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rpl1 rpl1 nep1 nep1 rps13 rps13 rps4 rps4 rps11 rps11 rpl15 rpl15 rps5 rps5 rpl18 rpl18 rpl19e rpl19e rpl6 rpl6 rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rpl14 rpl14 rps17 rps17 rps3 rps3 rpl22 rpl22 rps19 rps19 rpl2 rpl2 rpl23 rpl23 rpl4 rpl4 rpl3 rpl3 Saci_0607 Saci_0607 rpl37ae rpl37ae rpl37e rpl37e rps7 rps7 rps12 rps12 rpl24e rpl24e rpl44e rpl44e rpl10 rpl10 rpl11 rpl11 rpl18a rpl18a rpl7ae rpl7ae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl150S ribosomal protein L1P; Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA. (178 aa)
nep1Conserved protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (219 aa)
rps1330S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (170 aa)
rps430S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (176 aa)
rps1130S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (132 aa)
rpl1550S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rps530S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (214 aa)
rpl1850S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (197 aa)
rpl19e50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa)
rpl650S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (186 aa)
rps830S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
rps1430S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (63 aa)
rpl550S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (178 aa)
rps4e30S ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family. (244 aa)
rpl2450S ribosomal protein L24AB; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (134 aa)
rpl1450S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (138 aa)
rps1730S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (114 aa)
rps330S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (231 aa)
rpl2250S ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (156 aa)
rps1930S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rpl250S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
rpl2350S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa)
rpl450S ribosomal protein L4E; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (266 aa)
rpl350S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (342 aa)
Saci_0607Conserved brix domain protein; Probably involved in the biogenesis of the ribosome. (199 aa)
rpl37ae50S ribosomal protein L37AE; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (70 aa)
rpl37e50S ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (61 aa)
rps730S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (195 aa)
rps1230S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl24e50S ribosomal protein L24E; Binds to the 23S rRNA. (62 aa)
rpl44e50S ribosomal protein L44E; Binds to the 23S rRNA. (95 aa)
rpl1050S ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. (335 aa)
rpl1150S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (170 aa)
rpl18a50S ribosomal protein LX. (86 aa)
rpl7ae50S ribosomal protein L7AE; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (126 aa)
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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