STRINGSTRING
NIDE2649 NIDE2649 NIDE1870 NIDE1870 NIDE1879 NIDE1879 glnD glnD NIDE1085 NIDE1085 NIDE0687 NIDE0687 NIDE1024 NIDE1024 NIDE1584 NIDE1584 NIDE2816 NIDE2816 NIDE3049 NIDE3049 NIDE4196 NIDE4196 rny rny relA relA NIDE2199 NIDE2199 NIDE2324 NIDE2324 NIDE2415 NIDE2415
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NIDE2649Protein of unknown function, contains HD and HPt domains; No homology to any previously reported sequences; 11148031, 11489844, 11934609, 15476819, 9868367. (690 aa)
NIDE1870Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator. (392 aa)
NIDE1879Putative Metal dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (448 aa)
glnDPutative (Protein-PII) uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (894 aa)
NIDE1085Putative Metal dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (412 aa)
NIDE0687Response regulator with HD-GYP domain; Function of strongly homologous gene; regulator. (357 aa)
NIDE1024Protein of unknown function, putative HD-type Metal-dependent phosphohydrolase; No homology to any previously reported sequences. (251 aa)
NIDE1584Putative Response regulator with HD domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (380 aa)
NIDE2816Response regulator, CheY-like; Function of strongly homologous gene; regulator. (394 aa)
NIDE3049Conserved protein of unknown function, contains HD domain; Homologs of previously reported genes of unknown function. (473 aa)
NIDE4196Putative Phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (278 aa)
rny2',3'-cyclic-nucleotide 2'-phosphodiesterase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (525 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (727 aa)
NIDE2199Conserved protein of unknown function, contains HD domain; Homologs of previously reported genes of unknown function. (532 aa)
NIDE2324Putative Metal-dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (417 aa)
NIDE2415Putative Exopolyphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (517 aa)
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.