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CoaBC CoaBC MazG MazG OAG91942.1 OAG91942.1 Alh-9 Alh-9 OAG91351.1 OAG91351.1 ilvC ilvC ilvH ilvH IlvI IlvI panB panB PanC PanC PanD PanD coaD coaD ilvD ilvD AruI AruI CoaE CoaE PanE PanE OAG90439.1 OAG90439.1 OAG84321.1 OAG84321.1 Ald Ald IlvE IlvE coaX coaX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CoaBCPhosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
MazGNucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
OAG91942.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (505 aa)
Alh-9Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (496 aa)
OAG91351.12-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
ilvHAcetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
IlvIAcetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (266 aa)
PanCPantoate--beta-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
PanDAspartate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (615 aa)
AruIHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
CoaEdephospho-CoA kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
PanE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (306 aa)
OAG90439.1ACP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
OAG84321.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (318 aa)
AldAldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
IlvEBranched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (249 aa)
Your Current Organism:
Pseudomonas viridiflava
NCBI taxonomy Id: 33069
Other names: ATCC 13223, CECT 458, CFBP 2107, CIP 106699, DSM 11124, DSM 6694, ICMP 2848, LMG 2352, LMG:2352, NCPPB 635, NRRL B-895, P. viridiflava, Phytomonas viridiflava, Pseudomonas sp. 286, Pseudomonas syringae group genomosp. 6
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