STRINGSTRING
tadA tadA purD purD CUQ91123.1 CUQ91123.1 nth nth yabJ yabJ thiH_2 thiH_2 nudC nudC CUQ90533.1 CUQ90533.1 ltrA_2 ltrA_2 dinG_3 dinG_3 dinG_2 dinG_2 ltrA_1 ltrA_1 CUQ89653.1 CUQ89653.1 lgrD lgrD mbtB mbtB mrnC mrnC rplT rplT CUQ89305.1 CUQ89305.1 ribF ribF CUQ89063.1 CUQ89063.1 CUQ88986.1 CUQ88986.1 CUQ88968.1 CUQ88968.1 iolC_1 iolC_1 serC serC nadD nadD ybeY ybeY fhs fhs mdeA_1 mdeA_1 leuA leuA ravA ravA truA_2 truA_2 engD engD fabF fabF abgB abgB rplV rplV rplP rplP adk adk CUQ86196.1 CUQ86196.1 rbgA rbgA truA_1 truA_1 CUQ85820.1 CUQ85820.1 nadC nadC CUQ85250.1 CUQ85250.1 bioB bioB fadD_1 fadD_1 ispE ispE sbcD sbcD moeZ moeZ tktA tktA CUQ83120.1 CUQ83120.1 CUQ83090.1 CUQ83090.1 lip2 lip2 CUQ82996.1 CUQ82996.1 dhaD dhaD argB argB argC argC CUQ82407.1 CUQ82407.1 CUQ82337.1 CUQ82337.1 nifH1_2 nifH1_2 nifH1_1 nifH1_1 hyuA hyuA pdxS pdxS rnz rnz yxeP yxeP dinG_1 dinG_1 rarA rarA CUQ81436.1 CUQ81436.1 nifS nifS purF purF CUQ81248.1 CUQ81248.1 CUQ81122.1 CUQ81122.1 gltB gltB nfo nfo yrrK yrrK iscS iscS speB speB ntpB_1 ntpB_1 ntpG ntpG ntpC ntpC gldA gldA CUQ91402.1 CUQ91402.1 truA_3 truA_3 iolC_2 iolC_2 CUQ91669.1 CUQ91669.1 CUQ91681.1 CUQ91681.1 ubiB ubiB fadB2 fadB2 ntpB_2 ntpB_2 CUQ92719.1 CUQ92719.1 CUQ92731.1 CUQ92731.1 fieF fieF frlD_1 frlD_1 CUQ92944.1 CUQ92944.1 frlD_2 frlD_2 CUQ92967.1 CUQ92967.1 CUQ93278.1 CUQ93278.1 mdeA_2 mdeA_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (165 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
CUQ91123.1Thioredoxin C-1; Belongs to the thioredoxin family. (102 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa)
yabJEnamine/imine deaminase. (124 aa)
thiH_22-iminoacetate synthase. (357 aa)
nudCNADH pyrophosphatase. (278 aa)
CUQ90533.1Peptidase M16C associated. (974 aa)
ltrA_2Group II intron-encoded protein ltrA. (601 aa)
dinG_3Probable ATP-dependent helicase dinG homolog. (655 aa)
dinG_2Probable ATP-dependent helicase dinG homolog. (657 aa)
ltrA_1Group II intron-encoded protein ltrA. (607 aa)
CUQ89653.1Retron-type reverse transcriptase. (207 aa)
lgrDLinear gramicidin synthase subunit D. (497 aa)
mbtBPhenyloxazoline synthase MbtB. (508 aa)
mrnCMini-ribonuclease 3; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (158 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
CUQ89305.1Multidrug resistance protein MdtN. (451 aa)
ribFRiboflavin biosynthesis protein ribF; Belongs to the ribF family. (303 aa)
CUQ89063.1Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (296 aa)
CUQ88986.1Calcium-transporting ATPase lmo0841. (870 aa)
CUQ88968.1Calcium-transporting ATPase lmo0841. (823 aa)
iolC_15-dehydro-2-deoxygluconokinase. (323 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)
nadDNicotinate-nucleotide adenylyltransferase. (226 aa)
ybeYProbable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (165 aa)
fhsFormate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
mdeA_1Methionine gamma-lyase. (425 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (662 aa)
ravAATPase ravA. (314 aa)
truA_2tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (250 aa)
engDGTP-dependent nucleic acid-binding protein engD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
abgBAminobenzoyl-glutamate utilization protein B. (438 aa)
rplV50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (128 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (145 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
CUQ86196.1Uncharacterized protein conserved in bacteria. (412 aa)
rbgARibosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (282 aa)
truA_1tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (260 aa)
CUQ85820.1Magnesium transporter mgtE; Acts as a magnesium transporter. (443 aa)
nadCProbable nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (284 aa)
CUQ85250.1Homoserine kinase. (361 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (331 aa)
fadD_1Long-chain-fatty-acid--CoA ligase. (510 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (291 aa)
sbcDNuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (386 aa)
moeZProbable adenylyltransferase/sulfurtransferase MoeZ. (252 aa)
tktATransketolase 1. (278 aa)
CUQ83120.1Flavodoxin. (156 aa)
CUQ83090.1Transcriptional regulator FixK. (230 aa)
lip2Lipase 2. (316 aa)
CUQ82996.1Queuosine biosynthesis protein QueD. (140 aa)
dhaDGlycerol dehydrogenase. (365 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (300 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa)
CUQ82407.1RNA 2'-phosphotransferase. (182 aa)
CUQ82337.1Ribonuclease Z. (266 aa)
nifH1_2Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family. (258 aa)
nifH1_1Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family. (255 aa)
hyuAD-phenylhydantoinase. (463 aa)
pdxSPyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (302 aa)
yxePUncharacterized hydrolase YxeP. (392 aa)
dinG_1Probable ATP-dependent helicase dinG homolog. (785 aa)
rarAReplication-associated recombination protein A. (438 aa)
CUQ81436.1Putative hydrolase. (265 aa)
nifSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (396 aa)
purFAmidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa)
CUQ81248.1Ribonuclease TTHA0252. (534 aa)
CUQ81122.1Putative protein-S-isoprenylcysteine methyltransferase. (203 aa)
gltBFerredoxin-dependent glutamate synthase 1. (1507 aa)
nfoProbable endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (301 aa)
yrrKPutative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (152 aa)
iscSCysteine desulfurase. (385 aa)
speBAgmatinase; Belongs to the arginase family. (285 aa)
ntpB_1V-type sodium pump subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (457 aa)
ntpGV-type sodium pump subunit G. (108 aa)
ntpCV-type sodium pump subunit C. (324 aa)
gldAGlycerol dehydrogenase. (362 aa)
CUQ91402.1Predicted aminopeptidase%2C Iap family. (701 aa)
truA_3tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (244 aa)
iolC_25-dehydro-2-deoxygluconokinase. (319 aa)
CUQ91669.1Beta-lactamase superfamily domain. (228 aa)
CUQ91681.1G:T/U mismatch-specific DNA glycosylase. (162 aa)
ubiBProbable ubiquinone biosynthesis protein UbiB. (527 aa)
fadB23-hydroxybutyryl-CoA dehydrogenase. (292 aa)
ntpB_2V-type sodium pump subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (461 aa)
CUQ92719.1V-type ATP synthase subunit F. (102 aa)
CUQ92731.1V-type ATP synthase subunit C. (348 aa)
fieFFerrous-iron efflux pump FieF; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (306 aa)
frlD_1Fructosamine kinase frlD. (264 aa)
CUQ92944.1Uncharacterized conserved protein. (142 aa)
frlD_2Fructosamine kinase frlD. (263 aa)
CUQ92967.1Uncharacterized conserved protein%2C contains double-stranded beta-helix domain. (117 aa)
CUQ93278.1Adenine deaminase. (328 aa)
mdeA_2Methionine gamma-lyase. (435 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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