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AFUA_5G14315 AFUA_5G14315 AFUA_7G04230 AFUA_7G04230 mcd4 mcd4 rglA rglA AFUA_7G01280 AFUA_7G01280 gpi14 gpi14 AFUA_7G02290 AFUA_7G02290 AFUA_8G02020 AFUA_8G02020 AFUA_8G05410 AFUA_8G05410 AFUA_8G04430 AFUA_8G04430 AFUA_6G04210 AFUA_6G04210 AFUA_6G04240 AFUA_6G04240 AFUA_6G04290 AFUA_6G04290 las21 las21 AFUA_5G01380 AFUA_5G01380 AFUA_5G01810 AFUA_5G01810 AFUA_5G03500 AFUA_5G03500 AFUA_7G04110 AFUA_7G04110 bst1 bst1 AFUA_2G06280 AFUA_2G06280 AFUA_2G05790 AFUA_2G05790 AFUA_2G02570 AFUA_2G02570 AFUA_2G02360 AFUA_2G02360 gpi11 gpi11 AFUA_2G00490 AFUA_2G00490 AFUA_1G06890 AFUA_1G06890 AFUA_1G06560 AFUA_1G06560 AFUA_1G06200 AFUA_1G06200 AFUA_1G05470 AFUA_1G05470 AFUA_1G03810 AFUA_1G03810 AFUA_1G03140 AFUA_1G03140 AFUA_1G03020 AFUA_1G03020 AFUA_6G14180 AFUA_6G14180 AFUA_6G12760 AFUA_6G12760 AFUA_6G12360 AFUA_6G12360 AFUA_6G11240 AFUA_6G11240 AFUA_6G09200 AFUA_6G09200 AFUA_6G09020 AFUA_6G09020 AFUA_6G07180 AFUA_6G07180 alg14 alg14 AFUA_6G06790 AFUA_6G06790 AFUA_4G08200 AFUA_4G08200 AFUA_4G08350 AFUA_4G08350 AFUA_4G08660 AFUA_4G08660 AFUA_4G09060 AFUA_4G09060 gpi10 gpi10 AFUA_4G10070 AFUA_4G10070 gpi18 gpi18 AFUA_4G12900 AFUA_4G12900 alg13 alg13 AFUA_1G17030 AFUA_1G17030 AFUA_1G16950 AFUA_1G16950 AFUA_1G15130 AFUA_1G15130 mns1B mns1B AFUA_1G14140 AFUA_1G14140 AFUA_1G13870 AFUA_1G13870 AFUA_1G09890 AFUA_1G09890 smp3 smp3 AFUA_5G07600 AFUA_5G07600 AFUA_5G08210 AFUA_5G08210 AFUA_5G08580 AFUA_5G08580 AFUA_5G08970 AFUA_5G08970 alg3 alg3 AFUA_5G12550 AFUA_5G12550 AFUA_5G13210 AFUA_5G13210 AFUA_3G07170 AFUA_3G07170 AFUA_3G07700 AFUA_3G07700 AFUA_3G09740 AFUA_3G09740 AFUA_3G09860 AFUA_3G09860 AFUA_3G10400 AFUA_3G10400 AFUA_3G13360 AFUA_3G13360 AFUA_2G16790 AFUA_2G16790 AFUA_2G12410 AFUA_2G12410 AFUA_2G11240 AFUA_2G11240 alg10 alg10 AFUA_2G10930 AFUA_2G10930 AFUA_2G07590 AFUA_2G07590 AFUA_4G12850 AFUA_4G12850 gwt1 gwt1 nmt1 nmt1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
AFUA_5G14315Uncharacterized protein. (370 aa)
AFUA_7G04230Uncharacterized protein. (290 aa)
mcd4GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). (1032 aa)
rglAProbable rhamnogalacturonate lyase A; Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity). (528 aa)
AFUA_7G01280DNA damage response protein RcaA. (704 aa)
gpi14GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity). (425 aa)
AFUA_7G02290alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1080 aa)
AFUA_8G02020Glycosyltransferase, putative. (717 aa)
AFUA_8G05410Extracellular matrix protein, putative. (221 aa)
AFUA_8G04430Oligosaccharyl transferase subunit (Stt3), putative. (743 aa)
AFUA_6G04210Mannosyl-oligosaccharide glucosidase, putative. (822 aa)
AFUA_6G04240PAP2 domain protein. (214 aa)
AFUA_6G04290Phosphoethanolamine N-methyltransferase, putative. (1056 aa)
las21GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity). (767 aa)
AFUA_5G01380CIA30 domain-containing protein. (185 aa)
AFUA_5G01810PIG-P domain-containing protein. (384 aa)
AFUA_5G03500Alpha glucosidase II, alpha subunit, putative; Belongs to the glycosyl hydrolase 31 family. (967 aa)
AFUA_7G04110Protein kinase C substrate, putative. (540 aa)
bst1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1156 aa)
AFUA_2G06280Oligosaccharyl transferase subunit (Gamma), putative. (325 aa)
AFUA_2G05790Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (504 aa)
AFUA_2G02570F-box domain protein. (378 aa)
AFUA_2G02360UDP-glucose:glycoprotein glucosyltransferase, putative. (1487 aa)
gpi11Glycosylphosphatidylinositol anchor biosynthesis protein 11; Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein. (297 aa)
AFUA_2G00490Glycosyl hydrolase, family 31; Belongs to the glycosyl hydrolase 31 family. (173 aa)
AFUA_1G06890Alpha-1,2-mannosyltransferase (Alg11), putative. (560 aa)
AFUA_1G06560Alpha-glucosidase, putative; Belongs to the glycosyl hydrolase 31 family. (848 aa)
AFUA_1G06200Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (332 aa)
AFUA_1G054703-oxo-5-alpha-steroid 4-dehydrogenase, putative. (311 aa)
AFUA_1G03810Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (189 aa)
AFUA_1G03140Glycosyl hydrolase, putative; Belongs to the glycosyl hydrolase 31 family. (654 aa)
AFUA_1G03020Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (79 aa)
AFUA_6G14180Beta-1,4-mannosyltransferase (Alg1), putative. (461 aa)
AFUA_6G12760GPI transamidase component (GAA1), putative. (622 aa)
AFUA_6G12360alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (893 aa)
AFUA_6G11240Uncharacterized protein. (77 aa)
AFUA_6G09200Uncharacterized protein. (266 aa)
AFUA_6G09020GPI transamidase component Gpi16, putative. (600 aa)
AFUA_6G07180GPI transamidase component PIG-S, putative. (618 aa)
alg14UDP-N-acetylglucosamine transferase subunit alg14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit alg13 to the ER (By similarity). (228 aa)
AFUA_6G06790alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (704 aa)
AFUA_4G08200GPI transamidase component PIG-U, putative. (423 aa)
AFUA_4G08350Monosaccharide-P-dolichol utilization protein, putative. (298 aa)
AFUA_4G08660Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (289 aa)
AFUA_4G09060Phosphatidate cytidylyltransferase, putative. (890 aa)
gpi10GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity). (771 aa)
AFUA_4G10070alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (641 aa)
gpi18GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity). (441 aa)
AFUA_4G12900Mannosyltransferase. (575 aa)
alg13UDP-N-acetylglucosamine transferase subunit alg13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity). Belongs to the glycosyltransferase 28 family. (197 aa)
AFUA_1G17030Glycosyl transferase, putative. (477 aa)
AFUA_1G16950Phosphatidylinositol:UDP-GlcNAc transferase subunit PIG-A. (488 aa)
AFUA_1G15130GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (398 aa)
mns1BProbable mannosyl-oligosaccharide alpha-1,2-mannosidase 1B; Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (By similarity). (493 aa)
AFUA_1G14140GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (319 aa)
AFUA_1G13870Mannosyltransferase. (632 aa)
AFUA_1G09890Uncharacterized protein. (81 aa)
smp3GPI mannosyltransferase 4; Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi (By similarity). (547 aa)
AFUA_5G07600Inositol 5-phosphatase, putative. (451 aa)
AFUA_5G08210Dolichyl-phosphate beta-glucosyltransferase, putative. (421 aa)
AFUA_5G08580Alpha-1,6-mannosyltransferase subunit (Och1), putative. (425 aa)
AFUA_5G08970Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (462 aa)
alg3Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol; Belongs to the ALG3 family. (419 aa)
AFUA_5G12550N-acetylglucosaminyl-phosphatidylinositol deacetylase, putative. (303 aa)
AFUA_5G13210Alpha-1,2-mannosyltransferase (Alg2), putative. (470 aa)
AFUA_3G07170Phosphatidylinositol:UDP-GlcNAc transferase PIG-C. (508 aa)
AFUA_3G07700Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (593 aa)
AFUA_3G09740Integral plasma membrane protein, putative. (939 aa)
AFUA_3G09860N-acetylglucosaminyl transferase component Gpi1. (730 aa)
AFUA_3G10400Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (245 aa)
AFUA_3G13360Phosphatidylinositol N-acetylglucosaminyltransferase, putative. (157 aa)
AFUA_2G16790Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (440 aa)
AFUA_2G12410Uncharacterized protein. (1048 aa)
AFUA_2G11240UDP-N-acetyl-glucosamine-1-P transferase Alg7, putative. (468 aa)
alg10Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol; Belongs to the ALG10 glucosyltransferase family. (614 aa)
AFUA_2G10930Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (188 aa)
AFUA_2G07590Beta-1,6-glucan boisynthesis protein (Knh1), putative. (259 aa)
AFUA_4G12850Calnexin homolog; Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Belongs to the calreticulin family. (563 aa)
gwt1GPI-anchored wall transfer protein 1; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (501 aa)
nmt1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (492 aa)
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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