STRINGSTRING
dxr dxr hom_2 hom_2 panE panE hom_1 hom_1 aroE_1 aroE_1 CUQ92546.1 CUQ92546.1 fucO fucO aroE_2 aroE_2 gutB_2 gutB_2 guaB guaB algD algD maeB maeB gpsA gpsA dhaD dhaD bdhA_1 bdhA_1 dhaT dhaT CUQ84441.1 CUQ84441.1 murB murB bdhA_2 bdhA_2 fadB2 fadB2 ilvC ilvC leuB leuB serA_1 serA_1 icd icd hisD hisD gldA gldA strL strL adhE_3 adhE_3 adhE_2 adhE_2 gutB_1 gutB_1 aroE_3 aroE_3 adhE_1 adhE_1 serA_2 serA_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa)
hom_2Homoserine dehydrogenase. (405 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (318 aa)
hom_1Homoserine dehydrogenase. (425 aa)
aroE_1Shikimate dehydrogenase. (291 aa)
CUQ92546.1Putative 2-hydroxyacid dehydrogenase HI_1556; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
fucOLactaldehyde reductase. (381 aa)
aroE_2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (291 aa)
gutB_2Sorbitol dehydrogenase. (342 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
algDGDP-mannose 6-dehydrogenase. (437 aa)
maeBNADP-dependent malic enzyme. (382 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (337 aa)
dhaDGlycerol dehydrogenase. (365 aa)
bdhA_1NADH-dependent butanol dehydrogenase A. (395 aa)
dhaT1%2C3-propanediol dehydrogenase. (423 aa)
CUQ84441.12-dehydropantoate 2-reductase. (300 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (301 aa)
bdhA_2NADH-dependent butanol dehydrogenase A. (396 aa)
fadB23-hydroxybutyryl-CoA dehydrogenase. (292 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (339 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa)
serA_1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (387 aa)
icdIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (398 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
gldAGlycerol dehydrogenase. (362 aa)
strLdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (283 aa)
adhE_3Aldehyde-alcohol dehydrogenase. (393 aa)
adhE_2Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (879 aa)
gutB_1Sorbitol dehydrogenase. (404 aa)
aroE_3Shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. (104 aa)
adhE_1Aldehyde-alcohol dehydrogenase. (382 aa)
serA_2D-3-phosphoglycerate dehydrogenase. (316 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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