(19 nodes) AMP-dependent synthetase/ligase domain network (Sulfolobus acidocaldarius DSM 639)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Saci_0025	Acetyl-coenzyme A synthetase. (568 aa)
	Saci_0306	Acetyl-coenzyme A synthetase. (665 aa)
	Saci_1054	medium-chain-fatty-acid-CoA ligase. (552 aa)
	acs	acyl-CoA synthetase. (505 aa)
	Saci_1111	medium-chain-fatty-acid-CoA ligase. (550 aa)
	Saci_1122	acyl-CoA synthetase. (537 aa)
	Saci_1126	medium-chain-fatty-acid-CoA ligase. (550 aa)
	Saci_1184	Acetyl-coenzyme A synthetase; acetate-CoA ligase, acyl-activating enzyme. (654 aa)
	Saci_1774	Acetyl-coenzyme A synthetase. (526 aa)
	alkK	medium-chain-fatty-acid-CoA ligase. (513 aa)
	fadD	long-chain-fatty-acid-CoA ligase. (511 aa)
	acs-2	Acetyl-coenzyme A synthetase. (561 aa)
	fadD-2	long-chain-fatty-acid-CoA ligase. (555 aa)
	Saci_2207	4-coumarate-CoA ligase 1. (495 aa)
	Saci_2211	medium-chain-fatty-acid-CoA ligase; Multicopy protein. (555 aa)
	Saci_2225	medium-chain-fatty-acid-CoA ligase. (541 aa)
	Saci_2235	acyl-CoA synthetase. (619 aa)
	paaK	Phenylacetate-coenzyme A ligase. (428 aa)
	acsA	Acetyl-coenzyme A synthetase. (606 aa)

Your Current Organism:

Sulfolobus acidocaldarius DSM 639

NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Saci_0025	Saci_0306	Saci_0025	Saci_0306	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.714
Saci_0025	Saci_1054	Saci_0025	Saci_1054	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.513
Saci_0025	Saci_1111	Saci_0025	Saci_1111	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.513
Saci_0025	Saci_1122	Saci_0025	Saci_1122	Acetyl-coenzyme A synthetase.	acyl-CoA synthetase.	0.513
Saci_0025	Saci_1126	Saci_0025	Saci_1126	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.513
Saci_0025	Saci_1774	Saci_0025	Saci_1774	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.705
Saci_0025	Saci_2207	Saci_0025	Saci_2207	Acetyl-coenzyme A synthetase.	4-coumarate-CoA ligase 1.	0.566
Saci_0025	Saci_2211	Saci_0025	Saci_2211	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase; Multicopy protein.	0.513
Saci_0025	Saci_2225	Saci_0025	Saci_2225	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.513
Saci_0025	Saci_2235	Saci_0025	Saci_2235	Acetyl-coenzyme A synthetase.	acyl-CoA synthetase.	0.708
Saci_0025	acs	Saci_0025	Saci_1084	Acetyl-coenzyme A synthetase.	acyl-CoA synthetase.	0.513
Saci_0025	acs-2	Saci_0025	Saci_2062	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.739
Saci_0025	acsA	Saci_0025	Saci_2298	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.709
Saci_0025	alkK	Saci_0025	Saci_1779	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.535
Saci_0025	fadD	Saci_0025	Saci_1966	Acetyl-coenzyme A synthetase.	long-chain-fatty-acid-CoA ligase.	0.573
Saci_0025	fadD-2	Saci_0025	Saci_2148	Acetyl-coenzyme A synthetase.	long-chain-fatty-acid-CoA ligase.	0.560
Saci_0306	Saci_0025	Saci_0306	Saci_0025	Acetyl-coenzyme A synthetase.	Acetyl-coenzyme A synthetase.	0.714
Saci_0306	Saci_1054	Saci_0306	Saci_1054	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.513
Saci_0306	Saci_1111	Saci_0306	Saci_1111	Acetyl-coenzyme A synthetase.	medium-chain-fatty-acid-CoA ligase.	0.513
Saci_0306	Saci_1122	Saci_0306	Saci_1122	Acetyl-coenzyme A synthetase.	acyl-CoA synthetase.	0.513