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guaB guaB purC purC purF purF purB purB glyA glyA purL purL CUQ81864.1 CUQ81864.1 purH purH ybbW ybbW hyuA hyuA pyrI pyrI pyrB pyrB gmk_1 gmk_1 CUQ84924.1 CUQ84924.1 guaD guaD xanQ xanQ carA carA carB carB CUQ87592.1 CUQ87592.1 fhs fhs folD folD yfkN_1 yfkN_1 udk udk purA purA pyrC pyrC xpt xpt purD purD purN purN purM purM purE purE pyrE pyrE pyrD pyrD pyrK_2 pyrK_2 pyrF pyrF guaA_1 guaA_1 yfkN_2 yfkN_2 udp_2 udp_2 upp upp gmk_3 gmk_3 CUQ93278.1 CUQ93278.1 punA punA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
gene fusions
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textmining
co-expression
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guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (291 aa)
purFAmidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa)
glyAPyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
purLPhosphoribosylformylglycinamidine synthase. (1251 aa)
CUQ81864.1IMP cyclohydrolase. (237 aa)
purHBifunctional purine biosynthesis protein PurH. (392 aa)
ybbWAllantoin transport protein. (485 aa)
hyuAD-phenylhydantoinase. (463 aa)
pyrIAspartate carbamoyltransferase regulatory chain. (146 aa)
pyrBAspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
gmk_1Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (211 aa)
CUQ84924.1Uncharacterised protein. (456 aa)
guaDGuanine deaminase. (424 aa)
xanQXanthine permease XanQ. (480 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (374 aa)
carBCarbamoyl-phosphate synthase large chain. (1067 aa)
CUQ87592.1Xanthine permease. (73 aa)
fhsFormate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
folDBifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa)
yfkN_1Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. (649 aa)
udkUridine kinase. (573 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (426 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (422 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (197 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (208 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (341 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (226 aa)
pyrDDihydroorotate dehydrogenase B (NAD(+))%2C catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (300 aa)
pyrK_2Dihydrdoorotate oxidase B%2C electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (260 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (309 aa)
guaA_1GMP synthase [glutamine-hydrolyzing]. (515 aa)
yfkN_2Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. (620 aa)
udp_2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (260 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
gmk_3Guanylate kinase. (194 aa)
CUQ93278.1Adenine deaminase. (328 aa)
punAPurine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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