(10 nodes) ACT domain network (Ruminococcus torques)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ilvH_2	Acetolactate synthase isozyme 3 small subunit. (165 aa)
	serA_1	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (387 aa)
	thrA	Aspartokinase I/homoserine dehydrogenase I; Belongs to the aspartokinase family. (439 aa)
	ilvH_1	Acetolactate synthase isozyme 3 small subunit. (169 aa)
	hom_1	Homoserine dehydrogenase. (425 aa)
	relA	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (767 aa)
	CUQ81439.1	ACT domain-containing protein; Belongs to the UPF0237 family. (90 aa)
	tdcB	L-threonine dehydratase catabolic TdcB. (404 aa)
	sdhB	L-serine dehydratase%2C beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (222 aa)
	pheA	P-protein. (380 aa)

Your Current Organism:

Ruminococcus torques

NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hom_1	ilvH_1	ERS852502_01199	ERS852502_01206	Homoserine dehydrogenase.	Acetolactate synthase isozyme 3 small subunit.	0.735
hom_1	ilvH_2	ERS852502_01199	ERS852502_01921	Homoserine dehydrogenase.	Acetolactate synthase isozyme 3 small subunit.	0.678
hom_1	pheA	ERS852502_01199	ERS852502_00617	Homoserine dehydrogenase.	P-protein.	0.424
hom_1	sdhB	ERS852502_01199	ERS852502_00864	Homoserine dehydrogenase.	L-serine dehydratase%2C beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.841
hom_1	serA_1	ERS852502_01199	ERS852502_01815	Homoserine dehydrogenase.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.464
hom_1	thrA	ERS852502_01199	ERS852502_01743	Homoserine dehydrogenase.	Aspartokinase I/homoserine dehydrogenase I; Belongs to the aspartokinase family.	0.595
ilvH_1	hom_1	ERS852502_01206	ERS852502_01199	Acetolactate synthase isozyme 3 small subunit.	Homoserine dehydrogenase.	0.735
ilvH_1	ilvH_2	ERS852502_01206	ERS852502_01921	Acetolactate synthase isozyme 3 small subunit.	Acetolactate synthase isozyme 3 small subunit.	0.914
ilvH_1	pheA	ERS852502_01206	ERS852502_00617	Acetolactate synthase isozyme 3 small subunit.	P-protein.	0.661
ilvH_1	tdcB	ERS852502_01206	ERS852502_00315	Acetolactate synthase isozyme 3 small subunit.	L-threonine dehydratase catabolic TdcB.	0.950
ilvH_2	hom_1	ERS852502_01921	ERS852502_01199	Acetolactate synthase isozyme 3 small subunit.	Homoserine dehydrogenase.	0.678
ilvH_2	ilvH_1	ERS852502_01921	ERS852502_01206	Acetolactate synthase isozyme 3 small subunit.	Acetolactate synthase isozyme 3 small subunit.	0.914
ilvH_2	pheA	ERS852502_01921	ERS852502_00617	Acetolactate synthase isozyme 3 small subunit.	P-protein.	0.631
ilvH_2	tdcB	ERS852502_01921	ERS852502_00315	Acetolactate synthase isozyme 3 small subunit.	L-threonine dehydratase catabolic TdcB.	0.950
pheA	hom_1	ERS852502_00617	ERS852502_01199	P-protein.	Homoserine dehydrogenase.	0.424
pheA	ilvH_1	ERS852502_00617	ERS852502_01206	P-protein.	Acetolactate synthase isozyme 3 small subunit.	0.661
pheA	ilvH_2	ERS852502_00617	ERS852502_01921	P-protein.	Acetolactate synthase isozyme 3 small subunit.	0.631
pheA	tdcB	ERS852502_00617	ERS852502_00315	P-protein.	L-threonine dehydratase catabolic TdcB.	0.401
pheA	thrA	ERS852502_00617	ERS852502_01743	P-protein.	Aspartokinase I/homoserine dehydrogenase I; Belongs to the aspartokinase family.	0.607
sdhB	hom_1	ERS852502_00864	ERS852502_01199	L-serine dehydratase%2C beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Homoserine dehydrogenase.	0.841