STRINGSTRING
ahcY ahcY metK metK NIDE0862 NIDE0862 asd asd ilvE ilvE NIDE1240 NIDE1240 NIDE1817 NIDE1817 cysK cysK metH metH NIDE2398 NIDE2398 aspC aspC mtnA mtnA cysE cysE NIDE3220 NIDE3220 NIDE3328 NIDE3328 mtnP mtnP serA serA mdh mdh NIDE3737 NIDE3737 lysC lysC hom hom
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (418 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (382 aa)
NIDE0862Putative Adenosylhomocysteine nucleosidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (267 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (304 aa)
NIDE1240Conserved protein of unknown function, putative 4Fe-4S ferredoxin; Homologs of previously reported genes of unknown function; 2600971, 3932661. (90 aa)
NIDE1817Homologs of previously reported genes of unknown function. (79 aa)
cysKCysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (309 aa)
metHMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa)
NIDE2398Putative Serine acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (150 aa)
aspCAspartate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (397 aa)
mtnA5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (343 aa)
cysESerine O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (216 aa)
NIDE3220Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (297 aa)
NIDE3328Putative Serine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (192 aa)
mtnPPutative S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (299 aa)
serAD-3-phosphoglycerate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (313 aa)
NIDE3737Putative Aminodeoxychorismate lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (293 aa)
lysCAspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (411 aa)
homHomoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (437 aa)
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.