(3 nodes) Sigma-70 region 3 network (Ruminococcus torques)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sigF_1	Stage II sporulation protein AC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (260 aa)
	sigA_1	Sigma-A; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (280 aa)
	sigA_2	Sigma-A; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (373 aa)