(15 nodes) Preribosome, large subunit precursor, and rRNA (cytosine) methyltransferase activity network (Aspergillus fumigatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_2G17060	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
	AFUA_6G04260	Protein MAK16; Belongs to the MAK16 family. (324 aa)
	AFUA_5G01760	Nucleolar RNA methyltransferase (Nop2), putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (751 aa)
	AFUA_7G05460	Uncharacterized protein. (404 aa)
	AFUA_4G06350	Ribosomal biogenesis protein Gar2. (509 aa)
	ytm1	Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (488 aa)
	nop7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
	has1	ATP-dependent RNA helicase has1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA. (622 aa)
	AFUA_1G16330	Ribosome assembly protein Noc2, putative. (788 aa)
	AFUA_1G10990	Ribosomal RNA processing protein, putative. (325 aa)
	AFUA_1G10560	GTP binding protein, putative. (462 aa)
	erb1	Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (795 aa)
	AFUA_5G05930	RNA processing factor 1. (425 aa)
	AFUA_5G12270	rRNA processing protein (Ebp2), putative. (384 aa)
	AFUA_2G17050	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (692 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G10560	AFUA_1G10990	Q4WT48	Q4WT06	GTP binding protein, putative.	Ribosomal RNA processing protein, putative.	0.958
AFUA_1G10560	AFUA_1G16330	Q4WT48	Q4WRH1	GTP binding protein, putative.	Ribosome assembly protein Noc2, putative.	0.997
AFUA_1G10560	AFUA_2G17050	Q4WT48	Q4WZG4	GTP binding protein, putative.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.991
AFUA_1G10560	AFUA_2G17060	Q4WT48	E9QUX5	GTP binding protein, putative.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.985
AFUA_1G10560	AFUA_4G06350	Q4WT48	Q4WNN3	GTP binding protein, putative.	Ribosomal biogenesis protein Gar2.	0.998
AFUA_1G10560	AFUA_5G01760	Q4WT48	Q4WE49	GTP binding protein, putative.	Nucleolar RNA methyltransferase (Nop2), putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.998
AFUA_1G10560	AFUA_5G05930	Q4WT48	Q4WTS5	GTP binding protein, putative.	RNA processing factor 1.	0.985
AFUA_1G10560	AFUA_5G12270	Q4WT48	Q4WVJ0	GTP binding protein, putative.	rRNA processing protein (Ebp2), putative.	0.999
AFUA_1G10560	AFUA_6G04260	Q4WT48	Q4WDC4	GTP binding protein, putative.	Protein MAK16; Belongs to the MAK16 family.	0.978
AFUA_1G10560	AFUA_7G05460	Q4WT48	Q4WGL6	GTP binding protein, putative.	Uncharacterized protein.	0.994
AFUA_1G10560	erb1	Q4WT48	Q4WTI3	GTP binding protein, putative.	Ribosome biogenesis protein erb1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
AFUA_1G10560	has1	Q4WT48	Q4WQM4	GTP binding protein, putative.	ATP-dependent RNA helicase has1; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.	0.996
AFUA_1G10560	nop7	Q4WT48	Q4WP65	GTP binding protein, putative.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
AFUA_1G10560	ytm1	Q4WT48	Q4WP10	GTP binding protein, putative.	Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.996
AFUA_1G10990	AFUA_1G10560	Q4WT06	Q4WT48	Ribosomal RNA processing protein, putative.	GTP binding protein, putative.	0.958
AFUA_1G10990	AFUA_1G16330	Q4WT06	Q4WRH1	Ribosomal RNA processing protein, putative.	Ribosome assembly protein Noc2, putative.	0.972
AFUA_1G10990	AFUA_2G17050	Q4WT06	Q4WZG4	Ribosomal RNA processing protein, putative.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.950
AFUA_1G10990	AFUA_2G17060	Q4WT06	E9QUX5	Ribosomal RNA processing protein, putative.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.968
AFUA_1G10990	AFUA_4G06350	Q4WT06	Q4WNN3	Ribosomal RNA processing protein, putative.	Ribosomal biogenesis protein Gar2.	0.988
AFUA_1G10990	AFUA_5G01760	Q4WT06	Q4WE49	Ribosomal RNA processing protein, putative.	Nucleolar RNA methyltransferase (Nop2), putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.984