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gdhA gdhA argG argG argH argH NIDE1160 NIDE1160 ald ald glnA glnA purB purB purQ purQ purF purF putA putA pyrB pyrB carA carA carB carB aspC aspC asnB asnB asnB-2 asnB-2 glmS glmS NIDE2995 NIDE2995 asnB4 asnB4 gltD gltD gltB gltB purA purA nadB nadB iaaA iaaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gdhAGlutamate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)
argGArgininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
argHArgininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (484 aa)
NIDE1160Aminotransferase, class V; Function of strongly homologous gene; enzyme. (382 aa)
aldAlanine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the AlaDH/PNT family. (367 aa)
glnAGlutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (469 aa)
purBAdenylosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (444 aa)
purQPhosphoribosylformylglycinamidine synthase, PurQ subunit (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and P [...] (252 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (476 aa)
putABifunctional protein PutA; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (993 aa)
pyrBAspartate carbamoyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
carACarbamoyl-phosphate synthase, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family. (394 aa)
carBCarbamoyl-phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. (1089 aa)
aspCAspartate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (397 aa)
asnBAsparagine synthetase, glutamine-hydrolyzing; Function of strongly homologous gene; enzyme. (668 aa)
asnB-2Asparagine synthase (glutamine-hydrolyzing); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (631 aa)
glmSGlutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa)
NIDE2995Putative Asparagine synthetase (glutamine-hydrolyzing); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (645 aa)
asnB4Asparagine synthase (glutamine-hydrolyzing); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (610 aa)
gltDGlutamate synthase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa)
gltBGlutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1506 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (440 aa)
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (554 aa)
iaaAIsoaspartyl peptidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (312 aa)
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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