STRINGSTRING
Saci_0016 Saci_0016 Saci_0043 Saci_0043 tpiA tpiA Saci_0141 Saci_0141 Saci_0151 Saci_0151 Saci_0162 Saci_0162 Saci_0166 Saci_0166 Saci_0198 Saci_0198 Saci_0225 Saci_0225 kdgK kdgK cisY cisY pycA pycA rbsK rbsK Saci_0294 Saci_0294 Saci_0410 Saci_0410 Saci_0424 Saci_0424 Saci_0453 Saci_0453 Saci_0553 Saci_0553 fbp fbp Saci_0761 Saci_0761 Saci_0806 Saci_0806 apgM apgM Saci_0885 Saci_0885 Saci_0930 Saci_0930 Saci_1058 Saci_1058 gdh-2 gdh-2 pckG pckG glpK1 glpK1 malA malA Saci_1162 Saci_1162 Saci_1197 Saci_1197 Saci_1198 Saci_1198 Saci_1200 Saci_1200 Saci_1201 Saci_1201 treH2 treH2 Saci_1262 Saci_1262 pgk pgk gap gap eno eno Saci_1417 Saci_1417 Saci_1419 Saci_1419 Saci_1439 Saci_1439 treZ treZ Saci_1518 Saci_1518 Saci_1648 Saci_1648 treH1 treH1 Saci_1827 Saci_1827 bgaS bgaS Saci_1852 Saci_1852 Saci_1938 Saci_1938 Saci_1939 Saci_1939 Saci_1967 Saci_1967 glpK2 glpK2 Saci_2185 Saci_2185 mas mas Saci_2196 Saci_2196 mipS mipS glmS glmS icd icd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Saci_0016Conserved protein. (225 aa)
Saci_0043Phosphoglycerate mutase. (208 aa)
tpiATriosephosphate isomerase P; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (230 aa)
Saci_0141Conserved Archaeal protein. (222 aa)
Saci_0151Bifunctional phosphoglucose isomerase/phosphomannose isomerase; Involved in the synthesis of UDP-N-acetylgalactosamine (UDP- GalNAc). Catalyzes the conversion of glucosamine-6-phosphate (GlcN-6-P) to galactosamine-6-phosphate (GalN-6-P). Belongs to the PGI/PMI family. (306 aa)
Saci_0162Dihydrodipicolinate synthetase; Two copies in each of the Sulfolobus genomes. (285 aa)
Saci_0166Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (521 aa)
Saci_0198Conserved protein. (632 aa)
Saci_02252-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate aldolase; Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto- 3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2- keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3- deoxygalactonate (KDGal); Belongs to the DapA family. KDPG aldolase subfamily. (288 aa)
kdgK2-keto-3-deoxygluconate kinase. (311 aa)
cisYCitrate synthase. (328 aa)
pycAPyruvate carboxylase subunit A. (510 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (288 aa)
Saci_0294Glycosyl transferase. (493 aa)
Saci_0410Alcohol dehydrogenase. (339 aa)
Saci_0424Oxidoreductase. (299 aa)
Saci_0453Conserved Archaeal GtrA-like protein. (143 aa)
Saci_0553Carbohydrate kinase. (287 aa)
fbpConserved Archaeal protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (385 aa)
Saci_0761Epimerase. (308 aa)
Saci_0806Phosphoglucomutase/phosphomannomutase; Belongs to the phosphohexose mutase family. (454 aa)
apgM2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (413 aa)
Saci_0885Conserved Prokaryal protein. (395 aa)
Saci_0930Inositol-1-monophosphatase. (267 aa)
Saci_1058Sugar kinase. (504 aa)
gdh-2Glucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. (364 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (604 aa)
glpK1Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (498 aa)
malAAlpha-glucosidase; Sso3051 maltase (MalA) ortholog; Belongs to the glycosyl hydrolase 31 family. (627 aa)
Saci_1162Membrane bound alpha-amylase; Sso1172 alpha-amylase ortholog fam57 Sto1102; alpha-amylase ortholog fam57. (884 aa)
Saci_1197Conserved protein. (610 aa)
Saci_1198O-glycosyl hydrolase. (617 aa)
Saci_1200Sso0988 alpha-amylase ortholog Sto0817 alpha-amylase orthologue. (444 aa)
Saci_1201Glycosyl transferase; Similar to gi:1592105. (566 aa)
treH2Glycosyl hydrolases family 15 protein; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose; Belongs to the glycosyl hydrolase 15 family. (576 aa)
Saci_1262Conserved protein. (327 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase. (343 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (416 aa)
Saci_1417Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
Saci_1419Inositol-1-phosphate synthase. (358 aa)
Saci_1439Amylase. (713 aa)
treZMaltooligosyl trehalose trehalohydrolase. (556 aa)
Saci_1518Conserved Archaeal protein; Catalyzes the dephosphorylation of 2-phosphoglycolate. (227 aa)
Saci_1648Pyruvate kinase; Belongs to the pyruvate kinase family. (441 aa)
treH1Glycosyl hydrolase; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose; Belongs to the glycosyl hydrolase 15 family. (558 aa)
Saci_1827Glycosyl transferase group 1. (401 aa)
bgaSBeta-galactosidase; Belongs to the glycosyl hydrolase 1 family. (491 aa)
Saci_1852Hypothetical protein; Similar to gi:15899268. (311 aa)
Saci_1938Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa)
Saci_1939Conserved protein. (292 aa)
Saci_1967Mandelate racemase/muconate lactonizing enzyme. (372 aa)
glpK2Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa)
Saci_2185Conserved Archaeal protein. (262 aa)
masMalate synthase. (824 aa)
Saci_2196Mandelate racemase. (372 aa)
mipSMyo-inositol-1-phosphate synthase. (345 aa)
glmSGlucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (590 aa)
icdIsocitrate dehydrogenase. (411 aa)
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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