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rsmG rsmG CDL18_12695 CDL18_12695 rsmI rsmI CDL18_05735 CDL18_05735 CDL25_02605 CDL25_02605 CDL18_09835 CDL18_09835 rplT rplT rlmH rlmH GCA_900067245_00268 GCA_900067245_00268 CDL18_03105 CDL18_03105 rnc rnc yhbY yhbY obg obg mrnC mrnC typA typA rnj rnj der der CDL20_00315 CDL20_00315 ybeY ybeY CDL27_00340 CDL27_00340 rsfS rsfS CDL27_00650 CDL27_00650 CDL23_07725 CDL23_07725 rsmD rsmD rbfA rbfA CDL18_08030 CDL18_08030 rimP rimP mraW mraW era era rsgA rsgA rlmN rlmN CDL25_13840 CDL25_13840 ylqF ylqF rimM rimM CDL18_04780 CDL18_04780 hydF hydF rsmA rsmA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rsmGUnannotated protein; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (237 aa)
CDL18_12695Unannotated protein. (71 aa)
rsmIUnannotated protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (281 aa)
CDL18_05735Unannotated protein; Belongs to the DEAD box helicase family. (527 aa)
CDL25_02605Unannotated protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (246 aa)
CDL18_09835Unannotated protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (148 aa)
rplTUnannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
rlmHUnannotated protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)
GCA_900067245_00268Unannotated protein. (30 aa)
CDL18_03105Unannotated protein. (175 aa)
rncUnannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (229 aa)
yhbYUnannotated protein. (96 aa)
obgUnannotated protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (427 aa)
mrnCUnannotated protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (155 aa)
typAUnannotated protein. (608 aa)
rnjUnannotated protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (554 aa)
derUnannotated protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (450 aa)
CDL20_00315Unannotated protein. (292 aa)
ybeYUnannotated protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (165 aa)
CDL27_00340Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
rsfSUnannotated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (116 aa)
CDL27_00650Unannotated protein; Belongs to the pseudouridine synthase RluA family. (321 aa)
CDL23_07725Unannotated protein; Belongs to the pseudouridine synthase RsuA family. (241 aa)
rsmDUnannotated protein. (189 aa)
rbfAUnannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (123 aa)
CDL18_08030Unannotated protein. (107 aa)
rimPUnannotated protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (155 aa)
mraWUnannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
eraUnannotated protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (299 aa)
rsgAUnannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (292 aa)
rlmNUnannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (346 aa)
CDL25_13840Unannotated protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (448 aa)
ylqFUnannotated protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (288 aa)
rimMUnannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (172 aa)
CDL18_04780Unannotated protein; Belongs to the pseudouridine synthase RsuA family. (252 aa)
hydFUnannotated protein. (397 aa)
rsmAUnannotated protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (291 aa)
Your Current Organism:
Ruminococcus gnavus
NCBI taxonomy Id: 33038
Other names: ATCC 29149, VPI C7-9, [. gnavus, [Ruminococcus] gnavus
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