(22 nodes) KEAP1-NFE2L2 pathway, and Ubiquitin-dependent ERAD pathway network (Aspergillus fumigatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AFUA_1G14690	Ubiquitin-protein ligase Sel1/Ubx2, putative. (852 aa)
	AFUA_7G05752	AAA family ATPase, putative. (1009 aa)
	AFUA_2G17110	Cell division control protein Cdc48; Belongs to the AAA ATPase family. (819 aa)
	AFUA_4G04800	AAA family ATPase, putative. (759 aa)
	AFUA_4G04640	Ubiquitin fusion degradation protein (Ufd1), putative. (795 aa)
	AFUA_8G00780	Uncharacterized protein. (932 aa)
	AFUA_8G04840	RING finger protein. (771 aa)
	yos9	Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity). (520 aa)
	AFUA_6G04670	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (249 aa)
	AFUA_5G03610	Cdc48-dependent protein degradation adaptor protein (Shp1), putative. (394 aa)
	AFUA_7G04320	UBX domain protein (Ubx5), putative. (527 aa)
	AFUA_7G06680	AAA family ATPase, putative. (631 aa)
	png1	Protein png1; Belongs to the transglutaminase-like superfamily. PNGase family. (455 aa)
	npl4	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa)
	AFUA_1G02430	Ubiquitin fusion degradation protein Ufd1, putative. (384 aa)
	AFUA_4G06960	UBX domain protein, putative. (306 aa)
	AFUA_4G07340	Ubiquitin fusion degradation protein UfdB, putative. (1088 aa)
	AFUA_4G07430	UBX domain protein, putative. (519 aa)
	AFUA_5G06040	UV excision repair protein (RadW), putative. (376 aa)
	AFUA_5G08370	Polyubiquitin binding protein (Doa1/Ufd3), putative. (790 aa)
	AFUA_3G05550	OTU-like cysteine protease, putative. (340 aa)
	AFUA_2G13880	SH3 domain protein. (840 aa)

Your Current Organism:

Aspergillus fumigatus

NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFUA_1G02430	AFUA_1G14690	Q4WKH7	A4D9K5	Ubiquitin fusion degradation protein Ufd1, putative.	Ubiquitin-protein ligase Sel1/Ubx2, putative.	0.592
AFUA_1G02430	AFUA_2G17110	Q4WKH7	E9QVU7	Ubiquitin fusion degradation protein Ufd1, putative.	Cell division control protein Cdc48; Belongs to the AAA ATPase family.	0.998
AFUA_1G02430	AFUA_3G05550	Q4WKH7	Q4WWE5	Ubiquitin fusion degradation protein Ufd1, putative.	OTU-like cysteine protease, putative.	0.982
AFUA_1G02430	AFUA_4G04640	Q4WKH7	Q4W9K1	Ubiquitin fusion degradation protein Ufd1, putative.	Ubiquitin fusion degradation protein (Ufd1), putative.	0.540
AFUA_1G02430	AFUA_4G04800	Q4WKH7	Q4W9I5	Ubiquitin fusion degradation protein Ufd1, putative.	AAA family ATPase, putative.	0.947
AFUA_1G02430	AFUA_4G06960	Q4WKH7	Q4WNU2	Ubiquitin fusion degradation protein Ufd1, putative.	UBX domain protein, putative.	0.518
AFUA_1G02430	AFUA_4G07340	Q4WKH7	Q4WNY0	Ubiquitin fusion degradation protein Ufd1, putative.	Ubiquitin fusion degradation protein UfdB, putative.	0.977
AFUA_1G02430	AFUA_4G07430	Q4WKH7	Q4WNY9	Ubiquitin fusion degradation protein Ufd1, putative.	UBX domain protein, putative.	0.529
AFUA_1G02430	AFUA_5G03610	Q4WKH7	Q4WEN2	Ubiquitin fusion degradation protein Ufd1, putative.	Cdc48-dependent protein degradation adaptor protein (Shp1), putative.	0.907
AFUA_1G02430	AFUA_5G06040	Q4WKH7	Q4WTT6	Ubiquitin fusion degradation protein Ufd1, putative.	UV excision repair protein (RadW), putative.	0.691
AFUA_1G02430	AFUA_5G08370	Q4WKH7	Q4WUG5	Ubiquitin fusion degradation protein Ufd1, putative.	Polyubiquitin binding protein (Doa1/Ufd3), putative.	0.981
AFUA_1G02430	AFUA_6G04670	Q4WKH7	Q4WDG5	Ubiquitin fusion degradation protein Ufd1, putative.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.977
AFUA_1G02430	AFUA_7G04320	Q4WKH7	Q4WGA2	Ubiquitin fusion degradation protein Ufd1, putative.	UBX domain protein (Ubx5), putative.	0.985
AFUA_1G02430	AFUA_7G05752	Q4WKH7	A4D9X0	Ubiquitin fusion degradation protein Ufd1, putative.	AAA family ATPase, putative.	0.637
AFUA_1G02430	AFUA_7G06680	Q4WKH7	Q4WGY6	Ubiquitin fusion degradation protein Ufd1, putative.	AAA family ATPase, putative.	0.637
AFUA_1G02430	AFUA_8G00780	Q4WKH7	Q4WB23	Ubiquitin fusion degradation protein Ufd1, putative.	Uncharacterized protein.	0.637
AFUA_1G02430	AFUA_8G04840	Q4WKH7	Q4WCD2	Ubiquitin fusion degradation protein Ufd1, putative.	RING finger protein.	0.727
AFUA_1G02430	npl4	Q4WKH7	Q4WKD7	Ubiquitin fusion degradation protein Ufd1, putative.	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	0.999
AFUA_1G02430	yos9	Q4WKH7	Q4WCG2	Ubiquitin fusion degradation protein Ufd1, putative.	Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).	0.580
AFUA_1G14690	AFUA_1G02430	A4D9K5	Q4WKH7	Ubiquitin-protein ligase Sel1/Ubx2, putative.	Ubiquitin fusion degradation protein Ufd1, putative.	0.592