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NIDE1925 NIDE1925 ileS ileS NIDE0562 NIDE0562 panC panC argG argG ydaO ydaO cysD cysD cysH cysH trmU trmU phr phr nadD nadD thiI thiI NIDE1168 NIDE1168 queC queC nadE nadE guaA guaA valS valS NIDE1838 NIDE1838 NIDE1844 NIDE1844 NIDE1922 NIDE1922 NIDE1927 NIDE1927 coaD coaD asnB asnB tyrS tyrS tilS tilS ribF ribF asnB-2 asnB-2 metG metG NIDE2995 NIDE2995 asnB4 asnB4 argS argS trpS trpS NIDE3396 NIDE3396 NIDE3731 NIDE3731 NIDE3757 NIDE3757 NIDE3785 NIDE3785 NIDE3838 NIDE3838 NIDE3863 NIDE3863 NIDE3897 NIDE3897 glnS glnS gltX gltX NIDE4067 NIDE4067 cysS cysS leuS leuS rfaEb rfaEb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NIDE1925Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (172 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (939 aa)
NIDE0562Putative Universal stress protein UspA (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (703 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (285 aa)
argGArgininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
ydaOPutative PP-loop ATPase, YdaO-related; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. Belongs to the TtcA family. (287 aa)
cysDSulfate adenylyltransferase, subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (265 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (240 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (360 aa)
phrDeoxyribodipyrimidine photolyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DNA photolyase family. (481 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (226 aa)
thiIPutative Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (392 aa)
NIDE1168Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (284 aa)
queCQueuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (232 aa)
nadENAD(+) synthase (glutamine-hydrolyzing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (589 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (518 aa)
valSValyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (920 aa)
NIDE1838Conserved protein of unknown function, putative Universal stress protein; Homologs of previously reported genes of unknown function; 8152377, 9405142. (285 aa)
NIDE1844Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (185 aa)
NIDE1922Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (287 aa)
NIDE1927Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (311 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
asnBAsparagine synthetase, glutamine-hydrolyzing; Function of strongly homologous gene; enzyme. (668 aa)
tyrSTyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (405 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (461 aa)
ribFRiboflavin biosynthesis protein RibF; Function of strongly homologous gene; enzyme; Belongs to the ribF family. (321 aa)
asnB-2Asparagine synthase (glutamine-hydrolyzing); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (631 aa)
metGMethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. (663 aa)
NIDE2995Putative Asparagine synthetase (glutamine-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (645 aa)
asnB4Asparagine synthase (glutamine-hydrolyzing); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (610 aa)
argSArginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (584 aa)
trpSTryptophanyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (329 aa)
NIDE3396Putative PP-loop ATPase, YdaO type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TtcA family. (305 aa)
NIDE3731Conserved protein of unknown function, PP-loop superfamily; Homologs of previously reported genes of unknown function; 7731953. (273 aa)
NIDE3757Putative Universal stress protein UspA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (284 aa)
NIDE3785Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (326 aa)
NIDE3838Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (294 aa)
NIDE3863Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (285 aa)
NIDE3897Putative Universal stress protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (325 aa)
glnSGlutaminyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (567 aa)
gltXGlutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (471 aa)
NIDE4067Homologs of previously reported genes of unknown function. (270 aa)
cysSCysteinyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (486 aa)
leuSLeucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (811 aa)
rfaEbD-beta-D-heptose 1-phosphate adenosyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (160 aa)
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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