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| | hpaA | 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component. (490 aa) |
| | Saci_2293 | 4-hydroxyphenylacetate degradation bifunctionali somerase/decarboxylase. (280 aa) |
| | Saci_2291 | Conserved Archaeal protein. (127 aa) |
| | paaK | Phenylacetate-coenzyme A ligase. (428 aa) |
| | Saci_2288 | Nonspecific lipid-transfer protein. (386 aa) |
| | paaF-3 | enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa) |
| | paaF-2 | enoyl-CoA hydratase/isomerase. (247 aa) |
| | cutB | Carbon monoxide dehydrogenase medium chain; Component of the glyceraldehyde dehydrogenase which is involved the nonphosphorylated Entner-Doudoroff pathway. Catalyzes the oxidation of D-glyceraldehyde to yield glycerate. When the artificial electron acceptor 2,6-dichlorophenol-indophenol (Cl2Ind) is used, the enzyme shows a broad substrate range (glyceraldehyde-3-phosphate, formaldehyde, acetaldehyde, propionaldehyde and isobutyraldehyde), but is most active with D-glyceraldehyde. It is not known which acceptor is utilized in vivo. (281 aa) |
| | Saci_2246 | Carbon monoxide dehydrogenase. (459 aa) |
| | acd-3 | isovaleryl-CoA dehydrogenase. (374 aa) |
| | Saci_2233 | acetyl-CoA C-acetyltransferase. (382 aa) |
| | Saci_2232 | Conserved Archaeal acetyl-CoA acetyltransferase. (392 aa) |
| | Saci_2231 | Conserved Archaeal protein. (165 aa) |
| | Saci_2230 | Conserved protein. (144 aa) |
| | Saci_2218 | Conserved 3-hydroxybutyryl-CoA. (639 aa) |
| | Saci_2217 | acyl-CoA dehydrogenase. (399 aa) |
| | Saci_2210 | Conserved Archaeal protein. (180 aa) |
| | Saci_2209 | acetyl-CoA thiolase. (395 aa) |
| | Saci_2208 | 3-hydroxybutyryl-CoA dehydrogenase; Split in two in many organisms. (657 aa) |
| | Saci_2196 | Mandelate racemase. (372 aa) |
| | Saci_2150 | Conserved Archaeal protein. (305 aa) |
| | Saci_2149 | Fumarylacetoacetate (FAA) hydrolase. (315 aa) |
| | Saci_2146 | phenylacetyl-CoA ligase; Conserved in Sulfolobus. (475 aa) |
| | abfD | Gamma-aminobutyrate metabolism dehydratase/isomerase. (505 aa) |
| | Saci_2130 | Oxidoreductase. (264 aa) |
| | Saci_2074 | Conserved HD domain protein. (414 aa) |
| | Saci_2063 | enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (254 aa) |
| | Saci_2056 | Hypothetical protein. (316 aa) |
| | glpK2 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa) |
| | Saci_2012 | Conserved protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (133 aa) |
| | Saci_1969 | Conserved protein. (114 aa) |
| | Saci_1968 | Conserved acetyl-CoA acetyltransferase. (386 aa) |
| | Saci_1967 | Mandelate racemase/muconate lactonizing enzyme. (372 aa) |
| | Saci_1965 | Short chain dehydrogenase. (244 aa) |
| | Saci_1939 | Conserved protein. (292 aa) |
| | Saci_1938 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (478 aa) |
| | Saci_1862 | Conserved Archaeal protein. (97 aa) |
| | Saci_1852 | Hypothetical protein; Similar to gi:15899268. (311 aa) |
| | Saci_1844 | Hypothetical protein. (178 aa) |
| | Saci_1843 | Hypothetical protein. (115 aa) |
| | Saci_1836 | Amidohydrolase. (410 aa) |
| | treH1 | Glycosyl hydrolase; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose; Belongs to the glycosyl hydrolase 15 family. (558 aa) |
| | Saci_1807 | Conserved Archaeal protein. (223 aa) |
| | Saci_1792 | Short chain dehydrogenase. (304 aa) |
| | Saci_1781 | Amidohydrolase. (400 aa) |
| | Saci_1778 | acyl-CoA dehydrogenase; Similar to fragment of transposase ISC1225 from Sulfolobus solfataricus. (557 aa) |
| | crt | 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa) |
| | Saci_1771 | Phenylacetic acid catabolic protein. (256 aa) |
| | Saci_1770 | Phenylacetic acid catabolic protein. (231 aa) |
| | Saci_1767 | Fumarylacetoacetate (FAA) hydrolase. (307 aa) |
| | Saci_1759 | acetyl-CoA acetyltransferase. (382 aa) |
| | Saci_1758 | Conserved Archaeal protein. (115 aa) |
| | Saci_1729 | Hypothetical protein. (89 aa) |
| | Saci_1728 | Nonspecific lipid-transfer protein. (376 aa) |
| | acd-2 | Multicopy acyl-CoA dehydrogenase. (390 aa) |
| | Saci_1648 | Pyruvate kinase; Belongs to the pyruvate kinase family. (441 aa) |
| | paaF | 3-hydroxybutyryl-CoA dehydratase; Several copies; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa) |
| | pdxT | SNO glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (200 aa) |
| | Saci_1517 | Conserved protein. (400 aa) |
| | Saci_1512 | Conserved Archaeal protein; Belongs to the UPF0173 family. (206 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (138 aa) |
| | gcsT | Aminomethyltransferase. (351 aa) |
| | gcvPA | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (447 aa) |
| | gcvP | Glycine dehydrogenase. (505 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (416 aa) |
| | sph1 | S-adenosylmethionine decarboxylase proenzyme 1; Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (130 aa) |
| | acaB1 | acetyl-CoA acetyltransferases. (364 aa) |
| | Saci_1360 | Conserved Archaeal protein. (137 aa) |
| | gap | Glyceraldehyde-3-phosphate dehydrogenase. (343 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa) |
| | Saci_1253 | Conserved Crenarchaeal protein. (264 aa) |
| | treH2 | Glycosyl hydrolases family 15 protein; Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose; Belongs to the glycosyl hydrolase 15 family. (576 aa) |
| | mtaP | 5'-methylthioadenosine phosphorylase. (236 aa) |
| | Saci_1246 | Conserved protein. (398 aa) |
| | Saci_1232 | Short chain dehydrogenase. (255 aa) |
| | Saci_1195 | Endoribonuclease L-PSP. (125 aa) |
| | Saci_1188 | Alkyldihydroxyacetonephosphate synthase. (453 aa) |
| | Saci_1134 | Hypothetical protein; Similar to 3-hydroxybutyryl-CoA dehydrogenase (N-term) and 3-hydroxybutyryl-CoA dehydratase (C-term); Belongs to the enoyl-CoA hydratase/isomerase family. (662 aa) |
| | Saci_1123 | acyl-CoA dehydrogenase. (400 aa) |
| | Saci_1121 | acetyl-CoA thiolase. (395 aa) |
| | Saci_1120 | Conserved Archaeal protein. (175 aa) |
| | glpK1 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (498 aa) |
| | Saci_1114 | Thiolase. (395 aa) |
| | Saci_1113 | Matching Pfam: acyl-CoA dehydrogenase, C-terminal domaim. (302 aa) |
| | Saci_1110 | Conserved protein. (306 aa) |
| | Saci_1109 | 3-hydroxybutyryl-CoA dehydrogenase; Looks like fusion protein; sp:P52046, sp:P520 41; Belongs to the enoyl-CoA hydratase/isomerase family. (663 aa) |
| | acd | acyl-CoA dehydrogenase. (373 aa) |
| | gdh | Glucose 1-dehydrogenase. (252 aa) |
| | Saci_1103 | Hydroxylase. (463 aa) |
| | gdh-2 | Glucose 1-dehydrogenase; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway. (364 aa) |
| | rph | Ribonuclease PH; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (243 aa) |
| | rrp4 | Conserved Archaeal KH domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (249 aa) |
| | psmA | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (242 aa) |
| | pan | Protease regulatory protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S pro [...] (396 aa) |
| | psmB1 | Proteasome protease subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (195 aa) |
| | Saci_0702 | Conserved protein. (192 aa) |
| | Saci_0713 | Threonine dehydratase. (404 aa) |
| | fen | XPG/RAD25 related endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] (331 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (413 aa) |
| | Saci_0849 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa) |
| | Saci_0885 | Conserved Prokaryal protein. (395 aa) |
| | psmB2 | Proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (203 aa) |
| | Saci_0916 | Carbon monoxide dehydrogenase medium chain. (280 aa) |
| | Saci_0930 | Inositol-1-monophosphatase. (267 aa) |
| | Saci_0941 | Conserved thermophile protein; Similar to gi:15920755. (206 aa) |
| | Saci_0954 | Conserved Archaeal protein; Similar to gi:15920742. (177 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (212 aa) |
| | Saci_0963 | acetyl-CoA acetyltransferase. (392 aa) |
| | Saci_1021 | Conserved Crenarchaeal protein. (269 aa) |
| | Saci_1033 | acyl-CoA dehydrogenase. (399 aa) |
| | ivd | isovaleryl-CoA dehydrogenase. (362 aa) |
| | Saci_1071 | Conserved protein; acyl-CoA dehydrogenase, C-terminal domain. (267 aa) |
| | Saci_1078 | 3-hydroxybutyryl-CoA dehydrogenase; Contains an archaeal insert (ca 281 to 300 AA); similar to sp:P52041. (396 aa) |
| | Saci_0037 | Hypothetical protein. (351 aa) |
| | dtdA | Conserved Archaeal protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (237 aa) |
| | Saci_0043 | Phosphoglycerate mutase. (208 aa) |
| | Saci_0062 | methylmalonyl-CoA mutase C-terminal domain/subunit. (140 aa) |
| | pelA | Conserved Archaeal protein; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (342 aa) |
| | tpiA | Triosephosphate isomerase P; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (230 aa) |
| | Saci_0123 | Conserved protein. (198 aa) |
| | gdhA | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (423 aa) |
| | Saci_0158 | Short chain dehydrogenase. (262 aa) |
| | Saci_0166 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (521 aa) |
| | csl4 | Conserved Archaeal protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (180 aa) |
| | glcD | Glycolate oxidase subunit. (458 aa) |
| | Saci_0238 | Short chain dehydrogenase. (251 aa) |
| | Saci_0244 | Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (280 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (288 aa) |
| | Saci_0274 | Conserved protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (203 aa) |
| | dld | D-lactate dehydrogenase. (440 aa) |
| | gcs3 | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (146 aa) |
| | gcs2 | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (149 aa) |
| | Saci_0385 | 3-hydroxyisobutyrate dehydrogenase. (287 aa) |
| | Saci_0410 | Alcohol dehydrogenase. (339 aa) |
| | Saci_0425 | Gamma-glutamyltranspeptidase. (479 aa) |
| | Saci_0427 | Conserved Archaeal protein. (83 aa) |
| | Saci_0458 | DNA/pantothenate metabolism flavoprotein. (409 aa) |
| | Saci_0553 | Carbohydrate kinase. (287 aa) |
| | Saci_2328 | Conserved protein. (273 aa) |
| | rrp42 | Exosome complex exonuclease RRP43-like protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (276 aa) |
