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| | bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa) |
| | CUQ80490.1 | Conserved hypothetical integral membrane protein. (203 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (167 aa) |
| | mog_1 | Molybdopterin adenylyltransferase. (174 aa) |
| | moaA_1 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | thiI | Probable tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (396 aa) |
| | sigK | RNA polymerase sigma-28 factor precursor. (205 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (291 aa) |
| | pdxK | Pyridoxine kinase. (277 aa) |
| | dacA | DNA integrity scanning protein DisA; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (288 aa) |
| | dapH | 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxy late N-acetyltransferase. (189 aa) |
| | CUQ81095.1 | RNA polymerase sigma factor%2C sigma-70 family. (139 aa) |
| | sigE | RNA polymerase sigma-35 factor precursor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (246 aa) |
| | sigF_1 | Stage II sporulation protein AC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (260 aa) |
| | CUQ81282.1 | Cytidylate kinase. (161 aa) |
| | purF | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (871 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (194 aa) |
| | CUQ81439.1 | ACT domain-containing protein; Belongs to the UPF0237 family. (90 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (446 aa) |
| | polC_1 | DNA polymerase III polC-type. (1519 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase. (1251 aa) |
| | CUQ81864.1 | IMP cyclohydrolase. (237 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH. (392 aa) |
| | pdxT | Glutamine amidotransferase subunit pdxT. (192 aa) |
| | pdxS | Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa) |
| | queH | Uncharacterized BCR%2C COG1636; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (212 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase. (341 aa) |
| | CUQ82121.1 | Cobalamin biosynthesis protein CbiG. (382 aa) |
| | cobK | Precorrin-6A reductase. (282 aa) |
| | btuR | Cob(I)yrinic acid a%2Cc-diamide adenosyltransferase. (175 aa) |
| | cbiD | cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (389 aa) |
| | cbiL | Cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. (252 aa) |
| | cbiF | Cobalt-precorrin-4 C(11)-methyltransferase. (276 aa) |
| | cbiH | Cobalt-precorrin-3B C(17)-methyltransferase. (243 aa) |
| | cbiT | Probable cobalt-precorrin-6Y C(15)-methyltransferase [decarboxylating]. (426 aa) |
| | cobB_1 | Cobyrinic acid A%2CC-diamide synthase. (494 aa) |
| | cobT | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (398 aa) |
| | cobS | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (250 aa) |
| | cobD | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (330 aa) |
| | cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (502 aa) |
| | bioD1 | ATP-dependent dethiobiotin synthetase BioD 1; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (227 aa) |
| | bioF | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily. (644 aa) |
| | sigV_1 | RNA polymerase sigma factor sigV; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa) |
| | cobU | Adenosylcobinamide kinase. (330 aa) |
| | cbiC | Cobalt-precorrin-8X methylmutase. (211 aa) |
| | fgs_1 | Folylpolyglutamate synthase. (436 aa) |
| | folE | GTP cyclohydrolase 1. (185 aa) |
| | folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (271 aa) |
| | sulD | Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (278 aa) |
| | CUQ82412.1 | Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (179 aa) |
| | CUQ82494.1 | DNA polymerase III subunit delta. (345 aa) |
| | hemZ_1 | Oxygen-independent coproporphyrinogen-III oxidase 2; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (385 aa) |
| | CUQ82526.1 | Nitrous oxide-stimulated promoter. (112 aa) |
| | glmU | Bifunctional protein GlmU. (224 aa) |
| | prs_1 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (392 aa) |
| | mog_2 | Molybdopterin adenylyltransferase. (155 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory chain. (146 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa) |
| | gmk_1 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (211 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (81 aa) |
| | ygaD | Competence damage-inducible protein A; Belongs to the CinA family. (174 aa) |
| | CUQ82996.1 | Queuosine biosynthesis protein QueD. (140 aa) |
| | queE | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (216 aa) |
| | queC | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (227 aa) |
| | queF | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (160 aa) |
| | thiE | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (215 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa) |
| | CUQ83359.1 | RNA polymerase sigma factor. (139 aa) |
| | dnaX_1 | DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (530 aa) |
| | sigM_1 | RNA polymerase sigma factor sigM; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (369 aa) |
| | serS | Serine--tRNA ligase. (429 aa) |
| | CUQ84017.1 | RNA polymerase factor sigma-70. (187 aa) |
| | polC_2 | DNA polymerase III polC-type. (231 aa) |
| | coaBC | DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa) |
| | coaX | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa) |
| | CUQ84365.1 | Uncharacterised protein. (178 aa) |
| | ywpJ_1 | Uncharacterized phosphatase YwpJ. (258 aa) |
| | CUQ84425.1 | Flavodoxin. (167 aa) |
| | CUQ84433.1 | Cytidylate kinase. (194 aa) |
| | prs_2 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (394 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1234 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1287 aa) |
| | nusG | Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (172 aa) |
| | supH | Sugar phosphatase SupH. (265 aa) |
| | udp_1 | Uridine phosphorylase. (260 aa) |
| | gmk_2 | Guanylate kinase. (224 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (331 aa) |
| | murAB | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (430 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa) |
| | nadC | Probable nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (284 aa) |
| | nadA | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (301 aa) |
| | sigM_2 | RNA polymerase sigma factor sigM; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (767 aa) |
| | hemZ_2 | Oxygen-independent coproporphyrinogen-III oxidase 2. (470 aa) |
| | thyA1 | Thymidylate synthase 1. (282 aa) |
| | dfrD | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa) |
| | nadE | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (638 aa) |
| | CUQ85841.1 | Putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein. (338 aa) |
| | proB | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (265 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa) |
| | thiS | Thiamine biosynthesis protein ThiS. (65 aa) |
| | moeB | Molybdopterin-synthase adenylyltransferase. (215 aa) |
| | thiG | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (257 aa) |
| | thiH_1 | 2-iminoacetate synthase. (404 aa) |
| | tenI | Regulatory protein tenI. (186 aa) |
| | CUQ86270.1 | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase. (254 aa) |
| | sigA_1 | Sigma-A; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (280 aa) |
| | thiC | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (436 aa) |
| | CUQ86516.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase. (263 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (231 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (374 aa) |
| | carB | Carbamoyl-phosphate synthase large chain. (1067 aa) |
| | sigF_2 | Stage II sporulation protein AC; Belongs to the sigma-70 factor family. (78 aa) |
| | fgs_2 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (432 aa) |
| | CUQ86866.1 | Uncharacterized conserved protein. (173 aa) |
| | CUQ86891.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase. (267 aa) |
| | ywaC_1 | GTP pyrophosphokinase ywaC. (258 aa) |
| | yidA_1 | Phosphatase YidA. (277 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha. (319 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | selA | L-seryl-tRNA(Sec) selenium transferase. (515 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (572 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | thiN | Thiamine pyrophosphokinase. (219 aa) |
| | priA | Primosomal protein N'. (741 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (411 aa) |
| | thiD | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (269 aa) |
| | CUQ87846.1 | RNA polymerase sigma factor WhiG. (147 aa) |
| | folD | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa) |
| | pyrK_1 | Dihydrdoorotate oxidase B%2C electron transfer subunit. (295 aa) |
| | CUQ88227.1 | Cytidylate kinase. (216 aa) |
| | CUQ88247.1 | Putative nicotinate-nucleotide adenylyltransferase. (191 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase. (226 aa) |
| | CUQ88340.1 | Uncharacterized conserved protein. (83 aa) |
| | CUQ88346.1 | Uncharacterized conserved protein. (64 aa) |
| | strL | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (283 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (163 aa) |
| | cmk | Cytidylate kinase. (219 aa) |
| | accD5 | Probable propionyl-CoA carboxylase beta chain 5. (479 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (375 aa) |
| | yjiA_1 | Uncharacterized GTP-binding protein YjiA. (337 aa) |
| | ppnK | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (277 aa) |
| | dxs_2 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (625 aa) |
| | nusB | N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (139 aa) |
| | ribF | Riboflavin biosynthesis protein ribF; Belongs to the ribF family. (303 aa) |
| | nusA | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. (398 aa) |
| | udk | Uridine kinase. (573 aa) |
| | sigA_2 | Sigma-A; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (373 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (592 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (172 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (426 aa) |
| | sigH | Stage 0 sporulation protein H; Belongs to the sigma-70 factor family. (203 aa) |
| | CUQ89606.1 | Conserved hypothetical integral membrane protein. (193 aa) |
| | CUQ89691.1 | C_GCAxxG_C_C family protein. (137 aa) |
| | CUQ89787.1 | DNA primase (bacterial type). (323 aa) |
| | CUQ89804.1 | Uncharacterised protein. (115 aa) |
| | CUQ90036.1 | RNA polymerase sigma factor%2C sigma-70 family. (143 aa) |
| | proA_1 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa) |
| | CUQ90331.1 | Bacterial regulatory proteins%2C luxR family. (144 aa) |
| | CUQ90352.1 | Nitrous oxide-stimulated promoter. (113 aa) |
| | CUQ90431.1 | DNA primase (bacterial type). (325 aa) |
| | CUQ90564.1 | Ferredoxin I. (203 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (422 aa) |
| | bacD | Alanine-anticapsin ligase BacD. (405 aa) |
| | spoT | Bifunctional (p)ppGpp synthase/hydrolase SpoT. (172 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | thiH_2 | 2-iminoacetate synthase. (357 aa) |
| | xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (197 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (208 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (341 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (226 aa) |
| | pyrD | Dihydroorotate dehydrogenase B (NAD(+))%2C catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (300 aa) |
| | pyrK_2 | Dihydrdoorotate oxidase B%2C electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (260 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (309 aa) |
| | ntpD | V-type sodium pump subunit D. (220 aa) |
| | ntpB_1 | V-type sodium pump subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (457 aa) |
| | ntpA | V-type sodium ATPase catalytic subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (588 aa) |
| | ntpG | V-type sodium pump subunit G. (108 aa) |
| | atpE-2 | V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (200 aa) |
| | atpC | F-ATPase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa) |
| | atpD_1 | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (464 aa) |
| | atpG | Na(+)-translocating ATPase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (296 aa) |
| | atpA_1 | ATP synthase subunit alpha. (502 aa) |
| | atpH | F-type ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa) |
| | atpF | F-type ATPase subunit b. (156 aa) |
| | atpE | Lipid-binding protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa) |
| | atpB | F-ATPase subunit 6; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (248 aa) |
| | yjiA_2 | Uncharacterized GTP-binding protein YjiA. (383 aa) |
| | cbiK | Sirohydrochlorin cobaltochelatase. (398 aa) |
| | guaA_1 | GMP synthase [glutamine-hydrolyzing]. (515 aa) |
| | guaA_2 | GMP synthase [glutamine-hydrolyzing]. (70 aa) |
| | CUQ92359.1 | RNA polymerase factor sigma-70. (206 aa) |
| | ywaC_2 | GTP pyrophosphokinase ywaC. (262 aa) |
| | trpE | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (509 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (269 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (226 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa) |
| | CUQ92500.1 | Cytidylate kinase. (209 aa) |
| | yidA_2 | Phosphatase YidA. (270 aa) |
| | pncB2 | Nicotinate phosphoribosyltransferase 2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (482 aa) |
| | dnaE | DNA polymerase III subunit alpha. (1157 aa) |
| | atpD_2 | V-ATPase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (209 aa) |
| | ntpB_2 | V-type sodium pump subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (461 aa) |
| | atpA_2 | V-type ATP synthase alpha chain. (589 aa) |
| | CUQ92716.1 | V-type ATP synthase subunit E. (195 aa) |
| | CUQ92723.1 | V-type ATP synthase subunit K. (146 aa) |
| | sigV_2 | RNA polymerase sigma factor sigV; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa) |
| | dnaC | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (451 aa) |
| | ywpJ_2 | Uncharacterized phosphatase YwpJ. (296 aa) |
| | yidA_3 | Phosphatase YidA. (274 aa) |
| | yqgN | 5-formyltetrahydrofolate cyclo-ligase family protein. (197 aa) |
| | CUQ93038.1 | Cytidylate kinase. (208 aa) |
| | udp_2 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (260 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | dnaX_2 | DNA polymerase III subunit tau. (331 aa) |
| | CUQ93278.1 | Adenine deaminase. (328 aa) |
| | CUQ93286.1 | 5'-nucleotidase. (195 aa) |
