide heptosyltransferase II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (347 aa) |
| | rfaF/gmhB | Heptosyltransferase II; Function of strongly homologous gene; enzyme. (563 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (360 aa) |
| | waaA | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (452 aa) |
| | lpxB | Lipid-A-disaccharide synthetase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (377 aa) |
| | NIDE3039 | Conserved protein of unknown function, DUF1009; Homologs of previously reported genes of unknown function. (280 aa) |
| | lpxA | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (269 aa) |
| | fabZ | (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | paaF | Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (262 aa) |
| | NIDE3103 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (407 aa) |
| | fadA | 3-ketoacyl-CoA thiolase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa) |
| | atoB | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | paaH | 3-hydroxybutyryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme. (294 aa) |
| | NIDE3122 | Putative Enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (282 aa) |
| | prpD | 2-methylcitrate dehydratase; Function of strongly homologous gene; enzyme. (467 aa) |
| | NIDE3274 | Protein of unknown function, contains TPR repeats; No homology to any previously reported sequences; 16893176, 7667876, 9482716. (270 aa) |
| | NIDE3291 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (344 aa) |
| | NIDE3331 | Putative Acyl carrier protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (78 aa) |
| | NIDE3385 | Polyprenyl-diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family. (334 aa) |
| | NIDE3810 | Conserved protein of unknown function, contains Ankyrin repeats; Homologs of previously reported genes of unknown function; 8108379. (374 aa) |
| | NIDE3855 | Putative Acyl carrier protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (85 aa) |
| | NIDE3913 | Putative Glycosyl transferase, family 39; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (569 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (309 aa) |
| | NIDE4081 | Homologs of previously reported genes of unknown function. (127 aa) |
| | NIDE4082 | Putative Glycosyl transferase, family 39; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (599 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa) |
| | NIDE0525 | Putative Metallophosphoesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (277 aa) |
| | NIDE0517 | Homologs of previously reported genes of unknown function. (378 aa) |
| | NIDE0425 | Putative Acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (231 aa) |
| | lpxC | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (308 aa) |
| | accA | Acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (322 aa) |
| | plsY | Conserved membrane protein, putative glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (200 aa) |
| | pgsA-2 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (204 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. (273 aa) |
| | kdsB | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (263 aa) |
| | accC | Acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | accB | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (191 aa) |
| | NIDE2408 | Putative Lipopolysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (589 aa) |
| | NIDE2397 | Putative ADP-heptose-LPS heptosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (373 aa) |
| | NIDE2337 | Putative Glycosyl transferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (558 aa) |
| | NIDE2335 | Putative Glycosyltransferase, family 9; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (398 aa) |
| | NIDE2152 | Putative Polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1517 aa) |
| | NIDE2002 | Homologs of previously reported genes of unknown function. (411 aa) |
| | NIDE1998 | Conserved protein of unknown function (N-terminal fragment); Homologs of previously reported genes of unknown function. (60 aa) |
| | NIDE1991 | Homologs of previously reported genes of unknown function. (345 aa) |
| | NIDE1989 | Homologs of previously reported genes of unknown function. (424 aa) |
| | NIDE1825 | Conserved exported protein of unknown function, putative Endonuclease; Homologs of previously reported genes of unknown function. (181 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase (NADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (259 aa) |
| | accD | Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (278 aa) |
| | crtB | Phytoene synthase; Function of strongly homologous gene; enzyme. (303 aa) |
| | NIDE1519 | Putative Pytoene desaturase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (436 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDS family. (282 aa) |
| | dxr | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa) |
| | htrB | Lipid A biosynthesis lauroyl acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (312 aa) |
| | NIDE1238 | Squalene synthase; Function of strongly homologous gene; enzyme. (319 aa) |
| | NIDE1096 | Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function; 14659697, 1882418, 7667876, 9482716. (466 aa) |
| | pssA | CDP-diacylglycerol-serine O-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (261 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (216 aa) |
| | NIDE0965 | Putative Hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (344 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (401 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (648 aa) |
| | shc | Squalene-hopene cyclase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (724 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (320 aa) |
| | fabH-2 | 3-ketoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (330 aa) |
| | fabF2 | 3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (416 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | fabD | Malonyl-CoA-(acyl-carrier-protein) transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (316 aa) |
| | fabH | 3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (343 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (304 aa) |
| | pgsA | CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (178 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (373 aa) |
| | NIDE0744 | Conserved membrane protein of unknown function, putative glycosyltransferase; Homologs of previously reported genes of unknown function. (550 aa) |
| | NIDE0736 | Putative sugar nucleotidyltransferase and phosphatidyltransferase (bifunctional enzyme); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (483 aa) |
| | ispA | Geranyltranstransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family. (326 aa) |
| | NIDE0631 | Exported protein of unknown function; No homology to any previously reported sequences. (345 aa) |
| | fabF | Beta-ketoacyl ACP synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (441 aa) |
| | NIDE0541 | Putative 2-oxoglutarate-Fe(II) oxygenase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (253 aa) |
