node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ilvB | ilvC | ERS852502_01205 | ERS852502_01920 | Acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.940 |
ilvB | ilvD | ERS852502_01205 | ERS852502_01818 | Acetolactate synthase large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.959 |
ilvB | ilvH_1 | ERS852502_01205 | ERS852502_01206 | Acetolactate synthase large subunit. | Acetolactate synthase isozyme 3 small subunit. | 0.990 |
ilvB | ilvH_2 | ERS852502_01205 | ERS852502_01921 | Acetolactate synthase large subunit. | Acetolactate synthase isozyme 3 small subunit. | 0.974 |
ilvC | ilvB | ERS852502_01920 | ERS852502_01205 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase large subunit. | 0.940 |
ilvC | ilvD | ERS852502_01920 | ERS852502_01818 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.997 |
ilvC | ilvG | ERS852502_01920 | ERS852502_01817 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase isozyme 2 large subunit. | 0.994 |
ilvC | ilvH_1 | ERS852502_01920 | ERS852502_01206 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase isozyme 3 small subunit. | 0.994 |
ilvC | ilvH_2 | ERS852502_01920 | ERS852502_01921 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase isozyme 3 small subunit. | 0.997 |
ilvD | ilvB | ERS852502_01818 | ERS852502_01205 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase large subunit. | 0.959 |
ilvD | ilvC | ERS852502_01818 | ERS852502_01920 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.997 |
ilvD | ilvG | ERS852502_01818 | ERS852502_01817 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase isozyme 2 large subunit. | 0.987 |
ilvD | ilvH_1 | ERS852502_01818 | ERS852502_01206 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase isozyme 3 small subunit. | 0.883 |
ilvD | ilvH_2 | ERS852502_01818 | ERS852502_01921 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase isozyme 3 small subunit. | 0.898 |
ilvG | ilvC | ERS852502_01817 | ERS852502_01920 | Acetolactate synthase isozyme 2 large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.994 |
ilvG | ilvD | ERS852502_01817 | ERS852502_01818 | Acetolactate synthase isozyme 2 large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.987 |
ilvG | ilvH_1 | ERS852502_01817 | ERS852502_01206 | Acetolactate synthase isozyme 2 large subunit. | Acetolactate synthase isozyme 3 small subunit. | 0.997 |
ilvG | ilvH_2 | ERS852502_01817 | ERS852502_01921 | Acetolactate synthase isozyme 2 large subunit. | Acetolactate synthase isozyme 3 small subunit. | 0.997 |
ilvH_1 | ilvB | ERS852502_01206 | ERS852502_01205 | Acetolactate synthase isozyme 3 small subunit. | Acetolactate synthase large subunit. | 0.990 |
ilvH_1 | ilvC | ERS852502_01206 | ERS852502_01920 | Acetolactate synthase isozyme 3 small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.994 |