(31 nodes) Branched-chain amino acid metabolic process, and Citrate cycle (TCA cycle) network (Ruminococcus torques)

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Your Input:
	maeB	NADP-dependent malic enzyme. (382 aa)
	pckA	Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
	fumB	Fumarate hydratase class I%2C anaerobic. (187 aa)
	ttdA_1	L(+)-tartrate dehydratase subunit alpha. (281 aa)
	prpC_1	2-methylcitrate synthase; Belongs to the citrate synthase family. (456 aa)
	dmdA_1	2%2C3-dimethylmalate dehydratase large subunit. (756 aa)
	ilvE	Branched-chain-amino-acid aminotransferase. (341 aa)
	ilvB	Acetolactate synthase large subunit. (572 aa)
	ilvH_1	Acetolactate synthase isozyme 3 small subunit. (169 aa)
	DmdB_1	2%2C3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (159 aa)
	dmdA_2	2%2C3-dimethylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (416 aa)
	DmdB_2	2%2C3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
	hacA	Homoaconitase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (414 aa)
	porA	Pyruvate synthase subunit porA. (1190 aa)
	leuA	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (662 aa)
	CUQ88577.1	Methylmalonyl-CoA carboxyltransferase 5S subunit. (470 aa)
	gcdB	Glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (383 aa)
	gcdC	Glutaconyl-CoA decarboxylase subunit gamma. (122 aa)
	CUQ88592.1	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase%2C gamma subunit. (254 aa)
	accD5	Probable propionyl-CoA carboxylase beta chain 5. (479 aa)
	ilvG	Acetolactate synthase isozyme 2 large subunit. (561 aa)
	ilvD	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (557 aa)
	leuB	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa)
	ilvC	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
	ilvH_2	Acetolactate synthase isozyme 3 small subunit. (165 aa)
	ppdK	Pyruvate%2C phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (876 aa)
	prpC_2	2-methylcitrate synthase; Belongs to the citrate synthase family. (459 aa)
	ttdB	L(+)-tartrate dehydratase subunit beta. (208 aa)
	ttdA_2	L(+)-tartrate dehydratase subunit alpha. (299 aa)
	frdB	Fumarate reductase iron-sulfur subunit. (225 aa)
	nadB_2	L-aspartate oxidase. (523 aa)

Your Current Organism:

Ruminococcus torques

NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUQ88577.1	CUQ88592.1	ERS852502_01808	ERS852502_01811	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase%2C gamma subunit.	0.704
CUQ88577.1	DmdB_1	ERS852502_01808	ERS852502_01351	Methylmalonyl-CoA carboxyltransferase 5S subunit.	2%2C3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.	0.815
CUQ88577.1	DmdB_2	ERS852502_01808	ERS852502_01353	Methylmalonyl-CoA carboxyltransferase 5S subunit.	2%2C3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.	0.815
CUQ88577.1	accD5	ERS852502_01808	ERS852502_01812	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Probable propionyl-CoA carboxylase beta chain 5.	0.793
CUQ88577.1	dmdA_2	ERS852502_01808	ERS852502_01352	Methylmalonyl-CoA carboxyltransferase 5S subunit.	2%2C3-dimethylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.800
CUQ88577.1	gcdB	ERS852502_01808	ERS852502_01809	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).	0.997
CUQ88577.1	gcdC	ERS852502_01808	ERS852502_01810	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Glutaconyl-CoA decarboxylase subunit gamma.	0.968
CUQ88577.1	hacA	ERS852502_01808	ERS852502_01354	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Homoaconitase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.800
CUQ88577.1	ilvG	ERS852502_01808	ERS852502_01817	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Acetolactate synthase isozyme 2 large subunit.	0.810
CUQ88577.1	ilvH_1	ERS852502_01808	ERS852502_01206	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Acetolactate synthase isozyme 3 small subunit.	0.800
CUQ88577.1	ilvH_2	ERS852502_01808	ERS852502_01921	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Acetolactate synthase isozyme 3 small subunit.	0.800
CUQ88577.1	leuA	ERS852502_01808	ERS852502_01671	Methylmalonyl-CoA carboxyltransferase 5S subunit.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.	0.810
CUQ88577.1	maeB	ERS852502_01808	ERS852502_00323	Methylmalonyl-CoA carboxyltransferase 5S subunit.	NADP-dependent malic enzyme.	0.912
CUQ88577.1	pckA	ERS852502_01808	ERS852502_00434	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.	0.914
CUQ88577.1	porA	ERS852502_01808	ERS852502_01562	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Pyruvate synthase subunit porA.	0.980
CUQ88577.1	ppdK	ERS852502_01808	ERS852502_02133	Methylmalonyl-CoA carboxyltransferase 5S subunit.	Pyruvate%2C phosphate dikinase; Belongs to the PEP-utilizing enzyme family.	0.917
CUQ88577.1	prpC_1	ERS852502_01808	ERS852502_00938	Methylmalonyl-CoA carboxyltransferase 5S subunit.	2-methylcitrate synthase; Belongs to the citrate synthase family.	0.819
CUQ88577.1	prpC_2	ERS852502_01808	ERS852502_02551	Methylmalonyl-CoA carboxyltransferase 5S subunit.	2-methylcitrate synthase; Belongs to the citrate synthase family.	0.819
CUQ88577.1	ttdA_2	ERS852502_01808	ERS852502_02787	Methylmalonyl-CoA carboxyltransferase 5S subunit.	L(+)-tartrate dehydratase subunit alpha.	0.828
CUQ88577.1	ttdB	ERS852502_01808	ERS852502_02786	Methylmalonyl-CoA carboxyltransferase 5S subunit.	L(+)-tartrate dehydratase subunit beta.	0.828