59 items (Sulfolobus acidocaldarius DSM 639)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	etfB	Electron transfer flavoprotein; Could be both subunits. (243 aa)
	etfA	Electron transfer flavoprotein. (281 aa)
	Saci_0292	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting. (407 aa)
	Saci_0293	Ferredoxin-like protein. (89 aa)
	Saci_0315	Electron transfer flavoprotein; Looks like a hybrid protein, since it contains both the alpha and the beta domain. (609 aa)
	Saci_0316	FixC. (394 aa)
	Saci_0317	Ferredoxin-like protein. (96 aa)
	Saci_0963	acetyl-CoA acetyltransferase. (392 aa)
	Saci_1033	acyl-CoA dehydrogenase. (399 aa)
	ivd	isovaleryl-CoA dehydrogenase. (362 aa)
	Saci_1070	Conserved Prokaryal protein. (145 aa)
	Saci_1071	Conserved protein; acyl-CoA dehydrogenase, C-terminal domain. (267 aa)
	Saci_1078	3-hydroxybutyryl-CoA dehydrogenase; Contains an archaeal insert (ca 281 to 300 AA); similar to sp:P52041. (396 aa)
	Saci_1085	Conserved Prokaryal protein. (167 aa)
	gdh	Glucose 1-dehydrogenase. (252 aa)
	acd	acyl-CoA dehydrogenase. (373 aa)
	Saci_1109	3-hydroxybutyryl-CoA dehydrogenase; Looks like fusion protein; sp:P52046, sp:P520 41; Belongs to the enoyl-CoA hydratase/isomerase family. (663 aa)
	Saci_1113	Matching Pfam: acyl-CoA dehydrogenase, C-terminal domaim. (302 aa)
	Saci_1114	Thiolase. (395 aa)
	Saci_1120	Conserved Archaeal protein. (175 aa)
	Saci_1121	acetyl-CoA thiolase. (395 aa)
	Saci_1134	Hypothetical protein; Similar to 3-hydroxybutyryl-CoA dehydrogenase (N-term) and 3-hydroxybutyryl-CoA dehydratase (C-term); Belongs to the enoyl-CoA hydratase/isomerase family. (662 aa)
	Saci_1359	3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (411 aa)
	Saci_1360	Conserved Archaeal protein. (137 aa)
	acaB1	acetyl-CoA acetyltransferases. (364 aa)
	Saci_1362	DNA/RNA binding protein Alba; Belongs to the thiolase-like superfamily. UPF0219 family. (348 aa)
	acd-2	Multicopy acyl-CoA dehydrogenase. (390 aa)
	Saci_1728	Nonspecific lipid-transfer protein. (376 aa)
	Saci_1729	Hypothetical protein. (89 aa)
	Saci_1758	Conserved Archaeal protein. (115 aa)
	Saci_1759	acetyl-CoA acetyltransferase. (382 aa)
	crt	3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
	Saci_1778	acyl-CoA dehydrogenase; Similar to fragment of transposase ISC1225 from Sulfolobus solfataricus. (557 aa)
	alkK	medium-chain-fatty-acid-CoA ligase. (513 aa)
	Saci_1965	Short chain dehydrogenase. (244 aa)
	fadD	long-chain-fatty-acid-CoA ligase. (511 aa)
	Saci_1967	Mandelate racemase/muconate lactonizing enzyme. (372 aa)
	Saci_1968	Conserved acetyl-CoA acetyltransferase. (386 aa)
	Saci_1969	Conserved protein. (114 aa)
	Saci_1970	Conserved protein; Identification based on homology with Sulfolobus solfataricus and Sulfolobus tokodaii; upstream TATA box was found. (80 aa)
	Saci_2063	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa)
	Saci_2207	4-coumarate-CoA ligase 1. (495 aa)
	Saci_2208	3-hydroxybutyryl-CoA dehydrogenase; Split in two in many organisms. (657 aa)
	Saci_2209	acetyl-CoA thiolase. (395 aa)
	Saci_2210	Conserved Archaeal protein. (180 aa)
	Saci_2217	acyl-CoA dehydrogenase. (399 aa)
	Saci_2218	Conserved 3-hydroxybutyryl-CoA. (639 aa)
	iorB	Indolepyruvate ferredoxin oxidoreductase beta. (188 aa)
	iorA	Indolepyruvate ferredoxin oxidoreductase alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (611 aa)
	Saci_2230	Conserved protein. (144 aa)
	Saci_2231	Conserved Archaeal protein. (165 aa)
	Saci_2232	Conserved Archaeal acetyl-CoA acetyltransferase. (392 aa)
	Saci_2233	acetyl-CoA C-acetyltransferase. (382 aa)
	acd-3	isovaleryl-CoA dehydrogenase. (374 aa)
	paaF-2	enoyl-CoA hydratase/isomerase. (247 aa)
	paaF-3	enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
	Saci_2287	Pyridine nucleotide-disulphide oxidoreductase. (423 aa)
	Saci_2288	Nonspecific lipid-transfer protein. (386 aa)
	Saci_2359	Conserved Archaeal HTH-domain protein. (232 aa)

Your Current Organism:

Sulfolobus acidocaldarius DSM 639

NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Saci_0292	Saci_0293	Saci_0292	Saci_0293	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	Ferredoxin-like protein.	0.905
Saci_0292	Saci_0315	Saci_0292	Saci_0315	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	Electron transfer flavoprotein; Looks like a hybrid protein, since it contains both the alpha and the beta domain.	0.639
Saci_0292	Saci_0317	Saci_0292	Saci_0317	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	Ferredoxin-like protein.	0.886
Saci_0292	etfA	Saci_0292	Saci_0291	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	Electron transfer flavoprotein.	0.908
Saci_0292	etfB	Saci_0292	Saci_0290	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	Electron transfer flavoprotein; Could be both subunits.	0.946
Saci_0293	Saci_0292	Saci_0293	Saci_0292	Ferredoxin-like protein.	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	0.905
Saci_0293	Saci_0315	Saci_0293	Saci_0315	Ferredoxin-like protein.	Electron transfer flavoprotein; Looks like a hybrid protein, since it contains both the alpha and the beta domain.	0.950
Saci_0293	Saci_0316	Saci_0293	Saci_0316	Ferredoxin-like protein.	FixC.	0.861
Saci_0293	Saci_1033	Saci_0293	Saci_1033	Ferredoxin-like protein.	acyl-CoA dehydrogenase.	0.497
Saci_0293	Saci_1071	Saci_0293	Saci_1071	Ferredoxin-like protein.	Conserved protein; acyl-CoA dehydrogenase, C-terminal domain.	0.497
Saci_0293	Saci_1113	Saci_0293	Saci_1113	Ferredoxin-like protein.	Matching Pfam: acyl-CoA dehydrogenase, C-terminal domaim.	0.497
Saci_0293	Saci_1778	Saci_0293	Saci_1778	Ferredoxin-like protein.	acyl-CoA dehydrogenase; Similar to fragment of transposase ISC1225 from Sulfolobus solfataricus.	0.497
Saci_0293	Saci_2217	Saci_0293	Saci_2217	Ferredoxin-like protein.	acyl-CoA dehydrogenase.	0.497
Saci_0293	acd	Saci_0293	Saci_1108	Ferredoxin-like protein.	acyl-CoA dehydrogenase.	0.497
Saci_0293	acd-2	Saci_0293	Saci_1713	Ferredoxin-like protein.	Multicopy acyl-CoA dehydrogenase.	0.497
Saci_0293	acd-3	Saci_0293	Saci_2234	Ferredoxin-like protein.	isovaleryl-CoA dehydrogenase.	0.497
Saci_0293	etfA	Saci_0293	Saci_0291	Ferredoxin-like protein.	Electron transfer flavoprotein.	0.948
Saci_0293	etfB	Saci_0293	Saci_0290	Ferredoxin-like protein.	Electron transfer flavoprotein; Could be both subunits.	0.974
Saci_0293	ivd	Saci_0293	Saci_1069	Ferredoxin-like protein.	isovaleryl-CoA dehydrogenase.	0.497
Saci_0315	Saci_0292	Saci_0315	Saci_0292	Electron transfer flavoprotein; Looks like a hybrid protein, since it contains both the alpha and the beta domain.	Dehydrogenase; Function of the other proteins in this operon makes this conclusion tempting.	0.639