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rhaD rhaD pflB pflB gltB gltB gltD_2 gltD_2 gltX gltX gap gap pgk pgk tpiA tpiA gpmI gpmI pyk pyk lysA_2 lysA_2 pta pta ackA ackA glyA glyA nifH1_1 nifH1_1 nifH1_2 nifH1_2 asd2 asd2 thrC thrC pckA pckA argD argD ltaE ltaE eno_1 eno_1 mro mro prs_1 prs_1 CUQ83124.1 CUQ83124.1 fumB fumB ttdA_1 ttdA_1 dxs_1 dxs_1 tktA tktA tal tal pfkA_1 pfkA_1 prpC_1 prpC_1 dmdA_1 dmdA_1 prs_2 prs_2 dapE_1 dapE_1 glnA_1 glnA_1 fba_1 fba_1 hom_1 hom_1 arcC1_1 arcC1_1 glcK glcK dapB dapB fbp fbp atoA atoA ulaF ulaF fucA fucA csdB csdB rhaA rhaA rhaB_1 rhaB_1 adhE_2 adhE_2 accC accC accB accB rhaB_2 rhaB_2 fucI fucI porA porA rpe rpe hcrA_1 hcrA_1 cutM cutM fhs fhs folD folD gltD_4 gltD_4 mgsA_2 mgsA_2 thrA thrA gcdB gcdB gcdC gcdC icd icd serA_1 serA_1 serC serC pfp pfp lysC lysC gdhA gdhA metF metF dxs_2 dxs_2 nrnA_1 nrnA_1 pgi pgi cysE cysE dkgA dkgA dapA_1 dapA_1 ppdK ppdK acyP acyP rpiB rpiB gltD_5 gltD_5 dapA_2 dapA_2 arcC1_2 arcC1_2 glnA_2 glnA_2 dapF dapF CUQ91595.1 CUQ91595.1 pgcA pgcA CUQ91742.1 CUQ91742.1 CUQ92015.1 CUQ92015.1 prpC_2 prpC_2 fucO fucO CUQ92546.1 CUQ92546.1 fruA fruA fba_2 fba_2 scoA scoA fadB2 fadB2 thlA thlA pfkA_2 pfkA_2 frdB frdB nadB_2 nadB_2 cysK cysK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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rhaDRhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (277 aa)
pflBFormate acetyltransferase. (750 aa)
gltBFerredoxin-dependent glutamate synthase 1. (1507 aa)
gltD_2Glutamate synthase [NADPH] small chain. (499 aa)
gltXGlutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (485 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
gpmI2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (512 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
lysA_2Diaminopimelate decarboxylase. (423 aa)
ptaPhosphate acetyltransferase. (331 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
glyAPyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
nifH1_1Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family. (255 aa)
nifH1_2Nitrogenase iron protein 1; Belongs to the NifH/BchL/ChlL family. (258 aa)
asd2Aspartate-semialdehyde dehydrogenase 2; Belongs to the aspartate-semialdehyde dehydrogenase family. (361 aa)
thrCThreonine synthase. (495 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa)
ltaELow specificity L-threonine aldolase. (341 aa)
eno_1Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
mroAldose 1-epimerase precursor; Converts alpha-aldose to the beta-anomer. (355 aa)
prs_1Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (392 aa)
CUQ83124.14-carboxymuconolactone decarboxylase. (255 aa)
fumBFumarate hydratase class I%2C anaerobic. (187 aa)
ttdA_1L(+)-tartrate dehydratase subunit alpha. (281 aa)
dxs_11-deoxy-D-xylulose-5-phosphate synthase. (313 aa)
tktATransketolase 1. (278 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
pfkA_16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (359 aa)
prpC_12-methylcitrate synthase; Belongs to the citrate synthase family. (456 aa)
dmdA_12%2C3-dimethylmalate dehydratase large subunit. (756 aa)
prs_2Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (394 aa)
dapE_1Probable succinyl-diaminopimelate desuccinylase. (387 aa)
glnA_1Glutamine synthetase. (704 aa)
fba_1Fructose-bisphosphate aldolase. (287 aa)
hom_1Homoserine dehydrogenase. (425 aa)
arcC1_1Carbamate kinase 1; Belongs to the carbamate kinase family. (314 aa)
glcKGlucokinase. (311 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa)
fbpFructose-1%2C6-bisphosphatase class 3. (651 aa)
atoAAcetate CoA-transferase subunit beta; Belongs to the 3-oxoacid CoA-transferase family. (503 aa)
ulaFL-ribulose-5-phosphate 4-epimerase UlaF. (234 aa)
fucAL-fuculose phosphate aldolase. (270 aa)
csdB4-hydroxyphenylacetate decarboxylase large subunit. (843 aa)
rhaAL-rhamnose isomerase; Belongs to the rhamnose isomerase family. (417 aa)
rhaB_1Rhamnulokinase. (467 aa)
adhE_2Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (879 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (163 aa)
rhaB_2Rhamnulokinase. (488 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (598 aa)
porAPyruvate synthase subunit porA. (1190 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
hcrA_14-hydroxybenzoyl-CoA reductase subunit alpha. (769 aa)
cutMCarbon monoxide dehydrogenase medium chain. (295 aa)
fhsFormate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
folDBifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (279 aa)
gltD_4Glutamate synthase [NADPH] small chain. (462 aa)
mgsA_2Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (131 aa)
thrAAspartokinase I/homoserine dehydrogenase I; Belongs to the aspartokinase family. (439 aa)
gcdBGlutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (383 aa)
gcdCGlutaconyl-CoA decarboxylase subunit gamma. (122 aa)
icdIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (398 aa)
serA_1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (387 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)
pfpPyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (417 aa)
lysCAspartokinase 2; Belongs to the aspartokinase family. (400 aa)
gdhANADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa)
metF5%2C10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (289 aa)
dxs_21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (625 aa)
nrnA_1Bifunctional oligoribonuclease and PAP phosphatase nrnA. (325 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (526 aa)
cysESerine acetyltransferase. (231 aa)
dkgA2%2C5-diketo-D-gluconic acid reductase A. (334 aa)
dapA_1Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa)
ppdKPyruvate%2C phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (876 aa)
acyPAcylphosphatase. (93 aa)
rpiBRibose-5-phosphate isomerase B. (147 aa)
gltD_5Glutamate synthase [NADPH] small chain. (408 aa)
dapA_2Dihydrodipicolinate synthase; Belongs to the DapA family. (295 aa)
arcC1_2Carbamate kinase 1; Belongs to the carbamate kinase family. (309 aa)
glnA_2Glutamine synthetase. (444 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (276 aa)
CUQ91595.1Putative dipeptidase SA1572. (452 aa)
pgcAPhosphoglucomutase. (560 aa)
CUQ91742.1Phosphoserine phosphatase. (200 aa)
CUQ92015.1succinyl-CoA synthetase subunit alpha. (469 aa)
prpC_22-methylcitrate synthase; Belongs to the citrate synthase family. (459 aa)
fucOLactaldehyde reductase. (381 aa)
CUQ92546.1Putative 2-hydroxyacid dehydrogenase HI_1556; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
fruAEIIBC-Fru. (360 aa)
fba_2Fructose-bisphosphate aldolase. (294 aa)
scoASuccinyl-CoA:3-ketoacid-coenzyme A transferase subunit A; Belongs to the 3-oxoacid CoA-transferase family. (525 aa)
fadB23-hydroxybutyryl-CoA dehydrogenase. (292 aa)
thlAAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
pfkA_26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (339 aa)
frdBFumarate reductase iron-sulfur subunit. (225 aa)
nadB_2L-aspartate oxidase. (523 aa)
cysKCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
Your Current Organism:
Ruminococcus torques
NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques
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