(5 nodes) GMP metabolic process network (Ruminococcus torques)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	guaA_2	GMP synthase [glutamine-hydrolyzing]. (70 aa)
	guaA_1	GMP synthase [glutamine-hydrolyzing]. (515 aa)
	guaB	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
	gmk_1	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (211 aa)
	gmk_2	Guanylate kinase. (224 aa)

Your Current Organism:

Ruminococcus torques

NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gmk_1	guaA_1	ERS852502_00622	ERS852502_02502	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP synthase [glutamine-hydrolyzing].	0.508
gmk_1	guaA_2	ERS852502_00622	ERS852502_02533	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP synthase [glutamine-hydrolyzing].	0.419
gmk_2	guaA_1	ERS852502_01042	ERS852502_02502	Guanylate kinase.	GMP synthase [glutamine-hydrolyzing].	0.521
gmk_2	guaA_2	ERS852502_01042	ERS852502_02533	Guanylate kinase.	GMP synthase [glutamine-hydrolyzing].	0.492
guaA_1	gmk_1	ERS852502_02502	ERS852502_00622	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.508
guaA_1	gmk_2	ERS852502_02502	ERS852502_01042	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase.	0.521
guaA_1	guaB	ERS852502_02502	ERS852502_00100	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA_2	gmk_1	ERS852502_02533	ERS852502_00622	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.419
guaA_2	gmk_2	ERS852502_02533	ERS852502_01042	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase.	0.492
guaA_2	guaB	ERS852502_02533	ERS852502_00100	GMP synthase [glutamine-hydrolyzing].	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaB	guaA_1	ERS852502_00100	ERS852502_02502	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase [glutamine-hydrolyzing].	0.999
guaB	guaA_2	ERS852502_00100	ERS852502_02533	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase [glutamine-hydrolyzing].	0.999