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hisF_1 hisF_1 hisE hisE hisB hisB hisD hisD hisG hisG hisZ hisZ recU recU rluC rluC actIII actIII CUQ88406.1 CUQ88406.1 rsuA_2 rsuA_2 rsmF rsmF hisF_2 hisF_2 hisH1 hisH1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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hisF_1Imidazole glycerol phosphate synthase subunit HisF; Belongs to the HisA/HisF family. (257 aa)
hisEPhosphoribosyl-ATP pyrophosphatase; In the C-terminal section; belongs to the PRA-PH family. (426 aa)
hisBImidazoleglycerol-phosphate dehydratase. (196 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (214 aa)
hisZATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (419 aa)
recUHolliday junction resolvase recU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (177 aa)
rluCRibosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (342 aa)
actIIIPutative ketoacyl reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
CUQ88406.1Uncharacterized radical SAM protein YgiQ. (655 aa)
rsuA_2Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family. (241 aa)
rsmFRibosomal RNA small subunit methyltransferase F. (460 aa)
hisF_2Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
hisH1Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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