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pflB pflB pflA_1 pflA_1 pta pta ackA ackA acpP_1 acpP_1 maeB maeB pckA pckA fumB fumB ttdA_1 ttdA_1 dltB_1 dltB_1 CUQ84280.1 CUQ84280.1 tycC tycC lysA_3 lysA_3 CUQ84295.1 CUQ84295.1 prpC_1 prpC_1 dmdA_1 dmdA_1 ilvE ilvE CUQ84782.1 CUQ84782.1 acpA acpA ppsA ppsA ilvB ilvB ilvH_1 ilvH_1 bcrC bcrC atoA atoA DmdB_1 DmdB_1 dmdA_2 dmdA_2 DmdB_2 DmdB_2 hacA hacA hpdA hpdA csdB csdB fabG_3 fabG_3 adhE_2 adhE_2 CUQ87332.1 CUQ87332.1 accD accD accC accC fabZ fabZ accB accB fabF fabF fabG_4 fabG_4 fabD fabD CUQ87372.1 CUQ87372.1 acpP_2 acpP_2 fabH fabH yihX yihX porA porA leuA leuA fadD_2 fadD_2 CUQ88577.1 CUQ88577.1 gcdB gcdB gcdC gcdC CUQ88592.1 CUQ88592.1 accD5 accD5 ilvG ilvG ilvD ilvD leuB leuB ilvC ilvC ilvH_2 ilvH_2 mbtB mbtB lgrE lgrE lgrD lgrD ppdK ppdK fadD_3 fadD_3 acyP acyP CUQ92015.1 CUQ92015.1 prpC_2 prpC_2 CUQ92396.1 CUQ92396.1 fadK fadK scoA scoA fadB2 fadB2 thlA thlA ttdB ttdB ttdA_2 ttdA_2 frdB frdB nadB_2 nadB_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pflBFormate acetyltransferase. (750 aa)
pflA_1Pyruvate formate-lyase-activating enzyme. (248 aa)
ptaPhosphate acetyltransferase. (331 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
acpP_1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa)
maeBNADP-dependent malic enzyme. (382 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
fumBFumarate hydratase class I%2C anaerobic. (187 aa)
ttdA_1L(+)-tartrate dehydratase subunit alpha. (281 aa)
dltB_1D-alanyl-lipoteichoic acid biosynthesis protein DltB; Belongs to the membrane-bound acyltransferase family. (528 aa)
CUQ84280.1Uncharacterised protein. (329 aa)
tycCTyrocidine synthase III; Belongs to the ATP-dependent AMP-binding enzyme family. (532 aa)
lysA_3Diaminopimelate decarboxylase. (401 aa)
CUQ84295.1D-alanine--poly(phosphoribitol) ligase subunit 2. (75 aa)
prpC_12-methylcitrate synthase; Belongs to the citrate synthase family. (456 aa)
dmdA_12%2C3-dimethylmalate dehydratase large subunit. (756 aa)
ilvEBranched-chain-amino-acid aminotransferase. (341 aa)
CUQ84782.1Acyl-ACP thioesterase. (236 aa)
acpAAcyl carrier protein. (74 aa)
ppsAPlipastatin synthase subunit A. (472 aa)
ilvBAcetolactate synthase large subunit. (572 aa)
ilvH_1Acetolactate synthase isozyme 3 small subunit. (169 aa)
bcrCUndecaprenyl-diphosphatase BcrC. (191 aa)
atoAAcetate CoA-transferase subunit beta; Belongs to the 3-oxoacid CoA-transferase family. (503 aa)
DmdB_12%2C3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (159 aa)
dmdA_22%2C3-dimethylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (416 aa)
DmdB_22%2C3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
hacAHomoaconitase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (414 aa)
hpdA4-hydroxyphenylacetate decarboxylase activating enzyme. (264 aa)
csdB4-hydroxyphenylacetate decarboxylase large subunit. (843 aa)
fabG_33-oxoacyl-[acyl-carrier-protein] reductase FabG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa)
adhE_2Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (879 aa)
CUQ87332.1Homoprotocatechuate degradation operon regulator%2C HpaR. (148 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (572 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
fabZ(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (143 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
fabG_43-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
fabDMalonyl CoA-acyl carrier protein transacylase. (306 aa)
CUQ87372.1Nitronate monooxygenase. (312 aa)
acpP_2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (91 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase 3; Belongs to the thiolase-like superfamily. FabH family. (315 aa)
yihXPhosphatase yihX. (196 aa)
porAPyruvate synthase subunit porA. (1190 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (662 aa)
fadD_2Long-chain-fatty-acid--CoA ligase. (577 aa)
CUQ88577.1Methylmalonyl-CoA carboxyltransferase 5S subunit. (470 aa)
gcdBGlutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (383 aa)
gcdCGlutaconyl-CoA decarboxylase subunit gamma. (122 aa)
CUQ88592.1Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase%2C gamma subunit. (254 aa)
accD5Probable propionyl-CoA carboxylase beta chain 5. (479 aa)
ilvGAcetolactate synthase isozyme 2 large subunit. (561 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (557 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
ilvH_2Acetolactate synthase isozyme 3 small subunit. (165 aa)
mbtBPhenyloxazoline synthase MbtB. (508 aa)
lgrELinear gramicidin dehydrogenase LgrE. (250 aa)
lgrDLinear gramicidin synthase subunit D. (497 aa)
ppdKPyruvate%2C phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (876 aa)
fadD_3Long-chain-fatty-acid--CoA ligase. (583 aa)
acyPAcylphosphatase. (93 aa)
CUQ92015.1succinyl-CoA synthetase subunit alpha. (469 aa)
prpC_22-methylcitrate synthase; Belongs to the citrate synthase family. (459 aa)
CUQ92396.1Nitronate monooxygenase. (354 aa)
fadKShort-chain-fatty-acid--CoA ligase. (530 aa)
scoASuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit A; Belongs to the 3-oxoacid CoA-transferase family. (525 aa)
fadB23-hydroxybutyryl-CoA dehydrogenase. (292 aa)
thlAAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ttdBL(+)-tartrate dehydratase subunit beta. (208 aa)
ttdA_2L(+)-tartrate dehydratase subunit alpha. (299 aa)
frdBFumarate reductase iron-sulfur subunit. (225 aa)
nadB_2L-aspartate oxidase. (523 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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