(10 nodes) Arginine and proline metabolism network (Ruminococcus torques)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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gene neighborhood

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Your Input:
	speA_1	Arginine decarboxylase. (488 aa)
	speE	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (284 aa)
	speB	Agmatinase; Belongs to the arginase family. (285 aa)
	lysA_1	Diaminopimelate decarboxylase. (405 aa)
	aspC	Aspartate aminotransferase. (395 aa)
	crnA	Creatinine amidohydrolase. (247 aa)
	proB	Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (265 aa)
	proA_1	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa)
	proC	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa)
	speA_2	Arginine decarboxylase. (478 aa)

Your Current Organism:

Ruminococcus torques

NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
lysA_1	speA_1	ERS852502_00029	ERS852502_00025	Diaminopimelate decarboxylase.	Arginine decarboxylase.	0.776
lysA_1	speB	ERS852502_00029	ERS852502_00027	Diaminopimelate decarboxylase.	Agmatinase; Belongs to the arginase family.	0.693
lysA_1	speE	ERS852502_00029	ERS852502_00026	Diaminopimelate decarboxylase.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.	0.971
proA_1	proB	ERS852502_02125	ERS852502_01276	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.999
proA_1	proC	ERS852502_02125	ERS852502_02330	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.791
proB	proA_1	ERS852502_01276	ERS852502_02125	Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.999
proB	proC	ERS852502_01276	ERS852502_02330	Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.749
proC	proA_1	ERS852502_02330	ERS852502_02125	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.791
proC	proB	ERS852502_02330	ERS852502_01276	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.749
speA_1	lysA_1	ERS852502_00025	ERS852502_00029	Arginine decarboxylase.	Diaminopimelate decarboxylase.	0.776
speA_1	speA_2	ERS852502_00025	ERS852502_02803	Arginine decarboxylase.	Arginine decarboxylase.	0.922
speA_1	speB	ERS852502_00025	ERS852502_00027	Arginine decarboxylase.	Agmatinase; Belongs to the arginase family.	0.995
speA_1	speE	ERS852502_00025	ERS852502_00026	Arginine decarboxylase.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.	0.980
speA_2	speA_1	ERS852502_02803	ERS852502_00025	Arginine decarboxylase.	Arginine decarboxylase.	0.922
speA_2	speB	ERS852502_02803	ERS852502_00027	Arginine decarboxylase.	Agmatinase; Belongs to the arginase family.	0.944
speA_2	speE	ERS852502_02803	ERS852502_00026	Arginine decarboxylase.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.	0.426
speB	lysA_1	ERS852502_00027	ERS852502_00029	Agmatinase; Belongs to the arginase family.	Diaminopimelate decarboxylase.	0.693
speB	speA_1	ERS852502_00027	ERS852502_00025	Agmatinase; Belongs to the arginase family.	Arginine decarboxylase.	0.995
speB	speA_2	ERS852502_00027	ERS852502_02803	Agmatinase; Belongs to the arginase family.	Arginine decarboxylase.	0.944
speB	speE	ERS852502_00027	ERS852502_00026	Agmatinase; Belongs to the arginase family.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.	0.995