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cheA cheA NIDE4272 NIDE4272 NIDE4240 NIDE4240 NIDE3983 NIDE3983 NIDE3963 NIDE3963 NIDE3941 NIDE3941 NIDE3753 NIDE3753 NIDE3607 NIDE3607 NIDE3593 NIDE3593 NIDE3587 NIDE3587 NIDE3586 NIDE3586 NIDE3570 NIDE3570 NIDE3521 NIDE3521 NIDE3462 NIDE3462 NIDE3415 NIDE3415 mutL mutL NIDE3284 NIDE3284 NIDE3246 NIDE3246 NIDE3244 NIDE3244 NIDE3162 NIDE3162 NIDE3092 NIDE3092 NIDE3052 NIDE3052 NIDE3050 NIDE3050 NIDE2654 NIDE2654 NIDE2629 NIDE2629 NIDE2372 NIDE2372 cheA-2 cheA-2 NIDE2323 NIDE2323 NIDE2283 NIDE2283 NIDE2265 NIDE2265 NIDE2119 NIDE2119 top6B top6B NIDE2021 NIDE2021 NIDE1908 NIDE1908 NIDE1772 NIDE1772 NIDE1587 NIDE1587 NIDE1586 NIDE1586 NIDE1563 NIDE1563 NIDE1493 NIDE1493 NIDE1491 NIDE1491 NIDE1255 NIDE1255 NIDE1227 NIDE1227 NIDE1222 NIDE1222 NIDE1163 NIDE1163 NIDE1119 NIDE1119 NIDE1109 NIDE1109 NIDE1046 NIDE1046 NIDE0964 NIDE0964 NIDE0936 NIDE0936 NIDE0857 NIDE0857 NIDE0816 NIDE0816 NIDE0815 NIDE0815 NIDE0807 NIDE0807 NIDE0805 NIDE0805 NIDE0804 NIDE0804 NIDE0778 NIDE0778 NIDE0694 NIDE0694 NIDE0686 NIDE0686 NIDE0585 NIDE0585 NIDE0584 NIDE0584 NIDE0578 NIDE0578 NIDE0557 NIDE0557 NIDE0543 NIDE0543 NIDE0542 NIDE0542 cztS cztS NIDE0241 NIDE0241 NIDE0224 NIDE0224 NIDE0222 NIDE0222 NIDE0166 NIDE0166 gyrB gyrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cheAChemotaxis protein histidine kinase CheA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (630 aa)
NIDE4272Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (465 aa)
NIDE4240Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1314 aa)
NIDE3983Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (389 aa)
NIDE3963Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (620 aa)
NIDE3941Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (892 aa)
NIDE3753Hybrid sensor histidine kinase; Function of strongly homologous gene; enzyme. (504 aa)
NIDE3607Response regulator with ATPase domain; Function of strongly homologous gene; regulator. (307 aa)
NIDE3593Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (786 aa)
NIDE3587Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (830 aa)
NIDE3586Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (349 aa)
NIDE3570Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1033 aa)
NIDE3521Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (677 aa)
NIDE3462Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (924 aa)
NIDE3415Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (590 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (599 aa)
NIDE3284Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1058 aa)
NIDE3246Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (380 aa)
NIDE3244Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (651 aa)
NIDE3162Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (528 aa)
NIDE3092Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1051 aa)
NIDE3052Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (809 aa)
NIDE3050Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (915 aa)
NIDE2654Chemosensory pili system protein ChpA (sensor histidine kinase/response regulator); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1129 aa)
NIDE2629Putative Histidine kinase, contains GAF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (687 aa)
NIDE2372Putative Response regulator with ATPase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (299 aa)
cheA-2Chemotaxis protein histidine kinase CheA; Function of homologous gene experimentally demonstrated in an other organism; regulator. (715 aa)
NIDE2323Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (950 aa)
NIDE2283Putative Sensor histidine kinase FleS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (429 aa)
NIDE2265Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (490 aa)
NIDE2119Putative Histidine kinase with protein phosphatase region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (563 aa)
top6BDNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (662 aa)
NIDE2021Putative Histidine kinase, contains GAF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (438 aa)
NIDE1908Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1013 aa)
NIDE1772Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (657 aa)
NIDE1587Protein of unknown function, putative Sensory histidine kinase with methyltransferase region; No homology to any previously reported sequences; 11369279, 11489844, 15009198, 16176121, 16622408, 18076326, 7699720, 9301332, 9382818. (1396 aa)
NIDE1586Putative Histidine kinase, contains GAF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (426 aa)
NIDE1563Putative Sensor histidine kinase CusS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (481 aa)
NIDE1493Putative Sensor histidine kinase with MCP region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (590 aa)
NIDE1491Putative Hybrid sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (998 aa)
NIDE1255Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (383 aa)
NIDE1227Histidine kinase; Function of strongly homologous gene; enzyme. (589 aa)
NIDE1222Sensor histidine kinase; Function of strongly homologous gene; enzyme. (765 aa)
NIDE1163Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (351 aa)
NIDE1119Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (645 aa)
NIDE1109Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (768 aa)
NIDE1046Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1340 aa)
NIDE0964Putative Histidine kinase, contains GAF domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1002 aa)
NIDE0936Putative Sonsor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (470 aa)
NIDE0857Putative Phosphate regulon sensor histidine kinase PhoR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (619 aa)
NIDE0816Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (945 aa)
NIDE0815Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1431 aa)
NIDE0807Putative Histidine kinase, containing PAS domain S-box; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (578 aa)
NIDE0805Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1210 aa)
NIDE0804Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (415 aa)
NIDE0778Putative Sensor protein PilS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (619 aa)
NIDE0694Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences. (610 aa)
NIDE0686Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences. (922 aa)
NIDE0585Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1610 aa)
NIDE0584Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (954 aa)
NIDE0578Protein of unknown function, putative Sensor histidine kinase; No homology to any previously reported sequences; 18076326. (1332 aa)
NIDE0557Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences. (949 aa)
NIDE0543Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences. (771 aa)
NIDE0542Protein of unknown function, putative Histidine kinase; No homology to any previously reported sequences. (910 aa)
cztSHeavy metal sensor histidine kinase; Function of strongly homologous gene; enzyme. (467 aa)
NIDE0241Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (532 aa)
NIDE0224Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (499 aa)
NIDE0222Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (545 aa)
NIDE0166Putative Histidine kinase with N-terminal NAD-binding region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (373 aa)
gyrBDNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (824 aa)
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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