(16 nodes) Homologous recombination network (Ruminococcus torques)

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Your Input:
	recA	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (379 aa)
	polA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (871 aa)
	CUQ82494.1	DNA polymerase III subunit delta. (345 aa)
	recR	Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)
	dnaX_1	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (530 aa)
	recF	DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (363 aa)
	dnaN	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (369 aa)
	polC_2	DNA polymerase III polC-type. (231 aa)
	recJ	Single-stranded-DNA-specific exonuclease recJ. (574 aa)
	ssb_2	Helix-destabilizing protein. (132 aa)
	recG	ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (686 aa)
	ruvB	Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (332 aa)
	ruvA	Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (202 aa)
	dnaE	DNA polymerase III subunit alpha. (1157 aa)
	ssbB	Single-stranded DNA-binding protein ssbB. (148 aa)
	dnaX_2	DNA polymerase III subunit tau. (331 aa)

Your Current Organism:

Ruminococcus torques

NCBI taxonomy Id: 33039
Other names: ATCC 27756, [. torques, [Ruminococcus] torques

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUQ82494.1	dnaE	ERS852502_00526	ERS852502_02681	DNA polymerase III subunit delta.	DNA polymerase III subunit alpha.	0.992
CUQ82494.1	dnaN	ERS852502_00526	ERS852502_00775	DNA polymerase III subunit delta.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.994
CUQ82494.1	dnaX_1	ERS852502_00526	ERS852502_00731	DNA polymerase III subunit delta.	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.988
CUQ82494.1	dnaX_2	ERS852502_00526	ERS852502_02801	DNA polymerase III subunit delta.	DNA polymerase III subunit tau.	0.987
CUQ82494.1	polA	ERS852502_00526	ERS852502_00299	DNA polymerase III subunit delta.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.639
CUQ82494.1	polC_2	ERS852502_00526	ERS852502_00888	DNA polymerase III subunit delta.	DNA polymerase III polC-type.	0.916
dnaE	CUQ82494.1	ERS852502_02681	ERS852502_00526	DNA polymerase III subunit alpha.	DNA polymerase III subunit delta.	0.992
dnaE	dnaN	ERS852502_02681	ERS852502_00775	DNA polymerase III subunit alpha.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.993
dnaE	dnaX_1	ERS852502_02681	ERS852502_00731	DNA polymerase III subunit alpha.	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.988
dnaE	dnaX_2	ERS852502_02681	ERS852502_02801	DNA polymerase III subunit alpha.	DNA polymerase III subunit tau.	0.987
dnaE	polA	ERS852502_02681	ERS852502_00299	DNA polymerase III subunit alpha.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.729
dnaE	polC_2	ERS852502_02681	ERS852502_00888	DNA polymerase III subunit alpha.	DNA polymerase III polC-type.	0.916
dnaE	recA	ERS852502_02681	ERS852502_00271	DNA polymerase III subunit alpha.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.488
dnaE	recR	ERS852502_02681	ERS852502_00729	DNA polymerase III subunit alpha.	Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.	0.494
dnaE	ruvA	ERS852502_02681	ERS852502_01792	DNA polymerase III subunit alpha.	Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.	0.448
dnaE	ssbB	ERS852502_02681	ERS852502_02718	DNA polymerase III subunit alpha.	Single-stranded DNA-binding protein ssbB.	0.721
dnaE	ssb_2	ERS852502_02681	ERS852502_01395	DNA polymerase III subunit alpha.	Helix-destabilizing protein.	0.721
dnaN	CUQ82494.1	ERS852502_00775	ERS852502_00526	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit delta.	0.994
dnaN	dnaE	ERS852502_00775	ERS852502_02681	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit alpha.	0.993
dnaN	dnaX_1	ERS852502_00775	ERS852502_00731	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.992