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guaB guaB purC purC purF purF purB purB nudF nudF pyk pyk purL purL CUQ81864.1 CUQ81864.1 purH purH nrdD nrdD prs_1 prs_1 gmk_1 gmk_1 prs_2 prs_2 hpt hpt relA relA guaD guaD arcC1_1 arcC1_1 CUQ86364.1 CUQ86364.1 ywaC_1 ywaC_1 adk adk hcrA_1 hcrA_1 cutM cutM yfkN_1 yfkN_1 purA purA rdgB rdgB xpt xpt purD purD purN purN purM purM purE purE arcC1_2 arcC1_2 pgcA pgcA ywaC_2 ywaC_2 gmk_3 gmk_3 punA punA deoB deoB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (484 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (291 aa)
purFAmidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (478 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa)
nudFADP-ribose pyrophosphatase. (179 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
purLPhosphoribosylformylglycinamidine synthase. (1251 aa)
CUQ81864.1IMP cyclohydrolase. (237 aa)
purHBifunctional purine biosynthesis protein PurH. (392 aa)
nrdDAnaerobic ribonucleoside-triphosphate reductase. (719 aa)
prs_1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (392 aa)
gmk_1Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (211 aa)
prs_2Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (394 aa)
hptHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (767 aa)
guaDGuanine deaminase. (424 aa)
arcC1_1Carbamate kinase 1; Belongs to the carbamate kinase family. (314 aa)
CUQ86364.1Uncharacterized protein conserved in bacteria. (161 aa)
ywaC_1GTP pyrophosphokinase ywaC. (258 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
hcrA_14-hydroxybenzoyl-CoA reductase subunit alpha. (769 aa)
cutMCarbon monoxide dehydrogenase medium chain. (295 aa)
yfkN_1Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. (649 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (426 aa)
rdgBdITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (204 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (197 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (208 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (341 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (170 aa)
arcC1_2Carbamate kinase 1; Belongs to the carbamate kinase family. (309 aa)
pgcAPhosphoglucomutase. (560 aa)
ywaC_2GTP pyrophosphokinase ywaC. (262 aa)
gmk_3Guanylate kinase. (194 aa)
punAPurine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (396 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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