STRINGSTRING
hemF hemF ubiD ubiD AKO51445.1 AKO51445.1 AKO51446.1 AKO51446.1 AKO51447.1 AKO51447.1 hemC hemC AKO51449.1 AKO51449.1 AKO51450.1 AKO51450.1 AKO51451.1 AKO51451.1 lysA lysA dapF dapF AKO51454.1 AKO51454.1 xerC xerC AKO51456.1 AKO51456.1 hemL hemL AKO51524.1 AKO51524.1 hemE hemE ubiX ubiX hemA hemA AKO54235.1 AKO54235.1 ubiG ubiG AKO52317.1 AKO52317.1 hemH hemH AKO54397.1 AKO54397.1 ubiE ubiE AKO53787.1 AKO53787.1 ubiB ubiB tatA tatA tatB tatB tatC tatC AKO53794.1 AKO53794.1 AKO53796.1 AKO53796.1 AKO53797.1 AKO53797.1 AKO53884.1 AKO53884.1 ubiC ubiC ubiA ubiA AKO53911.1 AKO53911.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (306 aa)
ubiD3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (503 aa)
AKO51445.1Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AKO51446.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AKO51447.1Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (268 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa)
AKO51449.1Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AKO51450.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AKO51451.1Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (61 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (416 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (328 aa)
AKO51454.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
xerCRecombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (324 aa)
AKO51456.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AKO51524.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (355 aa)
ubiXAromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (225 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (429 aa)
AKO54235.1Conjugal transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the COQ7 family. (186 aa)
ubiG3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (250 aa)
AKO52317.1Glutamate-1-semialdehyde 2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (579 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (371 aa)
AKO54397.1Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (503 aa)
ubiEUbiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (263 aa)
AKO53787.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
ubiBUbiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (547 aa)
tatAPreprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (80 aa)
tatBPreprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (155 aa)
tatCTwin-arginine protein translocation system subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (262 aa)
AKO53794.116S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (239 aa)
AKO53796.12-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
AKO53797.12-octaprenyl-6-methoxyphenyl hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AKO53884.1Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (329 aa)
ubiCChorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (201 aa)
ubiA4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (295 aa)
AKO53911.1Ubiquinone biosynthesis protein UbiH; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
Your Current Organism:
Marinobacter psychrophilus
NCBI taxonomy Id: 330734
Other names: CGMCC 1.6499, JCM 14643, M. psychrophilus, Marinobacter psychrophilus Zhang et al. 2008, Marinobacter sp. BSi20041, strain 20041
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.